Описание: Despite many encouraging developments in the field of animal-free technologies, well-defined animal models are still needed to study fundamental properties of human diseases and to develop new prophylactic and therapeutic treatments against human diseases. Non-human primates (NHP) make up only a small, but important, part of the total number of animals used in biomedical and preclinical research. Due to their close phylogenetic relationship and the shared susceptibility to many human diseases, NHP can provide important research models to study these diseases and, as such, play a critical role in the advancement of various areas in the medical field. Studies in NHP have contributed to our understanding of various diseases and fundamental biological phenomena and they continue to be important in the development of new therapies, treatments, drugs and vaccines. Moreover, NHP models also contribute to our general knowledge of the processes that underlie non-disease and disease conditions. Important areas where NHP can provide important information include (emerging) infectious diseases, organ transplantation, neurological and aging-related disorders. Although not covered in this book due to time constraints, the need for, and benefits of, NHP models has been demonstrated most recently in the SARS-CoV-2 pandemic. The present book is the second of two volumes and covers important disease areas where NHP are used as model species. This volume includes different chapters on NHP models in infectious diseases, aging, neurodegenerative disorders, organ transplantation and cancer.
Автор: Sapp, Jan Название: Microbial Phylogeny and Evolution ISBN: 0195168771 ISBN-13(EAN): 9780195168778 Издательство: Oxford Academ Рейтинг: Цена: 10454.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The extent of lateral gene transfer among diverse microbes has effectively broken down our concept of species when we seek to apply it to the microbial world. The explosive growth of whole genome sequences for a great number of microbes give us an unprecedented perspective on the entire process of cellular evolution known. The field is rife with controversies, which have been waged fiercely over the past 20 years and which now are all coming to a point of resolution. Sapp has brought together the best workers in this field to assess what we now know, and to try to reach an accommodation and consensus on the broad outline of how cellular life has evolved.
Автор: Taylor Adrian Название: Evolutionary Biomechanics ISBN: 0198566387 ISBN-13(EAN): 9780198566380 Издательство: Oxford Academ Рейтинг: Цена: 6651.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent research in biomechanics is increasingly revealing a set of special cases where universal physical laws constrain the trajectories and, more controversially, even the endpoints of the evolutionary process. For the first time this book brings together a broad range of examples from the latest research in evolutionary biomechanics to examine this phenomenon.
Автор: Cox Название: Evolution of the Rodents ISBN: 1107044332 ISBN-13(EAN): 9781107044333 Издательство: Cambridge Academ Рейтинг: Цена: 16474.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book brings together the latest research on rodents to better understand the evolution of both living and extinct members of this fascinating group. Highlighting interdisciplinary links across palaeontology, developmental biology, functional morphology, phylogenetics and biomechanics, it is a valuable resource for evolutionary biologists in all fields.
Автор: Timothy D. Smith, Valerie B. DeLeon, Christopher J. Vinyard, Jesse W. Young Название: Skeletal Anatomy of the Newborn Primate ISBN: 1107152690 ISBN-13(EAN): 9781107152694 Издательство: Cambridge Academ Рейтинг: Цена: 15523.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The first book to provide a broad comparison of skeletal and dental anatomy in subadult primates. With hundreds of anatomical illustrations and detailed descriptions, it is a valuable resource for students and researchers in the fields of biological anthropology, anatomy, primatology, growth and development, dental biology, and veterinary medicine.
Автор: Behie Alison Название: Primate Research and Conservation in the Anthropocene ISBN: 1316610217 ISBN-13(EAN): 9781316610213 Издательство: Cambridge Academ Рейтинг: Цена: 6811.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is a holistic treatment of primate conservation research. Featuring a range of personal narratives, researchers reveal their motivations and strategies for confronting the threats pushing primates towards extinction. It will appeal to anyone interested in wildlife conservation who wants to learn about research methods and motivations.
Автор: Manoranjan Prasad Sinha Название: Primate Biogeography ISBN: 1774076101 ISBN-13(EAN): 9781774076101 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 22730.00 р. Наличие на складе: Нет в наличии.
Описание: Explores various aspects related to the lives of the primates, including their habitats, their growth characteristics, their distribution across the globe, their development stages, and the various forms in which they are found.
Описание: Due to the phylogenetic relationship and close genetic and biological similarities with humans, non-human primates (NHP) are regularly used in biomedical and behavioural research. However, because of their highly developed cognitive abilities and social skills, the use of these animals in biomedical research is debated more and more. Although it is acknowledged that in specific research areas NHP are still essential, it is recognised that the use of these animals can only be done under strict conditions under the most optimal welfare aspects. Welfare aspects include housing conditions, non-invasive methods and application of the 3Rs policy. Although many refinement methods have been described in nationally and internationally accepted guidelines on animal laboratory practice, recognition of the guidelines is unfortunately not universal. The present book covers a wide range of NHP models in preclinical research and welfare issues. The following chapters will cover: refinement of the use of NHP in biomedical research; NHP ethics and regulations in Europe; biological basis differences in the human and NHP; the major histocompatibility complex (MHC) immunology in NHP; stem cell biology in NHP; neuro and gliogenesis in an NHP ischemia stroke model; NHP models in autoimmune disease, organ transplantation and infectious disease research; viral diseases in NHP; NHP models in Parkinsons disease, in neurodegenerative disorders research and in cardio-cerebrovascular disease research; islet transplantation; ophthalmic diseases research and neurophysiology in NHP; transgenic engineering in NHP; NHP models of cancers; NHP models in respiratory disease research; NHP models in clinical and non-clinical pharmacology; NHP models in lung transplantation; and aging research in NHP. This book encapsulates a large volume of knowledge scientists have achieved in the field of nonhuman primate models in preclinical research. The editors have invited experts from the United States, Canada, and Europe to contribute 23 chapters in their respective fields of their expertise.
Автор: Bennett L. Schwartz, Michael J. Beran Название: Primate Cognitive Studies ISBN: 1108845436 ISBN-13(EAN): 9781108845434 Издательство: Cambridge Academ Рейтинг: Цена: 16474.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides comprehensive and up-to-date chapters from experts on the cognition of non-human primates, and describes how primate cognition is studied in labs, zoos, sanctuaries, and in the field. It analyses issues of replicability, open-access, and ethics, with strong emphasis on comparative approaches.
Автор: Diogo, Rui Название: Muscles of Vertebrates ISBN: 1578086825 ISBN-13(EAN): 9781578086825 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Wagele J. Wolfgang Название: Deep Metazoan Phylogeny: the Backbone of the Tree of Life ISBN: 3110277468 ISBN-13(EAN): 9783110277463 Издательство: Walter de Gruyter Цена: 27884.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The growing success of molecular methods has challenged traditional views of animal evolution and a large number of alternative hypotheses are hotly debated today. For the deep metazoan phylogeny project, data sets of hitherto unmatched quality and quantity were compiled and analysed with innovative bioinformatics tools. The book begins at the base of the tree of life to discuss the origin of animals and early branches of the phylogenetic tree. The following section presents special data sets gained from mitochondrial genomes and from morphology, with a focus on nervous systems. The final section is dedicated to theoretical aspects of data analysis and new bioinformatics tools. The book closes with a unique general discussion of all hypotheses contained in previous chapters. This work provides the most comprehensive overview available of the state of the art in this exciting field of evolutionary research.
Annelida, mainly consisting of marine Polychaeta and in faunal and partly parasitic Clitellata, is one the most significant metazoan taxa. Its more than 20.000 described species invade nearly all habitats and play a central role in marine benthic systems as well as in terrestrial soil communities. Annelids include all soft-bodied segmented worm-like organisms and have been recognized as a separate "phylum" for almost 200 years.
Recently, evidence has been accumulated which shows that some of the groups formerly regarded as independent "phyla" such as Pogonophora (now recognized as Siboglinidae), Echiura, Myzostomida and perhaps Sipuncula, are most probably nothing else than greatly modified Annelida. The extreme morphological diversity found especially in Polychaeta displays the plasticity of a simple segmented organisation that basically is nothing else but a serial repetition of identical units. Thus, annelids are highly important to our understanding of fundamental questions about morphological and adaptive diversity, as well as clarifying evolutionary changes and phylogenetic relationships.
The book aims to summarize our knowledge on Polychaetes polychaetes and their allies and gives an overview of recent advances gained by studies that employed conventional and modern methods plus, increasingly and importantly, the use of molecular markers and computer-assisted kinship analyses. It also reflects the state of art in polychaete sciences and presents new questions and controversies. As such it will significantly influence the direction of research on Polychaeta and their related taxa.
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