This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Mishra Название: Nanomedicine for Drug Delivery and Therapeutics ISBN: 1118414098 ISBN-13(EAN): 9781118414095 Издательство: Wiley Рейтинг: Цена: 20507.00 р. 29296.00-30% Наличие на складе: Есть (1 шт.) Описание: This book describes a broad area of nanomedicine which involves mainly applications, diseases, and diagnostics. The comprehensive coverage provides researchers, academics, and health specialists with a great tool, that includes techniques applicable to various uses.
Автор: Kumar, Arun Название: Nanomedicine in Drug Delivery ISBN: 1466506164 ISBN-13(EAN): 9781466506169 Издательство: Taylor&Francis Рейтинг: Цена: 31390.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Das, Undurti N. Название: Nanomedicines for Brain Drug Delivery ISBN: 1071608401 ISBN-13(EAN): 9781071608401 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Authoritative and cutting-edge, Mitochondrial Gene Expression: Methods and Protocols aims to provide complementary approaches and practical guidelines. Chapter 7 is available Open Access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Автор: Basha, Mahin Название: Supramolecules in Drug Discovery and Drug Delivery ISBN: 107160922X ISBN-13(EAN): 9781071609224 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed book aims to provide readers with critical information to accomplish the synthesis of nanosystems for the purpose of supramolecular entities complexing with drugs, targeted drug delivery system characterization, as well as the study of the physical-chemical interactions that govern the stability and properties of these systems.
Автор: Nayak, Amit Kumar Название: Tailor-Made Polysaccharides In Drug Delivery ISBN: 0128212861 ISBN-13(EAN): 9780128212868 Издательство: Elsevier Science Рейтинг: Цена: 26444.00 р. Наличие на складе: Поставка под заказ.
Описание: Gathers a prominent group of global researchers who share expert knowledge and views on diabetes. Readers will gain insights into groundbreaking therapies and approaches to preventing and managing diabetes complications. The book, a result of the 3rd Cambridge-Oxford-Sunway Biomedical Symposium, further shares the most recent advances in diabetes research from a Malaysian perspective.
Автор: P Vyas, Suresh Название: Smart Polymeric Nano-Constructs In Drug Delivery ISBN: 0323912486 ISBN-13(EAN): 9780323912488 Издательство: Elsevier Science Рейтинг: Цена: 26107.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Any student of the New Testament must be conscious of the competing expectations in ancient Jewish thought of what and who the Messiah would be. In King and Messiah, Aage Bentzen offers a fascinating glimpse into this topic, which preoccupied the most eminent Scandinavian biblical scholars of the mid-twentieth century.Beginning with the Messiah described in many of the Psalms, representing a demythologised form of the Oriental concept of kingship, Bentzen proceeds to the eschatological Messiah of Isaiah and Micah. He next discusses the later, prophetic-Messianic Moses Redivivus of Deutero-Isaiah, reaching the final
Автор: Rathbone, Michael J. Название: Modified-Release Drug Delivery Technology ISBN: 1420053558 ISBN-13(EAN): 9781420053555 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Поставка под заказ.
Oral health is general health. If the oral cavity is kept healthy, the whole body is always healthy. Bacteria in the oral cavity do not stay in the oral cavity, but rather they travel throughout the body and can induce various diseases. Periodontal pathogens are involved in tooth loss. The number of remaining teeth decreases with age. People with more residual teeth can bite food well and live longer with lower incidence of dementia. There are many viruses in the oral cavity that also cause various diseases. Bacteria and viruses induce and aggravate inflammation, and therefore should be removed from the oral cavity. In the natural world, there are are many as yet undiscovered antiviral, antibacterial and anti-inflammatory substances. These natural substances, as well as chemically modified derivatives, help our oral health and lead us to more fulfilling, high quality lives. This Special Issue, entitled "Biological Efficacy of Natural and Chemically Modified Products against Oral Inflammatory Lesions", was written by specialists from a diverse variety of fields. It serves to provide readers with up-to-date information on incidence rates in each age group, etiology and treatment of stomatitis, and to investigate the application of such treatments as oral care and cosmetic materials.
Автор: Juergen Siepmann; Ronald A. Siegel; Michael J. Rat Название: Fundamentals and Applications of Controlled Release Drug Delivery ISBN: 1489986464 ISBN-13(EAN): 9781489986467 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms.
Автор: Anya M Hillery Название: Drug Delivery Fundamentals and Applications, Second Edition ISBN: 1482217716 ISBN-13(EAN): 9781482217711 Издательство: Taylor&Francis Рейтинг: Цена: 18374.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book provides a comprehensive introduction to advanced drug delivery and targeting, covering their principles, current applications, and potential future developments. This edition has been updated to reflect significant trends and cutting-edge advances that have occurred since the first edition was published. All the original chapters have been retained, but the material therein has been updated. Eight new chapters have been added that deal with entirely new technologies and approaches.
Features:
Offers a comprehensive introduction to the fundamental concepts and underlying scientific principles of drug delivery and targeting
Presents an in-depth analysis of the opportunities and obstacles afforded by the application of nanotechnologies for drug delivery and targeting
Includes a revised and expanded section on the major epithelial routes of drug delivery currently under investigation
Describes the most recent, emerging, and innovative technologies of drug delivery
Provides real-life examples of the clinical translation of drug delivery technologies through the use of case studies
Discusses the pertinent regulatory hurdles and safety issues of drug delivery and targeting systems--crucial considerations in order to achieve licensing approval for these new technologies
Описание: This book highlights the advances in drug discovery and delivery and the need for emerging technologies. The text describes new micro and nanofabrication techniques, including methods like electrohydrodynamic processes, additive manufacturing, and microfluidics, which have potential to produce drug delivery systems that were not possible before.
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