Mitochondrial Function, Part B,457, Allison, William S.
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Автор: Allison, William S. Название: Mitochondrial Function, Part A,456 ISBN: 0080877761 ISBN-13(EAN): 9780080877761 Издательство: Elsevier Science Рейтинг: Цена: 26275.00 р. Наличие на складе: Поставка под заказ.
Описание: Presents modern methods that have been developed to examine mitochondrial electron transport chain complexes, iron-sulfur proteins and reactive oxygen species. This title is suitable for researchers in all fields of life sciences.
Автор: J.J. Lemasters; C.R. Hackenbrock; R.G. Thurman; H. Название: Integration of Mitochondrial Function ISBN: 1489925538 ISBN-13(EAN): 9781489925534 Издательство: Springer Рейтинг: Цена: 30039.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Volkmar Weissig; Marvin Edeas Название: Mitochondrial Medicine ISBN: 1493922874 ISBN-13(EAN): 9781493922871 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This expert volume covers an interdisciplinary and rapidly growing area of biomedical research comprising genetic, biochemical, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction.
Автор: Justin C. St. John Название: Mitochondrial DNA, Mitochondria, Disease and Stem Cells ISBN: 1627038671 ISBN-13(EAN): 9781627038676 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The reader is then introduced to how mtDNA is transmitted through the oocyte and how stem cells can be used to study mitochondrial biogenesis and mtDNA replication and transcription in undifferentiated pluripotent and differentiating cells and how mitochondria adapt during this process.
Автор: J.J. Lemasters; C.R. Hackenbrock; R.G. Thurman; H. Название: Integration of Mitochondrial Function ISBN: 0306429993 ISBN-13(EAN): 9780306429996 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In aerobic tissues such as heart, brain, kidney, liver and brown fat, mitochon- dria account for more than 20% of cell protein and play an essential role in res- piration, ATP formation, ketogenesis, gluconeogenesis, amino acid metabolism, ureagenesis, thermogenesis and a variety of other metabolic activities. The mecha- nisms by which these activities are integrated and regulated within the overall context of cellular physiology is of much current research interest. In order to bring together scientists examining the various diverse aspects of this overall pro- blem, an International Conference on INTEGRATION OF MITOCHONDRIAL FUNC- TION was held June 4-7, 1987 at the Hanes Art Center on the campus of the Uni- versity of North Carolina at Chapel Hill. The chapters of this volume derive from presentations made at this conference. The focus of INTEGRATION OF MITOCHONDRIAL FUNCTION is on signifi- cant new experimental and theoretical advances concerning integration of mito- chondrial function at the organelle, cell, tissue and whole organism levels of organization.
Автор: Angelo Azzi; Katarzyna A. Nalecz; Maciej J. Nalecz Название: Anion Carriers of Mitochondrial Membranes ISBN: 3642745415 ISBN-13(EAN): 9783642745416 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: All relevant structural and functional aspects of the Anion Carriers of Mitochondrial Membranes as well as isolation procedures, reconstitution experiments and biogenesis of the carriers, kinetics of transport as well as the metabolic regulation mechanisms are treated in this volume.
Автор: Hong Kyu Lee; Salvatore DiMauro; Masashi Tanaka; Y Название: Mitochondrial Pathogenesis ISBN: 1573314919 ISBN-13(EAN): 9781573314916 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Lee-Jun C. Wong Название: Mitochondrial Disorders ISBN: 1493959506 ISBN-13(EAN): 9781493959501 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The variability of clinical symptoms in mitochondrial diseases calls for a systematic presentation of the full range of protocols used in their assessment. This volume provides cutting-edge methods of analysis as well as expert guidance on how to apply them.
Автор: Carlos M. Palmeira; Anabela P. Rolo Название: Mitochondrial Regulation ISBN: 1493946129 ISBN-13(EAN): 9781493946129 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. Isolation of Crud Mitochondrial Fraction from Cells
Mariusz R. Wieckowski and Lech Wojtczak
2. Isolation of Mitochondria from Liver and Extraction of Total RNA and Protein - Analyses of MicroRNA and Protein Expressions
Pedro M. Borralho, Clifford J. Steer, and Cecнlia M. P. Rodrigues
3. PCR Based Determination of Mitochondrial DNA Copy Number in Multiple Species
5. Measuring PGC-1α and its Acetylation Status in Mouse Primary Myotubes
Ana P. Gomes and David A. Sinclair
6. Measurement of Mitochondrial Oxygen Consumption Rates in Mouse Primary Neurons and Astrocytes
Sofia M. Ribeiro, Alfredo Gimйnez-Cassina, and Nika N. Danial
7. Determination Of Oxidative Phosphorylation Complexes Activities
Joгo S. Teodoro, Carlos M. Palmeira, and Anabela P. Rolo
8. Histoenzymatic Methods for Visualization of the Activity of Individual Mitochondrial Respiratory Chain Complexes in the Muscle Biopsies from Patients with Mitochondrial Defects
Agnieszka Karkucinska-Wieckowska, Maciej Pronicki, and Mariusz R. Wieckowski
9. A Method Aimed at Assessing the Functional Consequences of the Supramolecular Organization of the Respiratory Electron Transfer Chain by Time-resolved Studies
Fabrice Rappaport
10. BN-PAGE-based Approach to Study Thyroid Hormones and Mitochondrial Function
Elena Silvestri, Assunta Lombardi, Federica Cioffi, and Fernando Goglia
11. Detection of UCP1 Protein and Measurements of Dependent GDP-Sensitive Proton Leak in Non-Phosphorylating Thymus Mitochondria
Kieran J. Clarke, Audrey M. Carroll, Gemma O'Brien & Richard K. Porter
12. Exploring Liver Mitochondrial Function By 13c-Stable Isotope Breath Tests. Implications In Clinical Biochemistry
Ignazio Grattagliano, Leonilde Bonfrate, Michele Lorusso, Luigi Castorani, Ornella de Bari, and Piero Portincasa
13. Following Mitochondria Dynamism: Confocal Analysis of The Organelle Morphology
F. R. Mariotti, M. Corrado, and S. Campello
14. Analysis of Pro-apoptotic Protein Trafficking to and From Mitochondria
Ignacio Vega-Naredo, Teresa Cunha-Oliveira, Teresa Serafim, Vilma Sardao, and Paulo J. Oliveira
15. Mitophagy and Mitochondrial Balance
Simone Patergnani and Paolo Pinton
Автор: Tatiana K. Rostovtseva Название: Molecular Basis for Mitochondrial Signaling ISBN: 3319555375 ISBN-13(EAN): 9783319555379 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: At last, the molecular identity of two important channels in the mitochondrial inner membrane, the mitochondrial calcium uniporter and the mitochondrial permeability transition pore have been established.
Автор: Palmeira Название: Mitochondrial Bioenergetics ISBN: 1493978306 ISBN-13(EAN): 9781493978304 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Preface...Table of Contents...Contributing Authors... 1. Overview of Mitochondrial BioenergeticsVitor M.C. Madeira 2. Evaluation of Respiration with Clark Type Electrode in Isolated Mitochondria and Permeabilized Animal CellsAna M. Silva and Paulo J. Oliveira 3. High-Resolution FluoRespirometry and OXPHOS Protocols for Human Cells, Permeabilized Fibres from Small Biopsies of Muscle and Isolated MitochondriaCarolina Doerrier, Luiz F. Garcia-Souza, Gerhard Krumschnabel, Yvonne Wohlfarter, Andrбs T. Mйszбros, and Erich Gnaiger 4. High-Throughput Analysis of Mitochondrial Oxygen ConsumptionJames Hynes, Rachel L. Swiss, and Yvonne Will 5. Modulation of Cellular Respiration by Endogenously Produced Nitric Oxide in Rat Hippocampal SlicesAna Ledo, Rui M. Barbosa, and Joгo Laranjinha 6. Mitochondrial Membrane Potential (ΔΨ) Fluctuations Associated with the Metabolic States of MitochondriaJoгo S. Teodoro, Anabela P. Rolo, and Carlos M. Palmeira 7. Fluorescence Measurement of Mitochondrial Membrane Potential Changes in Cultured CellsDavid G. Nicholls 8. Comparison of Mitochondrial Incubation Media for Measurement of Respiration and Hydrogen Peroxide ProductionTimea Komlуdi, Ondrej Sobotka, Gerhard Krumschnabel, Nicole Bezuidenhout, Elisabeth Hiller, Carolina Doerrier, and Erich Gnaiger 9. Measurement of Proton Leak in Isolated MitochondriaCharles Affourtit, Hoi-Shan Wong, and Martin D. Brand 10. Imaging Mitochondrial Calcium Fluxes with Fluorescent Probes and Single or Two Photon Confocal MicroscopySean M. Davidson and Michael R. Duchen 11. Mitochondrial Permeability Transition Pore and Calcium HandlingRandi J. Parks, Elizabeth Murphy, and Julia C. Liu 12. Redox Equivalents and Mitochondrial BioenergeticsJames R. Roede, Young-Mi Go, and Dean P. Jones 13. Mitochondrial Bioenergetics by 13 C-NMR Isotopomer AnalysisRui A. Carvalho 14. Computational Modeling of Mitochondrial Function from a Systems Biology PerspectiveSonia Cortassa, Steven J. Sollott, and Miguel A. Aon 15. Monitoring the Mitochondrial Dynamics in Mammalian CellsLuca Simula and Silvia Campello 16. Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated MitochondriaHoi-Shan Wong, Pierre-Axel Monternier, Adam L. Orr, and Martin D. Brand 17. Plate-Based Measurement of Respiration by Isolated MitochondriaShona A. Mookerjee, Casey L. Quinlan, Helen Wong, Pratiksha Dighe, and Martin D. Brand 18. Detection of Iron Depletion- and Hypoxia-Induced Mitophagy in Mammalian CellsShun-ichi Yamashita and Tomotake Kanki 19. The Importance of Calcium Ions for Determining Mitochondrial Glycerol-3-Phosphate Dehydrogenase Activity When Measuring Uncoupling Protein 1 (UCP1) Function in Mitochondria Isolated from Brown Adipose TissueKieran J. Clarke and Richard K. Porter 20. Isolation and Analysis of Mitochondrial Small RNAs from Rat Liver Tissue and HepG2 CellsJulian Geiger and Louise T. Dalgaard 21. Imaging of Mitochondrial pH Using SNARF-1Venkat K. Ramshesh and John J. Lemasters 22. Relation between Mitochondrial Membrane Potential and ROS FormationJan Suski, Magdalena Lebiedzinska, Massimo Bonora, Paolo Pinton, Jerzy Duszynski, and Mariusz R. Wieckowski
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