Epigenetic Processes and Evolution of Life, Markos, Anton (Charles University, Faculty of Science, Praha, Czech Republis) Svorcova, Jana
Автор: Johannes Backs, Timothy McKinsey Название: Epigenetics in Cardiac Disease ISBN: 3319414550 ISBN-13(EAN): 9783319414553 Издательство: Springer Рейтинг: Цена: 14673.00 р. 20962.00-30% Наличие на складе: Есть (1 шт.) Описание: This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.
Автор: Vorcova Название: Epigenetic Processes and Evolution of Life ISBN: 1138541923 ISBN-13(EAN): 9781138541924 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers the possible story of emergence of life and its subsequent evolution, emphasizing the necessary evolutionary step - negotiation of a common "language set" which kept all inhabitants in biosphere together, ensuring a basic level of understanding among them.
Автор: Cabej, Nelson R. (department Of Biology, Universit Название: Epigenetic mechanisms of the cambrian explosion ISBN: 0128143118 ISBN-13(EAN): 9780128143117 Издательство: Elsevier Science Рейтинг: Цена: 11957.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Epigenetic Mechanisms of the Cambrian Explosion provides readers with a basic biological knowledge and epigenetic explanation of the biological puzzle of the Cambrian explosion, the unprecedented rapid diversification of animals that began 542 million years ago. During an evolutionarily instant of 10 million years, which represents only 0.3% of the time of existence of life on Earth, or less than 2% of the time of existence of metazoans, all of the 30 extant body plans, major animal groups (phyla) and several extinct groups appeared. The work helps address this phenomena and tries to answer remaining questions for evolutionary biology, epigenetics, and scientific researchers.
The book recognizes and presents objective representations of alternative theories for epigenetic evolution in this period, with the author drawing on his epigenetic theory of evolution to explain the causal basis of the Cambrian explosion. Both empirical evidence and theoretical arguments are presented in support of this thought-provoking epigenetic theory.
Explains the Cambrian explosion from an entirely epigenetic view
Takes a causal rather than descriptive approach to the phenomenon
Allows for a broad readership, including those with only a basic biological knowledge, while maintaining scientific rigor
Автор: Vladimir A. Botchkarev; Sarah E. Millar Название: Epigenetic Regulation of Skin Development and Regeneration ISBN: 3030132374 ISBN-13(EAN): 9783030132378 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Поставка под заказ.
Описание: This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development and Regeneration uncovers the fundamental significance of epigenetic mechanisms in skin development and regeneration, and emphasizes the development of new therapies for a number of skin disorders, such as pathological conditions of epidermal differentiation, pigmentation and carcinogenesis. At least six categories of researchers will find this book essential, including stem cell, developmental, hair follicle or molecular biologists, and gerontologists or clinical dermatologists.
Автор: Vladimir Botchkarev; Sarah Millar Название: Epigenetic Regulation of Skin Development and Regeneration ISBN: 3319167685 ISBN-13(EAN): 9783319167688 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development and Regeneration uncovers the fundamental significance of epigenetic mechanisms in skin development and regeneration, and emphasizes the development of new therapies for a number of skin disorders, such as pathological conditions of epidermal differentiation, pigmentation and carcinogenesis. At least six categories of researchers will find this book essential, including stem cell, developmental, hair follicle or molecular biologists, and gerontologists or clinical dermatologists.
Описание: This book presents a major research program on epigenetic mechanisms of cell programming and reprogramming. The program was launched by the National Natural Science Foundation of China during the 11th Five-Year Plan period, which was started in October 2008 and concluded at the end of 2016. It first summarizes the epigenetic research plans and the current situation of epigenetic research in China and the international frontier. With the application of interdisciplinary research methods, the book discusses the development trends of epigenetic research, such as mechanisms of establishment and maintenance of epigenetic information and epigenetic regulation on reproduction and development. It also presents a variety of research achievements. For example, the discovery of new epigenetic regulators and chromatin remodulaters and their biological functions and mechanisms are highlighted. Several regulation mechanisms of cell differentiation and trans-differentiation are discussed, especially the discovery of the key factors to promote the trans-differentiation of somatic cells to hepatocytes. In addition, this book puts forward some key academic fields with increasing importance, such as biochemistry, cell biology, and clinical medicine. Given its scope, the book is of interest to researchers who work in cell biology, biochemistry, structural biology, bioinformatics, clinical medicine, and other related fields.
Автор: C.D. Rollo Название: Phenotypes ISBN: 0412410303 ISBN-13(EAN): 9780412410307 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Incorporates modern molecular knowledge of genes into an evolutionary framework, stressing the importance of genomic integration in the evolution of multicellular phenotypes. This text reinterprets epigenetics, the evolution of sex and the evolution of longevity assurance systems.
Автор: Moskalev, Alexey Название: Epigenetics of Aging and Longevity ISBN: 0128110600 ISBN-13(EAN): 9780128110607 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Поставка под заказ.
Описание:
Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses--including cancer and cardiovascular, metabolic, and neurodegenerative diseases--are explored in detail.
This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease.
Автор: Ayyanathan, Kasirajan Название: Epigenetics and Pathology ISBN: 1774633051 ISBN-13(EAN): 9781774633052 Издательство: Taylor&Francis Рейтинг: Цена: 12707.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Paro Renato, Grossniklaus Ueli, Santoro Raffaella Название: Introduction to Epigenetics ISBN: 3030686698 ISBN-13(EAN): 9783030686697 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Murder seems to follow young Tommy McBride everywhere. Only five years after the death of his family, a freak accident on a sheep station sends him fleeing into the wilderness of the Australian outback, the station overseer lying dead behind him with his head smashed on a rock. But Tommy is haunted by more than the death of his family - both he and his brother Billy witnessed a vicious state-sanctioned massacre of the Kurrong people, and they havent seen each other since.When an official inquiry is launched into the slaughter, the successful life that Billy has built for himself is under threat. He desperately needs to find his brother, long
Автор: Manel Esteller Название: DNA Methylation, Epigenetics and Metastasis ISBN: 9048169178 ISBN-13(EAN): 9789048169177 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Philippe Jeanteur Название: Epigenetics and Chromatin ISBN: 3540852360 ISBN-13(EAN): 9783540852360 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Emphasizes on the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility. This work deals with parental genomic imprinting, a process which allows to express a few selected genes from only one of the parental allele while extinguishing the other.
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