Автор: Jessup M. Shively Название: Complex Intracellular Structures in Prokaryotes ISBN: 3642068936 ISBN-13(EAN): 9783642068935 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The new series "Microbiology Monographs" begins with two volumes on intracellular components in prokaryotes. In this second volume, "Complex Intracellular Structures in Prokaryotes", the components, labeled complex intracellular structures, encompass a multitude of important cellular functions.
Автор: Donev, Rossen Название: Intracellular Signalling Proteins ISBN: 0128155612 ISBN-13(EAN): 9780128155615 Издательство: Elsevier Science Рейтинг: Цена: 17517.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Intracellular Signalling Proteins, Volume 116, presents an overview of the current developments in mechanisms of intracellular signaling and involvement of these mechanisms in the development of a number of disorders and diseases. Opportunities for targeting the intracellular signaling cascades for benefiting patients are also discussed, along with chapters that focus on Voices from the Dead: The Complex Language of Dead Cells, Nucleobindins and Encoded Peptides: From Cell Signalling to Physiology, Estrogen Receptor Signaling Mechanisms, Intracellular Signaling of the AMP-Activating Protein Kinase, the Relationship between Mitofusin 2 and Cancer, Molecular Signaling in Bone Cells: Regulation Cell Differentiation and Survival, and more.
Describes advances in the discovery and application of therapeutics that target intracellular signaling mechanisms
Targeted to a very wide audience of specialists, researchers and students
Contains timely chapters written by well-renowned authorities in their field
Includes a number of high quality illustrations, figures and tables
Автор: Danielle Pansu; Felix Bronner Название: Calcium Transport and Intracellular Calcium Homeostasis ISBN: 3642839797 ISBN-13(EAN): 9783642839795 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Calcium Transport and Intracellular Calcium Homeostasis held in Lyon, France, March 4-7, 1990
Автор: Martin Morad; Zalman Agus Название: Intracellular Regulation of Ion Channels ISBN: 3642846300 ISBN-13(EAN): 9783642846304 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Intracellular Modulation of Cardiac and Neuronal Ion Channels at Il Ciocco, Lucca (Italy) from April 26-30, 1991
Автор: Maria C. Pedroso De Lima; Nejat D?zg?nes; Dick Hoe Название: Trafficking of Intracellular Membranes: ISBN: 3642795498 ISBN-13(EAN): 9783642795497 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Study Institute "Traficking of Intracellular Membranes: From Molecular Sorting to Membrane Fusion", held at Espinho, Portugal, June 19 - 30, 1994
Название: Plant carbohydrates i ISBN: 3642682774 ISBN-13(EAN): 9783642682773 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Jos?-Luis Avila; J. Robin Harris Название: Intracellular Parasites ISBN: 1489916539 ISBN-13(EAN): 9781489916532 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Volume 18 of the Subcellular Biochemistry series, which specializes in various aspects of the biochemistry of the intracellular parasites, was initially proposed by Jose Luis Avila and strongly supported by myself, as Series Editor of Sub- cellular Biochemistry.
Автор: Antonino Cattaneo; Silvia Biocca Название: Intracellular Antibodies ISBN: 3662079941 ISBN-13(EAN): 9783662079942 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells.
Автор: Herwig J. Hilderson Название: Subcellular Biochemistry ISBN: 1489916237 ISBN-13(EAN): 9781489916235 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Korotkov, Sergey (leading Researcher, Russian Academy Of Sciences, Sechenov Institute Of Evolutionary Physiology And Biochemistry, St. Petersburg, Rus Название: Mitochondria as a key intracellular target of thallium toxicity ISBN: 0323955312 ISBN-13(EAN): 9780323955317 Издательство: Elsevier Science Рейтинг: Цена: 21391.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Let`s Learn About the Forest is an interactive oversized board book that encourages little ones to use their imaginations and power of discovery to find the different animals and items in the forest God created. As they do, they will also learn interesting facts about the different animals and their habitats.
Автор: Guillaume Drin Название: Intracellular Lipid Transport ISBN: 1493991353 ISBN-13(EAN): 9781493991358 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed book provides technical approaches to tackle a variety of questions related to intracellular lipid transport in order to improve our understanding at different scales of how lipids are accurately displaced between organelles, across long distances or at membrane contact sites, or within cellular membranes. The volume begins with methodologies to measure the movement of varied lipid species between or in organelle membranes, inside eukaryotic cells, including plant cells, or in bacteria, and continues in vitro or in silico approaches aiming to define, more from a biochemical and structural standpoints, how lipid transfer proteins (LTPs) or flippases/scramblases precisely function. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Intracellular Lipid Transport: Methods and Protocols serves as an ideal guide for researchers seeking to shed light on diverse aspects of this critical and often elusive cellular process.
Автор: Padma V. Devarajan; Prajakta Dandekar; Anisha A. D Название: Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis ISBN: 3030291677 ISBN-13(EAN): 9783030291679 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book elaborates on drug delivery targeting via intracellular delivery, specifically through the Receptor Mediated Endocytosis (RME) approach, due to the involvement of cellular receptors in various grave diseases. Targeted delivery relies on two basic approaches, passive and active targeting. While passive targeting approaches have shown great promise, the improved selectivity achieved with active targeting approaches has resulted in significantly higher efficacy. Interestingly there are numerous strategies for active targeting, many of which are already highlighted in , Targeted Drug Delivery: Concepts and Applications. Nevertheless an exciting and practical strategy for active targeting, which could enable high intracellular delivery, is through exploitation of RME. Cells in the body express receptors to enable various physiological and biochemical processes. As a result, many of these receptors are overexpressed in pathological conditions, or newer receptors expressed due to defective cellular functioning. RME is based on exploitation of such receptors to achieve intracellular delivery. While targeted delivery can have manifold applications, in this book we focus on two major and challenging therapeutic areas; i) Cancer and ii) Infectious Diseases. Targeted Intracellular Drug Delivery by Receptor Medicated Endocytosis discusses the major receptors that are useful for targeted delivery for these afflictions. A major section of this book is dedicated to details regarding their occurrence and location, the recognition domain of the receptor, structure activity relationship of substrate /ligand for selective binding, ligands explored, antagonists for ligand binding and relevance of these aspects for therapy of cancer and infectious diseases. These facets are elucidated with the help of specific examples from academic research and also emphasize commercial products, wherever relevant. In vitro cellular models relied on for assessing receptor mediated cellular targeting and in vivo models depicting clinical efficacy are focused on in a separate section. Finally, we briefly discuss the regulatory and toxicity issues that may be associated specifically with the RME approach of intracellular drug delivery.
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