RNA-Seq in Drug Discovery and Development, Cheng, Feng

Автор: Wood Clive R
Название: Antibody Drug Discovery
ISBN: 1848166281 ISBN-13(EAN): 9781848166288
Издательство: World Scientific Publishing
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Цена: 24552.00 р.
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Описание: Antibody-based therapeutics are a central driver of the success of biopharmaceuticals. The discovery technology of this field is isolated to a limited number of centers of excellence in industry and academia. This title offers guidance to those evaluating and preparing to enter particular areas within the field.

Автор: Li
Название: The Drug Discovery Experience: Practices, Processes, and Perspectives
ISBN: 0470942355 ISBN-13(EAN): 9780470942352
Издательство: Wiley
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Цена: 12302.00 р. 17574.00 -30%
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Описание: Edited by two distinguished chemists from academia and industry, this book presents an up-to-date overview of major aspects of drug discovery. It covers all ends of the discovery process from target selection to major therapeutic areas.

Автор: Caffrey
Название: Parasitic Helminths: Targets, Screens, Drugs and Vaccines
ISBN: 3527330593 ISBN-13(EAN): 9783527330591
Издательство: Wiley
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Цена: 12856.00 р. 18366.00 -30%
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Описание: The first title dealing with drug discovery against parasitic worms (Helminths) which include many of the major human and animal parasites. The book focusses on the development of novel drugs and vaccination strategies making it attractive for academia and industry alike.

Автор: Nicola J. Curtin; Ricky A. Sharma
Название: PARP Inhibitors for Cancer Therapy
ISBN: 3319141503 ISBN-13(EAN): 9783319141503
Издательство: Springer
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Цена: 23757.00 р.
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Описание: PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. PARP plays a pivotal role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer.

Автор: Alcazar Jesus, de la Hoz Antonio, Dнaz-Ortiz Angel
Название: Flow Chemistry in Drug Discovery
ISBN: 3030855910 ISBN-13(EAN): 9783030855918
Издательство: Springer
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Цена: 41925.00 р.
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Описание: Flow Chemistry in Drug Discovery: Challenges and Opportunities.- Green aspects of Flow Chemistry for Drug Discovery.- New process windows for synthesis of bioactive compounds.- Asymmetric catalysis in flow for Drug Discovery.- Organocatalysis in flow for Drug Discovery.- Biocatalysis in flow for Drug Discovery.- Photochemistry in flow for Drug Discovery.- Electrochemistry in flow for Drug Discovery.- Drug Discovery automation and library synthesis in flow.- Improved synthesis of bioactive molecules through Flow Chemistry.- Flash Chemistry in microsystems for Drug Discovery.- New biomass reagents for synthesis of bioactive compounds.- Flow Chemistry supporting access to Drug Discovery in Development countries.

Автор: Curtin Nicola J., Sharma Ricky A.
Название: Parp Inhibitors for Cancer Therapy
ISBN: 3319344897 ISBN-13(EAN): 9783319344898
Издательство: Springer
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Цена: 20962.00 р.
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Описание: PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. The volume covers the history of the discovery of PARP (poly ADP ribose polymerase) and its role in DNA repair. In addition, a description of discovery of the PARP family, and other DNA maintenance-associated PARPs will also be discussed. The volume also features a section on accessible chemistry behind the development of inhibitors. PARP inhibitors are a group of pharmacological inhibitors that are a particularly good target for cancer therapy. PARP plays a pivotal role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer. Researchers have learned a tremendous amount about the biology of PARP and how tumour-specific defects in DNA repair can be exploited by PARPi. The “synthetic lethality” of PARPi is an exciting concept for cancer therapy and has led to a heightened activity in this area.

Автор: Gad
Название: Drug Discovery HB.2005
ISBN: 0471213845 ISBN-13(EAN): 9780471213840
Издательство: Wiley
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Цена: 30888.00 р.
Наличие на складе: Поставка под заказ.

Описание: The Drug Discovery Handbook gives the professional a comprehensive, practical guide for professionals the latest techniques and methods in drug discovery, including genomics, involved in drug discovery. This practical guide will present an explanation of proteomics, high throughput screening, and systems biology. This resource summarizes how these techniques and methods are used to discover new central nervous system agents, antiviral agents, respiratory drugs, oncology drugs, etc. Individual chapters detail specific approaches to drug discovery, including problems that are encountered, solutions to these problems, and limitations of various methods and techniques.

Автор: Li, Jie Jack (revolution Medicines, California, Usa) Yang, Minmin
Название: Drug discovery with privileged building blocks
ISBN: 1032041684 ISBN-13(EAN): 9781032041681
Издательство: Taylor&Francis
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Цена: 11482.00 р.
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Описание: Drug Discovery with Privileged Building Blocks traces back PharmaBlock`s founding philosophy of designing privileged building blocks. Each chapter may be read and studied without learning the previous chapters. This book will be a good starting point for novice medicinal chemists and veteran medicinal chemists find it useful as well.

Автор: Alexander Heifetz
Название: Quantum Mechanics in Drug Discovery
ISBN: 1071602810 ISBN-13(EAN): 9781071602812
Издательство: Springer
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Цена: 18167.00 р.
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Автор: Kesharwani, Prashant
Название: Drug Discovery Targeting Drug-Resistant Bacteria
ISBN: 0128184809 ISBN-13(EAN): 9780128184806
Издательство: Elsevier Science
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Цена: 26444.00 р.
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Описание:

Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included.

Название: Protein Structure
ISBN: 0367395347 ISBN-13(EAN): 9780367395346
Издательство: Taylor&Francis
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Цена: 9798.00 р.
Наличие на складе: Нет в наличии.

Описание: This text offers in-depth perspectives on every aspect of protein structure identification, assessment, characterization, and utilization, providing a clear understanding of the diversity of protein shapes, variations in protein function, and structure-based drug design. The authors cover numerous high-throughput technologies as well as computational methods to study protein structures and residues. The book reflects current trends in the effort to solve new structures arising from genome initiatives, details methods to detect and identify errors in the prediction of protein structural models, and outlines challenges in the conversion of routine processes into high-throughput platforms.

Автор: Gabriele Proetzel; Michael V. Wiles
Название: Mouse Models for Drug Discovery
ISBN: 149393659X ISBN-13(EAN): 9781493936595
Издательство: Springer
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Цена: 20962.00 р.
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Описание: Herein, these models are appliedto a wide field of disease areas, including diabetes, cardiovascular disease,skin disorders, cancer, neurodegenerative and neuromuscular diseases, retinaldisorders, as well as various behavioral models.