Forkhead FOXO Transcription Factors in Development and Disease, Ghaffari, Saghi
Автор: Li Название: The Secret Lives of Transcription Factors ISBN: 3031290275 ISBN-13(EAN): 9783031290275 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This SpringerBrief explores unconventional functions of eight different transcription factors and concludes with a discussion of their biological significance and impact, including effects on processes within the cell nucleaus during development and in adult organisms. Chapter One details unconventional functions of the transcription factors GAGA, HP1, Rb, STAT, ATF-2 and NF-kB. Surprisingly, all of these transcription factors can be found in association with heterochromatin as well as euchromatin, and in some cases unconventional functions have been demonstrated for these heterochromatin-associated factors. Chapter Two focuses on the unconventional functions of STAT and HP1 and discusses their roles in the promotion of longevity, and in protection from cancer and DNA damage. Chapter Three explores the biological significance of the findings presented in the first two chapters and considers how global changes in the epigenome brought about by factors such as STAT and HP1 might affect processes within the cell nucleus during development and in adult organisms. This succinct yet thorough SpringerBrief is essential for researchers studying epigenetics, and to instructors of the subject. It should also appeal to people interested in the control of gene transcription and other processes in the cell nucleus, and to those interested in development.
Автор: Romas, John A. (Professor, Department of Health Science, Minnesota State University-Mankato, USA) Sharma, Manoj (Professor and Program Coordinator, So Название: Transcription and Translation in Health and Disease ISBN: 0323995217 ISBN-13(EAN): 9780323995214 Издательство: Elsevier Science Рейтинг: Цена: 21391.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: My psychologist, Dr. J. Mark Pratt, says "What you do most is what you do best." Certainly, full-time paid employment takes up most of my time, and I am so grateful for that. Coming in close second, however, is mental health treatment. Appointments with psychiatrists/psychologists, mental health support groups, obtaining required blood work from the lab, filling pharmacy prescriptions, going to church, reading literature, and praying/meditating. Also common is doing volunteer work, helping friends and family with tasks, and listening to them when they are troubled. These activities give me positive thoughts that I am contributing to society and help keep me away from the negativity that has been a hallmark of my mental illness. Thus it has become a life that I truly believe is one worth living. In the early stages of recovery (the late 1990s) I did not share this view. But I survived those tumultuous days and have now entered into an expansive place where peace, even joy, is a common experience. The psychiatric and psychological treatments that have made this possible cost my mom, Gwen, a lot of money. Although, I have been able to remove this burden from her more recently. It occurred to me that if I could write a book delineating the various aspects of my treatment program, I could share these helpful concepts with others, virtually for free. That is the spirit in which this book is published, and I hope you can utilize it for increased mental health and well-being!
Автор: Higgins Paul J. Название: Transcription Factors: Methods and Protocols ISBN: 1493957155 ISBN-13(EAN): 9781493957156 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Here, leading researchers describe the latest techniques for investigating the mechanisms underlying transcription factor nuclear-cytoplasmic trafficking, as well as the functional impact of post-translational modifications on transcription factor function.
Автор: Ganji Purnachandra Nagaraju; Pallaval Veera Bramha Название: Role of Transcription Factors in Gastrointestinal Malignancies ISBN: 9811338930 ISBN-13(EAN): 9789811338939 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Нет в наличии.
Описание: This book illustrates the importance of transcription factors in gastrointestinal cancer progression and metastasis with regard to understanding the mechanism and target definition in drug discovery.
Автор: Frank J. III Rauscher; Peter K. Vogt Название: Chromosomal Translocations and Oncogenic Transcription Factors ISBN: 3642644244 ISBN-13(EAN): 9783642644245 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Regulation of gene expression at the level of transcription is one of the major determinants of proper cellular proliferation and differentiation. This volume gives insights into how normal programs of gene expression can be subverted by the action of single transcription factors resulting in a specific tumor type.
Описание: Proceedings of the NATO Advances Study Institute on Molecular Mechanisms of Transcellular Signalling: from the Membrane to the Gene, held at the Island of Spetses, Greece, August 15-27, 1994
Автор: Lutz Nover Название: Plant Promoters and Transcription Factors ISBN: 366222304X ISBN-13(EAN): 9783662223048 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The control of plant gene expression at the transcriptional level is the main subject of this volume. Formation of specific DNA-protein complexes - activating or repressing transcription - is the crux of developmental or environmental control of gene expression.
Автор: Sergio Colonna-Romano; Antonella Leone; Bruno Mare Название: Differential-Display Reverse Transcription-PCR (DDRT-PCR) ISBN: 3540632972 ISBN-13(EAN): 9783540632979 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Identification of differentially expressed genes is one of the major challenges in molecular biology. This technique has been proven to be highly effective in identifying sequences that are differentially expressed in various cell types.
Автор: Takashi Ohyama Название: DNA Conformation and Transcription ISBN: 1489995072 ISBN-13(EAN): 9781489995070 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Despite remarkable progress in genome science, we are still far from a clear understanding of how genomic DNA is packaged without entanglement into a nucleus, how genes are wrapped up in chromatin, how chromatin structure is faithfully inherited from mother to daughter cells, and how the differential expression of genes is enabled in a given cell type. Exploring and answering these questions constitutes one of the next frontiers in the 21st century.
We are just beginning to appreciate how Multifarious DNA structures provide additional structural and functional dimensions to chromatin organization and gene expression. DNA Conformation and Transcription is the first book that compiles the fruits of the studies that have been performed to date to solve the riddle 'written' in DNA conformation ("conformation code"). This book provides a comprehensive overview of the field by covering history of the field, up-to-date topics, clarifications of present day research, and future perspective of what is still to be discovered. Thus, it serves as an invaluable source of information on the "conformation code."
Автор: Brown, William M. Название: Transcription ISBN: 0415271991 ISBN-13(EAN): 9780415271998 Издательство: Taylor&Francis Рейтинг: Цена: 18374.00 р. Наличие на складе: Нет в наличии.
Автор: Robert J. White Название: RNA Polymerase III Transcription ISBN: 3662035200 ISBN-13(EAN): 9783662035207 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This monograph reviews and summarizes the substantial body of work that has been published on the transcription by polymerase III over the past 5 years.
Автор: F. Sierra Название: A Laboratory Guide to In Vitro Transcription ISBN: 3764323574 ISBN-13(EAN): 9783764323578 Издательство: Springer Рейтинг: Цена: 11179.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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