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Novel Therapeutic Proteins: Selected Case Studies, Klaus Dembowsky


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Цена: 13063р.
Кол-во:
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Автор: Klaus Dembowsky
Название:  Novel Therapeutic Proteins: Selected Case Studies
Издательство: Wiley
Классификация:
Биотехнология

ISBN: 3527302700
ISBN-13(EAN): 9783527302703
ISBN: 3-527-30270-0
ISBN-13(EAN): 978-3-527-30270-3
Обложка/Формат: Hardback
Страницы: 382
Вес: 0.86 кг.
Дата издания: February 14, 2001
Язык: ENG
Издание: Illustrated ed
Иллюстрации: Ill.
Размер: 25.10 x 16.92 x 2.36 cm
Читательская аудитория: Postgraduate, research & scholarly
Подзаголовок: Selected case studies
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Англии
Описание: This book describes medical applications of recombinant proteins and monoclonal antibodies, some of which have already been on the market for several years while others have only recently been launched. It also highlights the manufacturing processes for individual products, the strategies that were taken by companies in the clinical development, and the hurdles that were encountered in clinical trials and had to be overcome before approval by regulatory authorities. Finally, this book illustrates strategies to modify and improve the pharmacodynamic and pharmacokinetic properties of naturally occurring proteins thus paving the way for a new era in biotechnology. Foreword written by Jurgen Drews.
Дополнительное описание: Кол-во стр.: 384
Формат: 245 x 174
Дата издания: 2000
Илюстрации: Illustrations
Вес: 850
Круг читателей: undergraduate; postgraduate; research, professional





Fundamentals of Machine Learning for Predictive Data Analytics: Algorithms, Worked Examples, and Case Studies

Автор: Kelleher John D., Macnamee Brian, D`Arcy Aoife
Название: Fundamentals of Machine Learning for Predictive Data Analytics: Algorithms, Worked Examples, and Case Studies
ISBN: 0262029448 ISBN-13(EAN): 9780262029445
Издательство: Wiley
Рейтинг:
Цена: 6793 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

A comprehensive introduction to the most important machine learning approaches used in predictive data analytics, covering both theoretical concepts and practical applications.

Machine learning is often used to build predictive models by extracting patterns from large datasets. These models are used in predictive data analytics applications including price prediction, risk assessment, predicting customer behavior, and document classification. This introductory textbook offers a detailed and focused treatment of the most important machine learning approaches used in predictive data analytics, covering both theoretical concepts and practical applications. Technical and mathematical material is augmented with explanatory worked examples, and case studies illustrate the application of these models in the broader business context.

After discussing the trajectory from data to insight to decision, the book describes four approaches to machine learning: information-based learning, similarity-based learning, probability-based learning, and error-based learning. Each of these approaches is introduced by a nontechnical explanation of the underlying concept, followed by mathematical models and algorithms illustrated by detailed worked examples. Finally, the book considers techniques for evaluating prediction models and offers two case studies that describe specific data analytics projects through each phase of development, from formulating the business problem to implementation of the analytics solution. The book, informed by the authors' many years of teaching machine learning, and working on predictive data analytics projects, is suitable for use by undergraduates in computer science, engineering, mathematics, or statistics; by graduate students in disciplines with applications for predictive data analytics; and as a reference for professionals.

Advances in Protein Chemistry and structural biology

Автор: Donev, Rossen
Название: Advances in Protein Chemistry and structural biology
ISBN: 0128123907 ISBN-13(EAN): 9780128123904
Издательство: Elsevier Science
Рейтинг:
Цена: 10266 р. 11407.00 -10%
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Chromatin Proteins and Transcription Factors as Therapeutic Targets, the latest volume in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

Therapeutic Peptides Proteins Formu

Автор: Banga
Название: Therapeutic Peptides Proteins Formu
ISBN: 146656606X ISBN-13(EAN): 9781466566064
Издательство: Taylor&Francis
Рейтинг:
Цена: 15153 р.
Наличие на складе: Поставка под заказ.

Описание: There are more than 500 biopharmaceuticals on the market, including more than 200 therapeutic proteins, making biologics the fastest growing sector in the biopharmaceutical market. These products include more than 40 monoclonal antibodies, for indications ranging from treatment or mitigation of various types of cancer to rheumatoid arthritis. The clinical application of these therapeutic peptides and proteins is limited by several problems, such as lack of physical and chemical stability or the lack of desirable attributes for adequate absorption or distribution. Thus, as these therapeutic peptides and proteins are made available, it will be essential to formulate these drugs into safe, stable, and efficacious delivery systems. The pharmaceutical scientist involved in this effort needs to call upon the knowledge of several disciplines, such as pharmaceutics, medicinal chemistry, biochemistry, microbiology, and chemical engineering and needs to keep abreast with the latest research in the published literature. Therapeutic Peptides and Proteins: Formulation, Processing, and Delivery Systems, Third Edition provides a comprehensive overview of the field for scientists in industry and academia and for students, while also providing practical information on the challenges facing the formulation and delivery aspects of these unique macromolecules. In particular, the book: Explains how recombinant DNA techniques now allow us to produce therapeutic proteins in a commercially viable form Discusses the physical and chemical pathways of peptide and protein degradation Includes a detailed discussion of protein formulation and lyophilization Overviews the pharmacokinetic aspects of therapeutic peptides and proteins and discusses controlled delivery systems for parenteral administration, including microsphere formulations Discusses research progress on oral, transdermal, mucosal, and topical delivery systems discusses transdermal and topical delivery

Автор: A. Mountain
Название: Biotechnology: A Multi-Volume Comprehensive Treatise, Volume 5a&b, Recombinant Proteins, Monoclonal Antibodies, Therapeutic Genes, Genomics and Bioinformatics, 2nd, Completely Revised Edition
ISBN: 3527304320 ISBN-13(EAN): 9783527304325
Издательство: Wiley
Цена: 36575 р.
Наличие на складе: Нет в наличии.

Therapeutic Peptides and Proteins

Автор: Ajay K. Banga
Название: Therapeutic Peptides and Proteins
ISBN: 0849316308 ISBN-13(EAN): 9780849316302
Издательство: Taylor&Francis
Цена: 10346 р.
Наличие на складе: Поставка под заказ.

Inhalation Delivery Of Therapeutic Peptides And Proteins

Автор: Adjei Akwete
Название: Inhalation Delivery Of Therapeutic Peptides And Proteins
ISBN: 0824797809 ISBN-13(EAN): 9780824797805
Издательство: Informa
Цена: 15612 р.
Наличие на складе: Нет в наличии.

Описание: This exhaustive reference-the first book of its kind to describe in detail the functionality of the human respiratory tract and its impact on both local and systemic delivery of biotherapeutic and macromolecular drug systems-offers comprehensive analyses of peptide and protein drug delivery through the lung.
Summarizes over 130 patents granted worldwide on alternative systems for pulmonary delivery of therapeutic drugs-especially peptides and proteins!
Examining macromolecular drug delivery as an efficient, patient-friendly, and cost-effective method of treatment, Inhalation Delivery of Therapeutic Peptides and Proteins discusses

  • airway physiology and biomechanics
  • the pharmaceutical concerns associated with the respiratory tract as a viable port of drug entry to the body
  • key peptide drugs under development and in use to treat local lung disease, including cyclosporines, interferons, antitrypsins, protease inhibitors, and deoxyribonucleases
  • the systemic delivery of peptide and protein drugs using fine-particle technology
  • gene therapy employing gene delivery through the airways
  • new developments in pulmonary delivery technologies emphasizing inhaled peptide and protein drugs
  • guidelines for the successful introduction of peptide inhalation aerosol products into the marketplace
  • and much more!
  • Aggregation of Therapeutic Proteins

    Автор: Wang
    Название: Aggregation of Therapeutic Proteins
    ISBN: 0470411961 ISBN-13(EAN): 9780470411964
    Издательство: Wiley
    Рейтинг:
    Цена: 12645 р.
    Наличие на складе: Нет в наличии.

    Описание: While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Aggregation of Therapeutic Proteins provides an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process.

    Novel Therapeutic Agents for the Treatment of Autoimmune Diseases

    Автор: Strand
    Название: Novel Therapeutic Agents for the Treatment of Autoimmune Diseases
    ISBN: 0824797485 ISBN-13(EAN): 9780824797485
    Издательство: Taylor&Francis
    Рейтинг:
    Цена: р.
    Наличие на складе: Невозможна поставка.

    Описание: Provides a detailed survey of therapies for autoimmune diseases, exploring the rationale for their use and clinical data regarding their potential benefit.

    Case Studies in Novel Food Processing Technologies,

    Автор: C J Doona
    Название: Case Studies in Novel Food Processing Technologies,
    ISBN: 1845695518 ISBN-13(EAN): 9781845695514
    Издательство: Elsevier Science
    Цена: 19355 р. 21505.00 -10%
    Наличие на складе: Поставка под заказ.

    Описание: Novel food processing technologies have significant potential to improve product quality and process efficiency. Commercialisation of new products and processes brings exciting opportunities and interesting challenges. Case studies in novel food processing technologies provides insightful, first-hand experiences of many pioneering experts involved in the development and commercialisation of foods produced by novel processing technologies.
    Part one presents case studies of commercial products preserved with the leading nonthermal technologies of high pressure processing and pulsed electric field processing. Part two broadens the case histories to include alternative novel techniques, such as dense phase carbon dioxide, ozone, ultrasonics, cool plasma, and infrared technologies, which are applied in food preservation sectors ranging from fresh produce, to juices, to disinfestation. Part three covers novel food preservation techniques using natural antimicrobials, novel food packaging technologies, and oxygen depleted storage techniques. Part four contains case studies of innovations in retort technology, microwave heating, and predictive modelling that compare thermal versus non-thermal processes, and evaluate an accelerated 3-year challenge test.
    With its team of distinguished editors and international contributors, Case studies in novel food processing technologies is an essential reference for professionals in industry, academia, and government involved in all aspects of research, development and commercialisation of novel food processing technologies.

    • Provides insightful, first-hand experiences of many pioneering experts involved in the development and commercialisation of foods produced by novel processing technologies
    • Presents case studies of commercial products preserved with the leading nonthermal technologies of high pressure processing and pulsed electric field processing
    • Features alternative novel techniques, such as dense phase carbon dioxide, ozone, ultrasonics, cool plasma, and infrared technologies utilised in food preservation sectors
    Case Studies in Novel Food Processing Technologies: Innovations in Processing, Packaging, and Predictive Modelling

    Автор: Doona Christopher, Kustin Kenneth, Feeherry Florence
    Название: Case Studies in Novel Food Processing Technologies: Innovations in Processing, Packaging, and Predictive Modelling
    ISBN: 0081014821 ISBN-13(EAN): 9780081014820
    Издательство: Elsevier Science
    Цена: 19355 р. 21505.00 -10%
    Наличие на складе: Есть у поставщика Поставка под заказ.

    Описание: Novel food processing technologies have significant potential to improve product quality and process efficiency. Commercialisation of new products and processes brings exciting opportunities and interesting challenges. Case studies in novel food processing technologies provides insightful, first-hand experiences of many pioneering experts involved in the development and commercialisation of foods produced by novel processing technologies.Part one presents case studies of commercial products preserved with the leading nonthermal technologies of high pressure processing and pulsed electric field processing. Part two broadens the case histories to include alternative novel techniques, such as dense phase carbon dioxide, ozone, ultrasonics, cool plasma, and infrared technologies, which are applied in food preservation sectors ranging from fresh produce, to juices, to disinfestation. Part three covers novel food preservation techniques using natural antimicrobials, novel food packaging technologies, and oxygen depleted storage techniques. Part four contains case studies of innovations in retort technology, microwave heating, and predictive modelling that compare thermal versus non-thermal processes, and evaluate an accelerated 3-year challenge test.With its team of distinguished editors and international contributors, Case studies in novel food processing technologies is an essential reference for professionals in industry, academia, and government involved in all aspects of research, development and commercialisation of novel food processing technologies.

    Novel Therapeutic Approaches to the Treatment of Parkinson`s Disease

    Автор: Hopkins
    Название: Novel Therapeutic Approaches to the Treatment of Parkinson`s Disease
    ISBN: 3319399241 ISBN-13(EAN): 9783319399249
    Издательство: Springer
    Рейтинг:
    Цена: 21845 р.
    Наличие на складе: Есть у поставщика Поставка под заказ.

    Описание: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

    Practical Handbook of Echocardiography: 101 Case Studies

    Автор: Jing Ping Sun
    Название: Practical Handbook of Echocardiography: 101 Case Studies
    ISBN: 1405195568 ISBN-13(EAN): 9781405195560
    Издательство: Wiley
    Рейтинг:
    Цена: 10868 р.
    Наличие на складе: Есть у поставщика Поставка под заказ.

    Описание: Practical Handbook of Echocardiography: 101 Case Studies Echocardiography is now one of the most commonly used diagnostic imaging tools, yet many clinicians remain unaware of the range of conditions echo can reveal or how echo can be used to help plan th


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