Global New Drug Development - An Introduction, Rosier
Автор: Iversen Les Название: Drugs: A Very Short Introduction ISBN: 0198745796 ISBN-13(EAN): 9780198745792 Издательство: Oxford Academ Рейтинг: Цена: 1582.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this second edition, Les Iversen presents an introductory account of what drugs are, how they work, and the advances made over the past 100 years in the field of pharmacology. Looking at pharmaceutical drugs and both legal and illegal recreational drugs, Iversen reflects on how twentieth-century drugs have changed our lives.
Автор: J. Rick Turner Название: New Drug Development ISBN: 1493900919 ISBN-13(EAN): 9781493900916 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Optimum quality data facilitate optimum quality statistical analysis and interpretation of the results obtained, which in turn permit optimum quality decisions to be made: Rational decision making is predicated on appropriate research questions and optimum quality numerical information.
Описание: "Drug-Receptor Thermodynamics" covers the general principles of thermodynamics and its use and utility in pharmacology; provides a review of actual applications arranged according to receptor categories; and discusses the potential for thermodynamics to some day predict drug action.
Описание: This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases.Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.
Автор: S.P. Vyas, Roop V. Khar, Sonal Vyas Название: Introduction of Novel Drug Delivery Systems ISBN: 938852781X ISBN-13(EAN): 9789388527811 Издательство: CBS India Рейтинг: Цена: 6270.00 р. Наличие на складе: Нет в наличии.
Описание: This is a useful textbook and resource for undergraduateand postgraduate students and anyone in the working concepts of a drug delivery system and its performance. A novel drug delivery system refers to strategy, technology, formulation-based approaches and customized system(s) developed for safe administration and within body transportation of drugs as needed for optimum therapeutic benefits while ensuring minimum to nil toxic effects. Multidisciplinary approaches and cutting edge technology have been used to develop the carrier modules to deliver the contained drug to the target tissues in a preprogrammed manner. The process desirably modifies the drug distribution and accumulation,thereby producing optimum therapeutic effects. Carrier-mediated drug delivery has emerged as a powerful technology for the treatment of various difficult pathologies. The therapeutic index of conventional and novel drug is enhanced owing to specificity due to targeting of drug to the particular tissue. This book includes an introduction to novel drug delivery, oral osmotic pumps, bioadhesive and mucoadhesive systems, multiple emulsions, colon-specific drug delivery systems, transdermal drug delivery systems, spherical crystallization, microemulsion, implants and inserts, micellar systems, liposomes, microspheres and microcapsules, nanoparticles,resealed erythrocytes, transfersomes and ethosomes, organogels, dendrimers, niosomes, solid lipid nanoparticles, drug conjugates, cyclodextrin complexes, multifunctional nanomedicines, and floating drug delivery system(s). Each chapter attempts to discuss introduction, concept, progress, status and future prospects of the concerned novel drug delivery system.
Автор: Gerard Marshall Raj; Ramasamy Raveendran Название: Introduction to Basics of Pharmacology and Toxicology ISBN: 9813297816 ISBN-13(EAN): 9789813297814 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Поставка под заказ.
Описание: This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.
Описание: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.
Автор: Patrick Graham Название: Introduction to Drug Synthesis ISBN: 0198708432 ISBN-13(EAN): 9780198708438 Издательство: Oxford Academ Рейтинг: Цена: 8869.00 р. Наличие на складе: Поставка под заказ.
Описание: An Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development - from the generation of novel drug structures to the improved efficiency of large scale synthesis.
Автор: Giese Matthias Название: Introduction to Molecular Vaccinology ISBN: 3319258303 ISBN-13(EAN): 9783319258300 Издательство: Springer Рейтинг: Цена: 12577.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines.
Автор: G. Gordon Gibson; Paul Skett Название: Introduction to Drug Metabolism ISBN: 0412263904 ISBN-13(EAN): 9780412263903 Издательство: Springer Рейтинг: Цена: 14365.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Although the scientific literature on drug metabolism is extensive, it suffers from the disadvantage that the material is diffuse and consists largely of specialist monographs dealing with particular aspects of the subject.
Автор: Anil Kumar Bajpai, Rajesh Saini, Abhilasha Mishra, Jaya Kumar Bajpai, Atul Tiwari Название: Stimuli-Responsive Drug Delivery Systems: From Introduction to Application ISBN: 1501518836 ISBN-13(EAN): 9781501518836 Издательство: Walter de Gruyter Цена: 14495.00 р. Наличие на складе: Нет в наличии.
Описание:
Stimuli responsive drug delivery systems have emerged as one of the most innovative classes of polymer materials of modern materials science. The book offers a convincing approach to understanding the basic principles of drug delivery process, their mathematical modeling, different types of drug delivery systems, various polymer systems responsive to stimuli such as swelling, pH, temperature, light, chemical agents, electric and magnetic fields.
Автор: Martin, Yvonne C. Название: Quantitative Drug Design ISBN: 0367384140 ISBN-13(EAN): 9780367384142 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Since the publication of the first edition, the field has changed dramatically. Scientists can now explicitly consider 3D features in quantitative structure-activity relationship (QSAR) studies and often have the 3D structure of the macromolecular target to guide the 3D QSAR. Improvements in computer hardware and software have also made the methods more accessible to scientists. Taking these developments into account, Quantitative Drug Design: A Critical Introduction, Second Edition shows scientists how to apply QSAR techniques at a state-of-the-art level.
New to the Second Edition
A new chapter on methods that identify the 3D conformations to use for 3D QSAR
New discussions on partial least squares, multidimensional scaling, clustering, support vector machines, kNN potency prediction, and recursive partitioning
Expanded case studies that include the results of data that has been re-analyzed using newer methods
A new case study on the discovery of novel dopaminergics with pharmacophore mapping and CoMFA
A new case study on the application of CoMFA to series in which the 3D structure of the ligand-protein complex is known
Based on the author's four decades of experience in all areas of ligand-based computer-assisted drug design, this invaluable book describes how to transform ligand structure-activity relationships into models that predict the potency or activity/inactivity of new molecules. It will help you avoid traps when dealing with quantitative drug design.
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