Автор: Rozlosnik N. Название: Nanomedicine in Diagnostics ISBN: 1578087384 ISBN-13(EAN): 9781578087389 Издательство: Taylor&Francis Рейтинг: Цена: 15541.00 р. 22202.00-30% Наличие на складе: Есть (1 шт.) Описание: Research on new sensing concepts has opened the door to a wide variety of microsystems for clinical applications. Such devices are extremely useful for delivering diagnostic information in a fast, simple, and low cost fashion. This book is one of the first to focus on the use of nanotechnology in diagnostics. Designed as a broad survey of the field, this book combines contributions by international experts from divergent fields of study ranging from single molecule diagnostics to cell based systems.
Автор: Val?rie Taly; Jean-Louis Viovy; St?phanie Descroix Название: Microchip Diagnostics ISBN: 1493967320 ISBN-13(EAN): 9781493967322 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Microfluidics-enabled Diagnostic Systems: Markets, Challenges, and Examples.- Capillary-Driven Microfluidic Chips for Miniaturized Immunoassays: Efficient Fabrication and Sealing of Chips Using a "Chip-olate" Process.- Capillary-driven Microfluidic Chips for Miniaturized Immunoassays: Patterning Capture Antibodies using Microcontact Printing and Dry-film Resists.- Fabrication and Evaluation of Microfluidic Immunoassay Devices with Antibody-immobilized Microbeads Retained in Porous Hydrogel Micropillars.- Using Electrophoretic Immunoassay to Monitor Hormone Secretion.- On-chip Magnetic Particle-based Immunoassays using Multilaminar Flow for Clinical Diagnostic.- Digital Microfluidics Assisted Sealing of Individual Magnetic Particles in fFmtoliter-sized Reaction wells for Single-molecule Detection.- Microfluidic DNA Stretching Device for Single-Molecule Diagnostics.- Droplet Microfluidic and Magnetic Particles Platform for Cancer Typing.- SlipChip Device for Digital Nucleic Acid Amplification.- Multiplex Detection of KRAS Mutations using Passive Droplet Fusion.- Droplet-based Microfluidics Digital PCR for the Detection of KRAS Mutations.- Negative Enrichment of Circulating Tumor Cells in Blood Using a Microfluidic Chip.- Microfluidic Based Bacteria Isolation from Whole Blood for Diagnostics of Blood Stream Infection.- Microfluidic POlatform for Parallel Single Cell Analysis for Diagnostic Applications.- FISH-in-CHIPS.
Автор: Coppola Название: Molecular Pathology and Diagnostics of Cancer ISBN: 9400771916 ISBN-13(EAN): 9789400771918 Издательство: Springer Рейтинг: Цена: 30039.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses.
Автор: Jose Luis Garcia-Gimenez Название: Epigenetic Biomarkers and Diagnostics ISBN: 0128018992 ISBN-13(EAN): 9780128018996 Издательство: Elsevier Science Рейтинг: Цена: 16338.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
"Epigenetic Biomarkers and Diagnostics" comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based technologies to discover and analyze epigenetic biomarkers. The book concludes with an account of DNA methylation, post-translational modifications and noncoding RNAs as the most promising biomarkers for cancer (i.e. breast, lung, colon, etc.), metabolic disorders (i.e. diabetes and obesity), autoimmune diseases, infertility, allergy, infectious diseases, and neurological disorders.
The book describes the challenging aspects of research in epigenetics, and current findings regarding new epigenetic elements and modifiers, providing guidance for researchers interested in the most advanced technologies and tested biomarkers to be used in the clinical diagnosis or prognosis of disease. Focuses on recent progress in several areas of epigenetics, general concepts regarding epigenetics, and the future prospects of this discipline in clinical diagnostics and prognosticsDescribes the importance of the quality of samples and clinical associated data, and also the ethical issues for epigenetic diagnosticsDiscusses the advances in epigenomics technologies, including next-generation sequencing based tools and applicationsExpounds on the utility of epigenetic biomarkers for diagnosis and prognosis of several diseases, highlighting the study of these biomarkers in cancer, cardiovascular and metabolic diseases, infertility, and infectious diseasesIncludes a special section that discusses the relevance of biobanks in the maintenance of high quality biosamples and clinical-associated data, and the relevance of the ethical aspects in epigenetic studies
Автор: Thurin Название: Molecular Diagnostics for Melanoma ISBN: 1627037268 ISBN-13(EAN): 9781627037266 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides both clinicians and scientists with technical information and extensive background information on the wide ranging approaches available in the diagnostics of melanoma. It features step-by-step, readily reproducible laboratory protocols.
Автор: Patrinos, George Название: Molecular Diagnostics ISBN: 0128029714 ISBN-13(EAN): 9780128029718 Издательство: Elsevier Science Рейтинг: Цена: 18528.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter.
Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the battery of the most widely used molecular pathology techniques. New chapters have been added, including the various new technologies involved in next-generation sequencing (mutation detection, gene expression, etc.), mass spectrometry, and protein-specific methodologies.
All revised chapters have been completely updated, to include not only technology innovations, but also novel diagnostic applications. As with previous editions, each of the chapters in this section includes a brief description of the technique followed by examples from the area of expertise from the selected contributor.
The second part of the book attempts to integrate previously analyzed technologies into the different aspects of molecular diagnostics, such as identification of genetically modified organisms, stem cells, pharmacogenomics, modern forensic science, molecular microbiology, and genetic diagnosis. Part three focuses on various everyday issues in a diagnostic laboratory, from genetic counseling and related ethical and psychological issues, to safety and quality management.
Описание: Principles of Molecular Diagnostics and Personalized Cancer Medicine" The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today’s subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention—all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge resource, readers will explore broad, comprehensive perspectives on the current trends in molecular diagnosis of cancer and personalized cancer medicine. Authoritative discussions share insights from noted experts in cancer research, clinical trials, molecular diagnostics, personalized therapy, bioinformatics, and federal regulations. From the basic mechanisms of carcinogenesis to the most advanced molecular screening, staging, and treatment technologies, readers will discover clear and straightforward discussions directly relevant to patient diagnosis and care. Improve your understanding of… • The basic mechanisms of carcinogenesis— including material on cell proliferation, signal transduction pathways, cancer stem cells, and the interaction between genetics and environmental factors. • The most current molecular techniques —including polymerase chain reaction (PCR) technique, single nucleotide polymorphisms, cancer cytogenomics and epigenetics, whole-genome assessments, and next- generation sequencing. • Molecular tests —including molecular screening, minimal residual disease detection, circulating tumor cell tests, molecular tumor staging, and molecular cancer prognosis assessment. • Imaging and screening technologies —including molecular imaging, genetic tests, biostatistics, and bioinformatics. • The molecular basis of therapy —including critical molecules as special treatment targets, particularly genes/DNA, RNA, micro RNAs, proteins/antibodies, and nanoparticles. • Molecular diagnostics – including updated molecular diagnostic approaches to common malignancies and role of pathology in targeted cancer management. • Targeted treatment – including personalized medicine and targeted therapy for commonly occurring malignancies— plus insights on new approaches to targeted drug discovery and the future of molecular oncology!
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