Essentials of pharmacokinetics and pharmacodynamics, Tozer, Thomas N. Rowland, Malcolm
Старое издание
Автор: Tozer Название: Introduction to Pharmacokinetics and Pharmacodynamics: The Quantitative Basis of Drug Therapy ISBN: 0781751497 ISBN-13(EAN): 9780781751490 Издательство: Lippincott Williams & Wilkins Цена: 7379.00 р. Наличие на складе: Поставка под заказ. Описание: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.
Автор: Hedaya, Mohsen A. Название: Basic Pharmacokinetics ISBN: 0367752158 ISBN-13(EAN): 9780367752156 Издательство: Taylor&Francis Рейтинг: Цена: 5511.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Kar A Название: Essentials Of Biopharmaceutics And Pharmacokinetics For Bpharm Mpharm And Research Scholars 2Ed ISBN: 9388327535 ISBN-13(EAN): 9789388327534 Издательство: CBS India Рейтинг: Цена: 3621.00 р. 5173.00-30% Наличие на складе: Есть (1 шт.) Описание: A comprehensive textbook for learning and teaching the fundamentals of biopharmaceutics along with specific focus on pharmacokinetics for BPharm and MPharm students.
Автор: K.-E. Anderson; B. Bergdahl; G. Bodem; H.J. Dengle Название: Cardiac Glycosides ISBN: 3642681689 ISBN-13(EAN): 9783642681684 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: (1970) determined an elimination half-life of 14 h in normals as com- pared to 60 h in anuric patients. They found a half-life value of 18 h in healthy individuals as compared to 68 h in anuric patients. The findings clearly in- dicate that the elimination half-life of strophanthin is prolonged in renal failure.
Автор: Wu Baojian, Lu Danyi, Dong Dong Название: Circadian Pharmacokinetics ISBN: 9811588066 ISBN-13(EAN): 9789811588068 Издательство: Springer Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book`s contents.
Описание: In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization.
Описание: Updated with the latest clinical advances, Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition, explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.
Key updates reflect advances in PK/PD as related to clinical decision making and drug research and development.
An emphasis on the clinical relevance of drugs makes the book especially applicable to pharmacy students preparing for a career in clinical practice.
Hundreds of graphs and tables provide visual representations of key pharmacokinetic/pharmacodynamic principles and effects.
More than 200 carefully written study questions, with answers and in-depth explanations, help readers enhance their conceptual understanding and learn and retain key information.
New and updated examples connect chapter content to real-world settings.
Interactive online simulations give students practice using different pharmacokinetic/pharmacodynamic models and parameters.
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Автор: Michelle A. Rudek; Cindy H. Chau; William D. Figg; Название: Handbook of Anticancer Pharmacokinetics and Pharmacodynamics ISBN: 1493938983 ISBN-13(EAN): 9781493938988 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. * Road map to anticancer drug development from discovery to NDA submission * Discussion of molecular targets and preclinical screening * Development and validation of bioanalytical methods * Chapters on clinical trial design and phase 0, I, II, III clinical trials * Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents * Review of the drug development process from both laboratory and clinical perspectives * New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development
Автор: Bobbe L. Ferraiolo; Marjorie A. Mohler; Carol A. G Название: Protein Pharmacokinetics and Metabolism ISBN: 1489923314 ISBN-13(EAN): 9781489923318 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Investigation of the pharmacokinetics and metabolism of human proteins has escalated over the last two decades because of the use of recombinant human proteins as therapeutic agents.
Автор: Peter L. Bonate; Danny R. Howard Название: Pharmacokinetics in Drug Development ISBN: 1489977996 ISBN-13(EAN): 9781489977991 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The topics chosen for this volume were selected because they are some of the current development or technological issues facing drug development project teams. They regard the practical considerations for assessment of selected special development populations. For example, they include characterization of drug disposition in pregnant subjects, for measuring arrhythmic potential, for analysis tumor growth modeling, and for disease progression modeling. Practical considerations for metabolite safety testing, transporter assessments, Phase 0 testing, and development and execution of drug interaction programs reflect current regulatory topics meant to address enhancement of both safety assessment and early decision-making during new candidate selection. Important technologies like whole body autoradiography, digital imaging and dried blood spot sample collection methods are introduced, as both have begun to take a more visible role in pharmacokinetic departments throughout the industry.
Автор: Aldo Rescigno Название: Foundations of Pharmacokinetics ISBN: 1475787391 ISBN-13(EAN): 9781475787399 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book has its origin in my experience as a teacher of pharmacokinetics in many universities in four different continents. Chapters 13 to 17 show how different parameters of importance in pharmacokinetics can be exactly defined and measured.
Описание: This book casts new light on the field of oral drug absorption. It outlines both the concept of the past and the novel concept of Finite Absorption Time (FAT). In addition, the authors explore the correlated need for re-definition of bioavailability, bioequivalence providing a plethora of experimental data. Accordingly, this book is intended for academics/students or scientists working in pharmaceutical industries, regulatory agencies, and contract research organizations. It can be used for teaching purposes in under- and post-graduate courses dealing with biopharmaceutics, pharmacokinetics and biomedical engineering.
Автор: Wu Baojian, Lu Danyi, Dong Dong Название: Circadian Pharmacokinetics ISBN: 9811588090 ISBN-13(EAN): 9789811588099 Издательство: Springer Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book`s contents.
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