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Biology of Death: Origins of Mortality, Andre Klarsfeld, Frederic Revah


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Автор: Andre Klarsfeld, Frederic Revah
Название:  Biology of Death: Origins of Mortality
ISBN: 9780801441189
Издательство: Wiley EDC
Классификация:

ISBN-10: 0801441188
Обложка/Формат: Hardback
Страницы: 240
Вес: 0.47 кг.
Дата издания: 2003-10-16
Язык: English
Иллюстрации: Charts
Размер: 233 x 162 x 20
Читательская аудитория: Undergraduate
Основная тема: Biology, life sciences,Geriatric nursing, MEDICAL / Nursing / Gerontology,MEDICAL / Nursing / Oncology & Cancer,SCIENCE / Life Sciences / Biology
Подзаголовок: Origins of mortality
Ссылка на Издательство: Link
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Поставляется из: Англии
Описание: Why do we die? Do all living creatures share this fate? Is the bodys slow degradation with the passage of time unavoidable, or can the secrets of longevity be unlocked? Over the past two decades, scientists studying the workings of genes and cells have uncovered some of the clues necessary to solve these mysteries. In this fascinating and accessible book, two neurobiologists share the often-surprising findings from that research, including the possibility that aging and natural death may not be forever a certainty for most living beings. Andr? Klarsfeld and Fr?d?ric Revah discuss in detail the latest scientific findings and views on death and longevity. They challenge many popular assumptions, such as the idea that the death of individual organisms serves to rejuvenate species or that death and sexual reproduction are necessarily linked. Finally, they describe current experimental approaches to postpone natural death in lower organisms as well as in mammals. Are all organisms that survive until late in life condemned to a natural death, as a consequence of aging, even if they live in a well-protected, supportive environment? The variability of the adult life span—from a few hours for some insects to more than a millennium for the sequoia and thirteen times that for certain wild berry bushes—challenges the notion that death is unavoidable. Evolutionary theory helps explain why and how some species have achieved biological mechanisms that seemingly allow them to resist time. Death cannot be understood without looking into cells—the essential building blocks of life. Intriguingly, at the level of cells, death is not always an accident; it is often programmed as an indispensable aspect of life, which benefits the organism as a whole.


Epidemiology:  Key to Public Health. 2 ed.

Автор: Krickeberg Klaus, Van Trong Pham, Thi My Hanh Pham
Название: Epidemiology: Key to Public Health. 2 ed.
ISBN: 3030163679 ISBN-13(EAN): 9783030163679
Издательство: Springer
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Цена: 13974.00 р.
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Описание: ?This unique textbook presents the field of modern epidemiology as a whole; it does not restrict itself to particular aspects. It stresses the fundamental ideas and their role in any situation of epidemiologic practice. Its structure is largely determined by didactic viewpoints.Epidemiology is the art of defining and investigating the influence of factors on the health of populations. Hence the book starts by sketching the role of epidemiology in public health. It then treats the epidemiology of many particular diseases; mathematical modelling of epidemics and immunity; health information systems; statistical methods and sample surveys; clinical epidemiology including clinical trials; nutritional, environmental, social, and genetic epidemiology; and the habitual tools of epidemiologic studies. The book also reexamines the basic difference between the epidemiology of infectious diseases and that of non-infectious ones.The organization of the topics by didactic aspects makes the book ideal for teaching. All examples and case studies are situated in a single country, namely Vietnam; this provides a particularly vivid picture of the role of epidemiology in shaping the health of a population. It can easily be adapted to other developing or transitioning countries.This volume is well suited for courses on epidemiology and public health at the upper undergraduate and graduate levels, while its specific examples make it appropriate for those who teach these fields in developing or emerging countries. New to this edition, in addition to minor revisions of almost all chapters:• Updated data about infectious and non-infectious diseases• An expanded discussion of genetic epidemiology• A new chapter, based on recent research of the authors, on how to build a coherent system of Public Health by using the insights provided by this volume.

Dictionary of Biology

Автор: Hine Michael
Название: Dictionary of Biology
ISBN: 0198821484 ISBN-13(EAN): 9780198821489
Издательство: Oxford Academ
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Цена: 2533.00 р.
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Описание: This new eighth edition has been fully updated to reflect recent progress in the fields of biology, biophysics, and biochemistry. Now with over 5,600 entries, over 120 new to this edition, the dictionary sees wider coverage of such areas as ecology and plant and animal development, as well as updated appendices, web links, and diagrams.

The Music of Life: Biology Beyond the Genome

Автор: Noble, Denis
Название: The Music of Life: Biology Beyond the Genome
ISBN: 0199295735 ISBN-13(EAN): 9780199295739
Издательство: Oxford Academ
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Цена: 5146.00 р.
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Описание: What is life? Addressing this question, this lyrical book views that the genome is not life itself: to understand what life is, we must view it at a variety of different levels, all interacting with each other in a complex web. It is that emergent web, full of feedback between levels, from the gene to the wider environment, that is life.

Cardiac Regeneration

Автор: Masaki Ieda, Wolfram-Hubertus Zimmermann
Название: Cardiac Regeneration
ISBN: 3319561049 ISBN-13(EAN): 9783319561042
Издательство: Springer
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Цена: 14673.00 р. 20962.00 -30%
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This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair.

Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged.

The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Philosophy of Systems Biology

Автор: Sara Green
Название: Philosophy of Systems Biology
ISBN: 3319469991 ISBN-13(EAN): 9783319469997
Издательство: Springer
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Цена: 13974.00 р.
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Описание: The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology? To what extent is the use of mathematical and computational modelling changing the life sciences? How does the availability of big data influence research practices? What are the major challenges for biomedical research in the years to come? This book addresses such questions of relevance not only to philosophers and biologists but also to readers interested in the broader implications of systems biology for science and society.The book features reflections and original work by experts from across the disciplines including systems biologists, philosophers, and interdisciplinary scholars investigating the social and educational aspects of systems biology. In response to the same set of questions, the experts develop and defend their personal perspectives on the distinctive character of systems biology and the challenges that lie ahead. Readers are invited to engage with different views on the questions addressed, and may explore numerous themes relating to the philosophy of systems biology.This edited work will appeal to scholars and all levels, from undergraduates to researchers, and to those interested in a variety of scholarly approaches such as systems biology, mathematical and computational modelling, cell and molecular biology, genomics, systems theory, and of course, philosophy of biology.

Cellular Biophysics and Modeling: A Primer on the Computational Biology of Excitable Cells

Автор: Greg Conradi Smith
Название: Cellular Biophysics and Modeling: A Primer on the Computational Biology of Excitable Cells
ISBN: 1107005361 ISBN-13(EAN): 9781107005365
Издательство: Cambridge Academ
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Цена: 15046.00 р.
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Описание: What every neuroscientist should know about the mathematical modeling of excitable cells. Combining empirical physiology and nonlinear dynamics, this text provides an introduction to the simulation and modeling of dynamic phenomena in cell biology and neuroscience. It introduces mathematical modeling techniques alongside cellular electrophysiology. Topics include membrane transport and diffusion, the biophysics of excitable membranes, the gating of voltage and ligand-gated ion channels, intracellular calcium signalling, and electrical bursting in neurons and other excitable cell types. It introduces mathematical modeling techniques such as ordinary differential equations, phase plane, and bifurcation analysis of single-compartment neuron models. With analytical and computational problem sets, this book is suitable for life sciences majors, in biology to neuroscience, with one year of calculus, as well as graduate students looking for a primer on membrane excitability and calcium signalling.

Brain Death and Disorders of Consciousness

Автор: Calixto Machado; D. Alan Shewmon
Название: Brain Death and Disorders of Consciousness
ISBN: 1475709765 ISBN-13(EAN): 9781475709766
Издательство: Springer
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Цена: 25155.00 р.
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Описание: Although some decades have passed, there are still worldwide controversies about a concept of human death on neurological grounds. The main goal of Brain Death and Disorders of Consciousness is to provide a suitable scientific platform to discuss all topics related to human death and coma.

Programmed Cell Death

Автор: Hamsa Puthalakath; Christine J. Hawkins
Название: Programmed Cell Death
ISBN: 1493935798 ISBN-13(EAN): 9781493935796
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume containsprotocols specifically designed for studying programmed cell death, and alsodiscusses recent advances in techniques that span broader areas of biology thathave been recently used or that have potential to be incorporated into cell deathresearch.

Neuronal Cell Death

Автор: Laura Lossi; Adalberto Merighi
Название: Neuronal Cell Death
ISBN: 1493944649 ISBN-13(EAN): 9781493944644
Издательство: Springer
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Цена: 15372.00 р.
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Описание:

1. Neuronal Cell Death: An Overview of its Different Forms in Central and Peripheral Neurons

Laura Lossi, Claudia Castagna, and Adalberto Merighi

Part I: Molecular, Sturctural, Functional, and Genomic Changes in Dying Neurons2. Cell Volume Regulation Monitored with Combined Epifluorescence and Digital Holographic MicroscopyNicolas Pavillon and Pierre Marquet

3. Flow Cytometric Analysis of DNA Synthesis and Apoptosis in Central Nervous System Using Fresh Cell Nuclei

Noelia Lуpez-Sбnchez and Josй M. Frade

4. Nuclear Signs of Pre-Neurodegeneration

Fernando C. Baltanбs, Jorge Valero, Jose Ramуn Alonso, Maria Teresa Berciano, and Miguel Lafarga

5. Multi-Parametric O2 Imaging in Three-Dimensional Neural Cell Models with the Phosphorescent Probes

Ruslan I. Dmitriev and Dmitri B. Papkovsky

6. Calcium Imaging in Neuron Cell Death

Marнa Calvo, Carlos Villalobos, and Lucнa Nъсez

7. Monitoring Mitochondrial Membranes Permeability in Live Neurons and Mitochondrial Swelling through Electron Microscopy Analysis

Macarena S. Arrбzola and Nibaldo C. Inestrosa

8. Real-Time Visualization of Caspase-3 Activation by Fluorescence Resonance Energy Transfer (FRET)

Silvia Alasia, Carolina Cocito, Adalberto Merighi, and Laura Lossi

9. Design and Cloning of Short Hairpin RNAs (shRNAs) into a Lentiviral Silencing Vector to Study the Function of Selected Proteins in Neuronal Apoptosis

Nadia Canu

10. Genomic Analysis Using Affymetrix Standard Microarray GeneChips (169 Format) in Degenerate Murine Retina

Sook Hyun Chung, Weiyong Shen, and Mark Gillies

11. Genomic Analysis of Transcriptional Changes Underlying Neuronal Apoptosis

Sebastiano Cavallaro

12. High-Throughput Cell Death Assays

Matthew E. Pamenter and Gabriel G. Haddad

PartII: Cell Death in Neuropathology and Experimental Neuoropathology

13. Staining of Dead Neurons by the Golgi Method in Autopsy Material

Stavros J. Baloyannis

14. Image Analysis Algorithms for Immunohistochemical Assessment of Cell Death

Stan Krajewski, Jeffrey Wang, Tashmia Khan, Jonathan Liu, Chia-Hung Sze, and Maryla Krajewska

15. In Vitro Oxygen-Glucose Deprivation to Study Ischemic Cell Death

Carla I. Tasca, Tharine Dal-Cim, and Helena Cimarosti

16. Laser Microbeam Targeting of Single Nerve Axons in Cell Culture

Nicholas Hyun, Linda Z. Shi, and Michael W. Berns

17. Real-Time Imaging of Retinal Cell Apoptosis by Confocal Scanning Laser Ophthalmoscopy

Eduardo M. Normando, Mohammad H. Dehabadi, Li Guo, Lisa A. Turner, Gaia Pollorsi, and M. Francesca Cordeiro

18. Targeted Toxicants to Dopaminergic Neuronal Cell Death

Huajun Jin, Arthi Kanthasamy, Dilshan S. Harischandra, Vellareddy Anantharam, Ajay Rana, and Anumantha G. Kanthasamy

Part III: Neural Stem Cells, Progenitors, and Gene Therapy Strategies

19. Stem Cells, Neural Progenitors, and Engineered Stem Cells

Raj R. Rao and Shilpa Iyer

20. Herpes Simplex Virus Type 1 (HSV-1)-Derived Recombinant Vectors for Gene Transfer and Gene Therapy

Peggy Marconi, Cornel Fraefel, and Alberto L. Epstein

21. Herpes Simplex Virus Type 1 (HSV-1)-Derived Amplicon Vectors for Gene Transfer and Gene Therapy

Cornel Fraefel, Peggy Marconi, and Alberto L. Epstein

22. Bone Marrow Transplantation for Research and Regenerative Therapies in the Central Nervous System

David Dнaz, Josй Ramуn Alonso, and Eduardo Weruaga

Part IV: Neuronal Death in Non Mammalian Models

23. Detection of Activated Caspase-8 in Injured Spinal Axon

Programmed Cell Death

Автор: Hamsa Puthalakath; Christine J. Hawkins
Название: Programmed Cell Death
ISBN: 149398084X ISBN-13(EAN): 9781493980840
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This volume containsprotocols specifically designed for studying programmed cell death, and alsodiscusses recent advances in techniques that span broader areas of biology thathave been recently used or that have potential to be incorporated into cell deathresearch.

The Evolutionary Origins of Life and Death

Автор: Durand Pierre M.
Название: The Evolutionary Origins of Life and Death
ISBN: 022674776X ISBN-13(EAN): 9780226747767
Издательство: Wiley
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Цена: 4910.00 р.
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Описание: This book is a comprehensive practical guide for music eductors who work with students with autism. This second edition offers fully up-to-date information on diagnosis, advocacy, and a collegial team-approach, as well as communication, cognition, behavior, sensory, and socialization challenges. Many `real-life` vignettes and classroom snapshots are included to transfer theory to practice.

Brain Death and Disorders of Consciousness

Автор: Machado Calixto, Shewmon D. Alan
Название: Brain Death and Disorders of Consciousness
ISBN: 030648482X ISBN-13(EAN): 9780306484827
Издательство: Springer
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Цена: 36570.00 р.
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Описание: Although some decades have passed, there are still worldwide controversies about a concept of human death on neurological grounds. There are also disagreements on the diagnostic criteria for brain death, whether clinical alone or clinical plus ancillary tests. Moreover, some scholars who were strong defenders of a brain-based standard of death are now favoring a circulatory-respiratory standard. The study of coma is extremely important because lesions of the brain are responsible for quality of life in patients or cause of death. The main goal of Brain Death and Disorders of Consciousness is to provide a suitable scientific platform to discuss all topics related to human death and coma.


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