Автор: Jose Luis Garcia-Gimenez Название: Epigenetic Biomarkers and Diagnostics ISBN: 0128018992 ISBN-13(EAN): 9780128018996 Издательство: Elsevier Science Рейтинг: Цена: 16338.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
"Epigenetic Biomarkers and Diagnostics" comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based technologies to discover and analyze epigenetic biomarkers. The book concludes with an account of DNA methylation, post-translational modifications and noncoding RNAs as the most promising biomarkers for cancer (i.e. breast, lung, colon, etc.), metabolic disorders (i.e. diabetes and obesity), autoimmune diseases, infertility, allergy, infectious diseases, and neurological disorders.
The book describes the challenging aspects of research in epigenetics, and current findings regarding new epigenetic elements and modifiers, providing guidance for researchers interested in the most advanced technologies and tested biomarkers to be used in the clinical diagnosis or prognosis of disease. Focuses on recent progress in several areas of epigenetics, general concepts regarding epigenetics, and the future prospects of this discipline in clinical diagnostics and prognosticsDescribes the importance of the quality of samples and clinical associated data, and also the ethical issues for epigenetic diagnosticsDiscusses the advances in epigenomics technologies, including next-generation sequencing based tools and applicationsExpounds on the utility of epigenetic biomarkers for diagnosis and prognosis of several diseases, highlighting the study of these biomarkers in cancer, cardiovascular and metabolic diseases, infertility, and infectious diseasesIncludes a special section that discusses the relevance of biobanks in the maintenance of high quality biosamples and clinical-associated data, and the relevance of the ethical aspects in epigenetic studies
Автор: Nakamura Название: Cancer Diagnostics. 2004 ISBN: 1588291677 ISBN-13(EAN): 9781588291677 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: offers a review of the considerable advances in technology during the past several years; the authors were concerned primarily with clinical laboratory tests; these tests may already, or in the near future, help in the early detection, evaluation, and prediction of human tumors for specific therapeutic decisions.
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