Specific Gene Expression and Epigenetics, Ayyanathan, Kasirajan
Автор: Ferguson, Bradley Название: Ferguson-NUTRITIONAL EPIGENOMICS ISBN: 0128168439 ISBN-13(EAN): 9780128168431 Издательство: Elsevier Science Рейтинг: Цена: 26444.00 р. Наличие на складе: Поставка под заказ.
Описание:
Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition's role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet's role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders.
Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease.
Empowers the reader to employ nutritional epigenomics approaches in their own research
Discusses the latest topics in nutritional epigenomics in the regulation of aging, circadian rhythm, inheritance and fetal development, as well as metabolism and disease
Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies
Автор: Johannes Backs, Timothy McKinsey Название: Epigenetics in Cardiac Disease ISBN: 3319414550 ISBN-13(EAN): 9783319414553 Издательство: Springer Рейтинг: Цена: 14673.00 р. 20962.00-30% Наличие на складе: Есть (1 шт.) Описание: This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.
Автор: Naumova Anna K & Taketo-Hosotani Teruko Название: Epigenetics In Human Reproduction And Development ISBN: 9813144262 ISBN-13(EAN): 9789813144262 Издательство: World Scientific Publishing Цена: 18216.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood.
Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.
This title includes a number of Open Access chapters.
This new volume on gene expression and epigenetics discusses environmental effects related to specific gene expression. The book also shows methods for bioinformatic analysis of the epigenome. The book is broken into two sections: the first looks at eukaryotic DNA methylation and the second addresses how to integrate genomic medicine into clinical practice.
The book includes chapters on these topics:
- Gene expression in colon cancer tissue
- Epigenetics in human acute kidney injury
- Embryologically relevant candidate genes in MRKH patients
- DNA methylation in common skeletal disorders
- Causal relationships in genomics
- Predicting severe asthma exacerbations in children
- Epigenetic understanding of gene-environment interactions in psychiatric disorders
You Are About To Develop A Comprehensive Understanding Of The Concept Of Epigenetics, Its Place In Modern Day Medicine, And Health Optimization And Why It Is Literally Changing How We Approach The Treatment Of Various Health Problems
Here is a bit of what you'll learn from this 2 in 1 book:
- What epigenetics are, why they're important and how they work
- How epigenetics relate with our experiences
- How cells divide, and how genes control the growth and division of cells
- The difference between the DNA, gene and chromosomes
- The existing evidence of epigenetic changes, including in transgenerational epigenetic inheritance
- The ins and outs of epigenetics mechanisms
- The types of epigenetic therapies available today, including their risks, benefits and research on them
- The effect of epigenetic control in transcriptional regulation in pluripotency and early differentiation, DNA methylation and Demethylation, nucleosome remodeling and chromatin looping
- How epigenetics work at the molecular level and the effect of DNA damage in epigenetic change
- The functions of epigenetics, and how they boost mindfulness training, healthy eating and exercise
- How epigenetic therapy and modifications affects diabetic retinopathy, emotional disorders, cardiac dysfunction, cancer and schizophrenia, mesothelioma and many more
- How epigenetic modifications are used in understanding plant and animal evolution
- How epigenetic mechanisms are used in understanding human adaptation, boosting memory formation, growth and reinforcing infant neurobehavior.
- The role of epigenetic mechanisms in maternal care
- The role of environmental chemicals in epigenetics
- How epigenetics are involved in neurodegenerative diseases, drug formation, human development, the development of Hox genes and many more.
- The role of environmental exposures in pathophysiology of IPF
- Modulation of epigenetic marks by environmental exposures
- How epigenetic regulation affects the immune system
...And so much more
Whether you are a beginner or an intermediate in epigenetics, you will find this book educative, as you learn the A-Z of factors that are quickly changing our understanding of the structure of life.
Don't wait....
Автор: Moskalev, Alexey Название: Epigenetics of Aging and Longevity ISBN: 0128110600 ISBN-13(EAN): 9780128110607 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Поставка под заказ.
Описание:
Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses--including cancer and cardiovascular, metabolic, and neurodegenerative diseases--are explored in detail.
This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease.
You Are About To Develop A Comprehensive Understanding Of The Concept Of Epigenetics, Its Place In Modern Day Medicine, And Health Optimization And Why It Is Literally Changing How We Approach The Treatment Of Various Health Problems
Here is a bit of what you'll learn from this 2 in 1 book:
- What epigenetics are, why they're important and how they work
- How epigenetics relate with our experiences
- How cells divide, and how genes control the growth and division of cells
- The difference between the DNA, gene and chromosomes
- The existing evidence of epigenetic changes, including in transgenerational epigenetic inheritance
- The ins and outs of epigenetics mechanisms
- The types of epigenetic therapies available today, including their risks, benefits and research on them
- The effect of epigenetic control in transcriptional regulation in pluripotency and early differentiation, DNA methylation and Demethylation, nucleosome remodeling and chromatin looping
- How epigenetics work at the molecular level and the effect of DNA damage in epigenetic change
- The functions of epigenetics, and how they boost mindfulness training, healthy eating and exercise
- How epigenetic therapy and modifications affects diabetic retinopathy, emotional disorders, cardiac dysfunction, cancer and schizophrenia, mesothelioma and many more
- How epigenetic modifications are used in understanding plant and animal evolution
- How epigenetic mechanisms are used in understanding human adaptation, boosting memory formation, growth and reinforcing infant neurobehavior.
- The role of epigenetic mechanisms in maternal care
- The role of environmental chemicals in epigenetics
- How epigenetics are involved in neurodegenerative diseases, drug formation, human development, the development of Hox genes and many more.
- The role of environmental exposures in pathophysiology of IPF
- Modulation of epigenetic marks by environmental exposures
- How epigenetic regulation affects the immune system
...And so much more
Whether you are a beginner or an intermediate in epigenetics, you will find this book educative, as you learn the A-Z of factors that are quickly changing our understanding of the structure of life.
Автор: Ayyanathan, Kasirajan Название: Epigenetics and Pathology ISBN: 1774633051 ISBN-13(EAN): 9781774633052 Издательство: Taylor&Francis Рейтинг: Цена: 12707.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
This title includes a number of Open Access chapters.
This important book explores recent research by experts in the field pertaining to the role played by genetic factors in human pathology. A range of perspectives creates a well-rounded picture, including:
host-pathogen interactions
causal relationships between genes and the environment
the effects of environmental chemicals on gene expression
DNA methylation
The book also covers the analysis and provides models for understanding the epigenetics-pathology connection.
This book is designed for use by senior undergraduate and graduate students from several disciplines such as general, molecular, cellular biology, genetics, genomics, proteomics, and bioinformatics. It will also serve as a reference book for existing researchers and new investigators entering this rather unexplored field.
Автор: Boosani, Chandra S. Название: Epigenetics In Organ Specific Disorders,34 ISBN: 012823931X ISBN-13(EAN): 9780128239315 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This completely updated second edition includes case studies and a focus on the business of system operations. The broad range of actions under system operations from transmission to distribution are explored. The underpinnings of electric systems operations are highlighted, with an introduction to utilities and power systems. It offers a thorough definition of system operations, identifying and explaining the various systems that support this function and how they integrate into the utility.The book presents a thorough definition of system operations, identifying and explaining the various systems that support this function and how they integrate into the utility. The business perspective on electric systems operation, and how critical this area is to a utility`s ability to provide reliable power to customers is detailed. Readers discover how a utility`s network operation is a key contributor to the viable sustainment of its business. The book presents the convergence of the systems used in the grid operations of today and addresses the emerging needs of the smart grid operations of tomorrow. Readers discover how a utility`s network operation is a key contributor to the viable sustainment of its business, as well as learn how system operations help to ensure the right levels of safety, reliability and efficiency in everything that relates to transmission and distribution grid management.
Название: Post-transcriptional gene regulation in human disease ISBN: 0323913059 ISBN-13(EAN): 9780323913058 Издательство: Elsevier Science Рейтинг: Цена: 22738.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Let`s Learn About the Forest is an interactive oversized board book that encourages little ones to use their imaginations and power of discovery to find the different animals and items in the forest God created. As they do, they will also learn interesting facts about the different animals and their habitats.
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