This book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the area advancing rapidly. It is now possible to prepare extremely complex systems using multi-fluid processes, and to increase production rates to an industrial scale. Electrospun formulations can be produced under GMP conditions and are in clinical trials.
In this volume, we explore a range of topics around electrospinning and electrospraying in controlled drug delivery. Four reviews cover the exciting potential of cyclodextrin-containing fibers and the many potential biomedical applications of electrospun fibers. The use of electrospinning to prepare amorphous systems and improve the dissolution rate and solubility of poorly soluble active ingredients is addressed, and the possibilities of such materials in tissue engineering are comprehensively covered.
The six original research papers cover the effect of molecular properties on API release from Eudragit-based electrospun fibers; ferulic acid solid dispersions; electrospun medicines to treat psoriasis; scale up of electrospinning and its use to produce low-dose tablets; transepithelial permeation of drugs released from electrospun fibers, and the possibilities for the synergistic chemophotothermal treatment of cancer.
Автор: Gad, Shayne C. Название: Nonclinical Drug Administration ISBN: 1466502533 ISBN-13(EAN): 9781466502536 Издательство: Taylor&Francis Рейтинг: Цена: 27562.00 р. Наличие на складе: Поставка под заказ.
Название: Photostability of Drugs and Drug Formulations ISBN: 0367394103 ISBN-13(EAN): 9780367394103 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Providing the guidance needed for formulation, handling, and quality control of photolabile drugs, Photostability of Drugs and Drug Formulations, Second Edition explores the significance of new information on drug photoreactivity in a pharmaceutical context. Completely revised and updated, with chapter authors drawn from an international panel of experts, the book supplies the background necessary for planning standardized photochemical stability studies as a part of drug development and formulation work. It contains comprehensive coverage of the physical and chemical aspects of drug photoreactivity, formulation, stability testing, and drug design/discovery in one resource.
The contents have been reorganized to focus on the standardization of photostability testing of drug substances and products, in vitro photoreactivity screening of drugs, and various aspects of the formulation of photoreactive substances. The information on in vitro screening of drug photoreactivity is of great relevance for scientists who are developing and validating a set of testing protocols to address photosafety. Discussing kinetic and chemical aspects of drug photodecomposition as well as the practical problems frequently encountered in photochemical stability testing, this book helps you design a test protocol and interpret the results. Features
Assists non-experts in this field design a test protocol and interpret the results
Covers in vitro and in vivo aspects of interactions between drugs and light
Explores the kinetic and chemical aspects of drug photodecomposition
Discusses the problems frequently encountered in photochemical stability testing
Provides guidance on how to address photosafety assessments and labeling requirements of potentially photoreactive drugs
Highlights the practical implications of drug photodecomposition from a pharmaceutical viewpoint
Offers specific guidance in photos
Автор: T?nnesen, Hanne Название: Photostability of Drugs and Drug Formulations ISBN: 0415303230 ISBN-13(EAN): 9780415303231 Издательство: Taylor&Francis Рейтинг: Цена: 53592.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume One, Compressed Solid Products is an authoritative and practical guide to the art and science of formulating drugs for commercial manufacturing. With thoroughly revised and expanded content, this first volume of a six-volume set, compiles data from FDA new drug applications, patent applications, and other sources of generic and proprietary formulations to cover the broad spectrum of GMP formulations and issues in using these formulations in a commercial setting. A must-have collection for pharmaceutical manufacturers, educational institutions, and regulatory authorities, this is an excellent platform for drug companies to benchmark their products and for generic companies to formulate drugs coming off patent.
Автор: Aruqaj, Bujar (Freie Universitat Berlin, Germany) Название: Natural Products and Nano-Formulations in Cancer Chemoprevention ISBN: 103231303X ISBN-13(EAN): 9781032313030 Издательство: Taylor&Francis Рейтинг: Цена: 24499.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers various aspects of cancer chemoprevention including overview of chemoprevention in the process of tumorigenesis, and role of various phytochemicals, functional foods, and dietary interventions in disease prevention, and techniques such as cancer stem cell targeting, nano-formulations, and so forth.
Автор: Singh, Amritpal Название: Regulatory and Pharmacological Basis of Ayurvedic Formulations ISBN: 0367782928 ISBN-13(EAN): 9780367782924 Издательство: Taylor&Francis Рейтинг: Цена: 7348.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Regulatory affairs and pharmacological drug safety issues of Ayurvedic medicine has been overlooked by practitioners for many years. Research in Ayurveda is now a world-wide phenomenon, and several large pharmaceutical corporations are investing money for novel drug discovery from Ayurvedic sources. This book examines the regulatory and pharmaco
Автор: Walters, Kenneth A. Название: Dermatological and Transdermal Formulations ISBN: 0824798899 ISBN-13(EAN): 9780824798895 Издательство: Taylor&Francis Рейтинг: Цена: 31390.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Hauss, David J. Название: Oral Lipid-Based Formulations ISBN: 0824729455 ISBN-13(EAN): 9780824729455 Издательство: Taylor&Francis Рейтинг: Цена: 27562.00 р. Наличие на складе: Поставка под заказ.
Описание: The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume Two, Uncompressed Solid Products is an authoritative and practical guide to the art and science of formulating drugs for commercial manufacturing.
Автор: Daniel Bar-Shalom; Klaus Rose Название: Pediatric Formulations ISBN: 1493945211 ISBN-13(EAN): 9781493945214 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed.
Автор: John F. Carpenter; Mark C. Manning Название: Rational Design of Stable Protein Formulations ISBN: 1461351316 ISBN-13(EAN): 9781461351313 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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