Описание: The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. www.springeronline.com
Автор: Alexander Vinks; Hartmut Derendorf; Johan Mouton ( Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics ISBN: 0387756124 ISBN-13(EAN): 9780387756127 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.
Автор: Bauer Название: Handbook of clinical pharmacokinetics ISBN: 007142542X ISBN-13(EAN): 9780071425421 Издательство: McGraw-Hill Рейтинг: Цена: 6347.00 р. Наличие на складе: Поставка под заказ.
Описание: Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. It also features calculation methods, algorithms for choosing the best calculation method, and case studies.
Автор: Bauer, Larry A. Название: Applied clinical pharmacokinetics ISBN: 0071476288 ISBN-13(EAN): 9780071476287 Издательство: McGraw-Hill Рейтинг: Цена: 7720.00 р. Наличие на складе: Поставка под заказ.
Описание: Features coverage of drug dosing and monitoring. This book focuses on the standardized techniques and approaches to patient-specific dosing. It also contains sections on dosing strategies in the chapters and a chapter on sirolimus.
Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.
Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.
Автор: Krishna, Rajesh Название: Biopharmaceutics applications in drug development ISBN: 1441944346 ISBN-13(EAN): 9781441944344 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The highly experienced authors here present readers with step-wise, detail-conscious information to develop quality pharmaceuticals. It provides a specific focus on the integration of regulatory considerations and includes case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs.
Автор: Bauer Название: Applied Clinical Pharmacokinetics ISBN: 0071794581 ISBN-13(EAN): 9780071794589 Издательство: McGraw-Hill Рейтинг: Цена: 12697.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Helps you learn the clinical application of pharmacokinetics. This book delivers clear and clinically relevant coverage of drug dosing and drug monitoring that no other text can match. It offers the standardized techniques and approaches to patient-specific dosing, and information on pharmacokinetically monitored drugs.
Описание: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.
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