Название: G Protein-Coupled Receptors: From Structure to Function ISBN: 1849731837 ISBN-13(EAN): 9781849731836 Издательство: Royal Society of Chemistry Рейтинг: Цена: 26926.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book considers the relationship between structure and function in G protein-coupled receptors (GPCRs) and the implications for drug design.
Автор: Shukla, Arun K. Название: G Protein-Coupled Receptors - Part B,195 ISBN: 0323994342 ISBN-13(EAN): 9780323994347 Издательство: Elsevier Science Рейтинг: Цена: 20043.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Now firmly established as one of the leading economics principles texts in the UK and Europe, the sixth edition of Macroeconomics has been fully updated. Much revered for its friendly and accessible approach, emphasis on active learning and unrivalled support resources, this edition features a brand-new chapter on sustainability economics as well as in depth coverage of the impact of globalization, digitization, the gig economy and modern monetary theory.This title is available with MindTap, a flexible online learning solution that provides students with all the tools they need to succeed including an interactive eReader, engaging multimedia, practice questions, assessment materials, revision aids, and analytics to help you track their progress.
Автор: Bruce G. Allen; Terence E. H?bert Название: Nuclear G-Protein Coupled Receptors ISBN: 1493955462 ISBN-13(EAN): 9781493955466 Издательство: Springer Рейтинг: Цена: 13275.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Nuclear G-Protein Coupled Receptors: Methods and Protocols is a compilation of a number of conceptual and methodological aspects important for the validation and characterization of intacrine signaling systems.
Автор: Marta Filizola Название: G Protein-Coupled Receptors - Modeling and Simulation ISBN: 9400774222 ISBN-13(EAN): 9789400774223 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses.
Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scientific importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine β-synthase, and Oligomerization of Porphobilinogen Synthase.
Автор: Langenhan Название: Adhesion G Protein-coupled Receptors ISBN: 3319823752 ISBN-13(EAN): 9783319823751 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Нет в наличии.
Описание: Latest research on Adhesion GPCRs has unearthed surprising revelations about the events that govern the signal transduction of these receptor molecules and the cellular and organ requirements for these signals. Unexpected and unprecedented findings suggest that Adhesion GPCRs constitute a group of receptors that sense mechanical stimuli and transcode them into metabotropic signals through the action of a novel activation paradigm. Interdisciplinary efforts transcending many areas of biomedical research including pharmacology, physiology, genetics, cell biology, structural biology, biochemistry and bioinformatics were necessary to unveil these fundamental properties. The scientific leaders in the field that carried this research effort have teamed up here to provide a comprehensive overview of our current understanding, how Adhesion GPCRs signal and how these receptors shape organ structure and function.
Автор: Marta Filizola Название: G Protein-Coupled Receptors - Modeling and Simulation ISBN: 9402402586 ISBN-13(EAN): 9789402402582 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses.
Автор: Bruce G. Allen; Terence E. H?bert Название: Nuclear G-Protein Coupled Receptors ISBN: 1493917544 ISBN-13(EAN): 9781493917549 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Nuclear G-Protein Coupled Receptors: Methods and Protocols is a compilation of a number of conceptual and methodological aspects important for the validation and characterization of intacrine signaling systems.
Название: G Protein-Coupled Receptors in Drug Discovery ISBN: 0367392518 ISBN-13(EAN): 9780367392512 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Нет в наличии.
Описание:
The broad range of G protein-coupled receptors (GPCRs) encompasses all areas of modern medicine and have an enormous impact on the process of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled Receptors in Drug Discovery describes the physiological roles of GPCRs and their involvement in various human diseases.
The book presents current approaches in drug discovery that include target selection, establishment of screening and functional assays. It also covers recombinant GPCR expression for drug screening and structural biology, different methods for structural characterization of GPCRs, and the importance of bioinformatics. The book has been carefully edited to avoid overlapping information, some duplication has been intentionally permitted so that each chapter can function as an independent unit. Providing in-depth discussions on structure and dynamics of GPCRs, this book outlines the importance of the GPCRs to drug discovery in general and drug targets specifically.
Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.
Автор: Shukla, Arun K. Название: G Protein-Coupled Receptors - Part A,193 ISBN: 0323994318 ISBN-13(EAN): 9780323994316 Издательство: Elsevier Science Рейтинг: Цена: 20043.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Duarte Miguel F. Prazeres; Sofia Aires M. Martins Название: G Protein-Coupled Receptor Screening Assays ISBN: 1493923358 ISBN-13(EAN): 9781493923359 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume explores the considerable efforts that have been directed towards the development of G Protein-Coupled Receptors (GPCR) screening assays in order to disclose GPCR acting compounds, elucidate signaling mechanisms or evaluate compound`s efficacy.
Автор: Mark P. Running Название: G Protein-Coupled Receptor Signaling in Plants ISBN: 1627035311 ISBN-13(EAN): 9781627035316 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology book describes techniques used in the study of small GTPases and related proteins. Includes a chapter on bioinformatics approaches, plus reproducible protocols, materials lists, practical tips and troubleshooting advice.
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