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Drugs and a Methodological Compendium, Rajput


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Автор: Rajput
Название:  Drugs and a Methodological Compendium
ISBN: 9789811979514
Издательство: Springer
Классификация:




ISBN-10: 9811979510
Обложка/Формат: Hardback
Страницы: 425
Вес: 0.83 кг.
Дата издания: 08.10.2023
Язык: English
Издание: 1st ed. 2023
Иллюстрации: 48 tables, color; 1 illustrations, black and white; xv, 425 p. 1 illus.
Размер: 235 x 155
Основная тема: Chemistry
Подзаголовок: From bench to bedside
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. The book also covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines.
Дополнительное описание: Chapter 1.Computational and informatics methodologies in Drug Discovery, with focus on Natural Products.- Chapter 2.Structural biology an essential tool for Drug discovery and Development.- Chapter 3.Bioactivity guided fractionation and identification of



Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular

Автор: Eric Reid; Ian D. Wilson; J.D. Robinson
Название: Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular
ISBN: 0306429969 ISBN-13(EAN): 9780306429965
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Based on the proceedings of the forum on [title]. Discusses eicosanoids and related analytes, antiflammatory drugs, cardiovascular drugs, ace inhibitors and calcium antagonists as well as detection, identification, and instrumentation. Extensive use of drawings and graphs. Annotation copyright Book News, Inc. Portland, Or.

Techniques and Methodological Approaches in Breast Cancer Research

Автор: Jose Russo; Irma H. Russo
Название: Techniques and Methodological Approaches in Breast Cancer Research
ISBN: 1493946625 ISBN-13(EAN): 9781493946624
Издательство: Springer
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Цена: 20896.00 р.
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Описание: This volume explores the myriad of techniques and methodological approaches that are being used in breast cancer research.

Extravasation of Cytotoxic Agents

Автор: Ines Mader; Birte Twisselmann; Patrizia R. F?rst-W
Название: Extravasation of Cytotoxic Agents
ISBN: 3709116678 ISBN-13(EAN): 9783709116678
Издательство: Springer
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Цена: 19564.00 р.
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Описание: The extravasation of cytotoxic agents can result in severe local tissue damage and medical emergencies during tumour therapy. This revised compendium is intended to help clinicians assess any situation speedily and with certainty. The general section of the book includes topics such as predisposition, prevention, type of harm, general measures in handling extravasated drugs, specific antidotes, and documentation. In the 2nd edition, the scientific information contained in the general section and relating to the actual substances has been updated. The substance specific part of the book includes detailed instructions on handling more than 50 cytotoxic drugs, to initiate targeted measures. Templates for an extravasation set, overview tables, documentation sheets, and patient information, as we as a CD-ROM are included to support clinical practice. The book is the outcome of a consensus of an interdisciplinary working group that has collected and systematically reviewed all published literature on the topic.

Techniques and Methodological Approaches in Breast Cancer Research

Автор: Jose Russo; Irma H. Russo
Название: Techniques and Methodological Approaches in Breast Cancer Research
ISBN: 1493907174 ISBN-13(EAN): 9781493907175
Издательство: Springer
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Цена: 25155.00 р.
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Описание: This volume explores the myriad of techniques and methodological approaches that are being used in breast cancer research. The authors critically evaluate of the advantages and disadvantages of current methodologies, starting with the tools available for understanding the architecture of the human breast, including its tissue and cellular composition. The volume discusses the importance of functional studies in breast cancer research, especially with the help of laser capture microdissection, which allows the separation of small amounts of tissue, as well as specific cells, for biochemical analysis. In addition, the authors address methodologies including stem cell separation, which has helped in significantly understanding their role in normal breast development, but also further the understanding of breast cancer and its therapeutic management. The use of in vitro techniques and established cell lines for mechanistic studies in chemotherapeutic approaches have been invaluable will be discussed. Imaging techniques for evaluating in vitro and in vivo behavior of normal and cancerous breast tissue will be explored, as it provides a better understanding of the physiopathology of cancer. The volume will also discuss the molecular analysis of gene function in breast cancer through the transcriptomic and epigenomic profile. More importantly, the advancement of more refined techniques in sequencing will be covered. This monograph will be a comprehensive, authoritative and timely, as it addresses the emerging approaches used in breast cancer research.

The Biology Of Plant-Insect Interac

Название: The Biology Of Plant-Insect Interac
ISBN: 1498709737 ISBN-13(EAN): 9781498709736
Издательство: Taylor&Francis
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Цена: 29093.00 р.
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Описание: This book covers biochemical, genetic, and molecular perspectives of plant-insect interactions with added emphasis on bioinformatic, genomic, and transcriptome analysis; presenting the agro-ecological and evolutionary aspects of plant-insect interactions with exclusive focus on the climate change effect on the resetting of plant-insect interactions

The Sandalwood Genome

Автор: Gowda
Название: The Sandalwood Genome
ISBN: 3030933962 ISBN-13(EAN): 9783030933968
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This book is the first comprehensive compilation describing the importance of sandalwood in national and international markets, genetic resources, molecular markers, whole genome sequencing, and pathway genes involved in oil biosynthesis, aroma and fragrance. Application of various “omics” approaches in delineating genome architecture and annotation of genes is highlighted. This book comprises 10 chapters covered over 200 pages authored by the researchers involved in sandalwood genomics. The sandalwood, Santalum album is known for its unique fragrance and finest wood available for carving. Also, sandalwood is intertwined with Indian culture and it is the second most valuable and expensive tree in the world.

Statistical Approaches in Oncology Clinical Development

Автор: Roychoudhury, Satrajit
Название: Statistical Approaches in Oncology Clinical Development
ISBN: 1032338784 ISBN-13(EAN): 9781032338781
Издательство: Taylor&Francis
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Цена: 8573.00 р.
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Prostaglandins, Prostacyclin, and Thromboxanes Measurement

Автор: J.M. Boeynaems; A.G. Herman
Название: Prostaglandins, Prostacyclin, and Thromboxanes Measurement
ISBN: 9400989180 ISBN-13(EAN): 9789400989184
Издательство: Springer
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Цена: 12157.00 р.
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Описание: A Workshop Symposium on Prostaglandins, prostacyclin and thromboxanes measurement; methodological problems and clinical prospects, Nivelles, Belgium, November 15-16, 1979

Drug Studies in the Elderly

Автор: N.R. Cutler; P.K. Narang
Название: Drug Studies in the Elderly
ISBN: 1468412558 ISBN-13(EAN): 9781468412550
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Clinical trials are the most definitive tool for evaluation of the applica- bility of clinical investigations. Because of an ever-increasing elderly population, newer policies for clinical investigations are now being debated with the recognition of enhanced drug sensitivity in this special population.

Aging Research - Methodological Issues

Автор: Carmen Garc?a-Pe?a; Luis Miguel Guti?rrez-Robledo;
Название: Aging Research - Methodological Issues
ISBN: 3030070255 ISBN-13(EAN): 9783030070250
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This is the second edition of a well received book that reviews classical epidemiological and clinical research designs, with a specific focus on aging. Chapters cover basic topics like the scientific method, ethics, and the consequences of certain exclusion criteria. The work also includes a look at clinical concepts like multimorbidity, frailty and functionality. New material includes chapters such as geroscience, health systems research, big data and data mining, financing and future of aging research. The authors reveal the issues and challenges for researchers of age and aging, and also consider, from basic to clinical, and from clinical to public policies of social and health care.The focus on aging is what gives this book its valuable perspective on research methodology. All authors have considerable experience in aging, geriatrics or gerontology, and each chapter includes both a theoretical framework and practical examples of studies in aging. Readers will discover study designs that are reviewed for basic structure, main flaws and advantages, and are analyzed for specific conditions and variables regarding aging.This text is suited to both health care professionals caring for older adults, and researchers who are new to research in aging. It is relevant across the disciplines, including medicine, psychology, social sciences and dentistry, and it supports learning with graphs and figures.

Finger Millet Genome

Автор: Daniels, Kevin Tregaskis, Olga Nayani, Rachel Watson, David
Название: Finger Millet Genome
ISBN: 3031008677 ISBN-13(EAN): 9783031008672
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book is the first comprehensive compilation of deliberations on domestication, genetic and genomic resources, breeding, genetic diversity, molecular maps & mapping of important biotic stress as well as nutritional quality traits, genome sequencing, comparative genomics, functional genomics and genetic transformation.

The Catharanthus Genome

Автор: Kole
Название: The Catharanthus Genome
ISBN: 3030892719 ISBN-13(EAN): 9783030892715
Издательство: Springer
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Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book is the first comprehensive compilation of deliberations on botany, medicinal importance, genetic diversity, classical genetics and breeding, in vitro biosynthesis, somatic embryogenesis, genetic transformation, molecular mapping, genome sequence, and functional genomics of Catharanthus roseus. Catharanthus is the most important medicinal plant in the world that contains about 130 therapeutic alkaloids out of which vinblastine and vincristine are the two highly used anticancer drugs sold by the pharmaceutically industries. Altogether, the book contains about 10 chapters authored by globally reputed experts on the relevant field of this plant. This book is useful to the students, teachers and scientists in the academia and relevant private companies interested in horticulture, genetics, breeding, pathology, entomology, physiology, molecular genetics and breeding, in vitro culture and genetic engineering, and structural and functional genomics. This book is also useful to pharmaceutical industries.


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