Описание: Recombinant DNA techniques have revolutionized the isolation and production of antibodies. This work details protocols which allow the researcher to isolate a new antibody, analyse its properties, format the right antibody molecule or fragment, and produce it in usable quantities.
Автор: Crowe James Название: Antibodies for Infectious Diseases ISBN: 1555817351 ISBN-13(EAN): 9781555817350 Издательство: Taylor&Francis Рейтинг: Цена: 15675 р. Наличие на складе: Поставка под заказ.
Описание: Provides a broad survey across important aspects for understanding mechanisms of immunity to infectious disease, including general features of antibodies and approaches to antibody discovery, individual chapters highlighting antibodies against particular pathogens, and state-of-the-art technical advances and expression systems. This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Автор: James W. Goding Название: Monoclonal Antibodies, ISBN: 0122870239 ISBN-13(EAN): 9780122870231 Издательство: Elsevier Science Рейтинг: Цена: 10505 р. Наличие на складе: Поставка под заказ.
Описание: Monoclonal Antibodies have applications in different areas of biology and medicine. This edition provides an integrated treatment of both the production and application of monoclonal antibodies. It also gives detailed and critical accounts of the theory, production, purification, fragmentation, storage and radiolabelling of monoclonal antibodies.
Название: Monoclonal Antibodies ISBN: 0199637237 ISBN-13(EAN): 9780199637232 Издательство: Oxford Academ Цена: 15065 р. Наличие на складе: Поставка под заказ.
Описание: This text covers the preparation, testing, derivation and application of monoclonal antibodies. Modern immunological techniques incorporating tried and tested methodologies are described, as well as the standard somatic hybridization and recombinant techniques, including the use of phage libraries.
Автор: Federico Maurizio Название: Lentivirus Gene Engineering Protocols ISBN: 1607615320 ISBN-13(EAN): 9781607615323 Издательство: Springer Рейтинг: Цена: 13859 р. Наличие на складе: Поставка под заказ.
Описание: Authoritative and timely, Lentivirus Gene Engineering Protocols, Second Edition, covers the most relevant issues and techniques of LV-based gene engineering. This practical guide is aimed at those who wish to know more about this vital area of study.
Описание: Genetic Engineering, Volume 25 contains discussions of contemporary and relevant topics in genetics, including: - Genotyping by Mass Spectrometry;- Development of Targeted Viral Vectors for Cardiovascular Gene Therapy; - Practical Applications of Rolling Circle Amplification of DNA Templates; - Bacterial ION Channels; - Applications of Plant Antiviral Proteins;- The Bacterial Scaffoldin: Structure, Function and Potential Applications in the Nanosciences. This principles and methods approach to genetics and genetic engineering is essential reading for all academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in this continuously emerging field.
Описание: This volume presents state-of-the-art discussions in Genetics and Genetic engineering by focusing on plant science and technology, transport protein biochemistry, cell biology and gene therapy research.
Описание: Genetic Engineering, Volume 24 contains discussions of contemporary and relevant topics in genetics, including: -Gene silencing: principles and applications, -Integrins and the myocardium, -Plant virus gene vectors: biotechnology and applications in agriculture and medicine, -Novel approaches to controlling transcription, -Use of DNA polymorphisms in genetic mapping, -Application of FLP/FRT site-specific DNA recombination system in plants.This principles and methods approach to genetics and genetic engineering is essential reading for all academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in this continuously emerging field.
Описание: Introduction to Alzheimer's Disease, David Allsop. The Genetics of Alzheimer's Disease, Nick Brindle and Peter St. George-Hyslop. Advances in Methodology and Current Prospects for Primary Drug Therapies for Alzheimer's Disease, David S. Knopman. Production and Functional Assays of Recombinant Secreted Amyloid Precursor Protein (APP) (sAPPa), Steven W. Barger. Quantifying Ab1-40 and Ab1-42 Using Sandwich-ELISA, Daniel M. Skovronsky, Jun Wang, Virginia M.-Y. Lee, and Robert W. Doms. Electrophoretic Separation and Immunoblotting of Ab1-40 and Ab1-42 Matthias Staufenbiel and Paolo A. Paganetti. Ab-Induced Proinflammatory Cytokine Release from Differentiated Human THP-1 Monocytes, Kurt R. Brunden, June Kocsis-Angle, Paula Embury, and Stephen L. Yates. Effects of the b-Amyloid Peptide on Membrane Ion Permeability, Hugh A. Pearson. Analysis of b-Amyloid Peptide Degradation In Vitro, Barbara Cordell and Asha Naidu. Posttranslational Modifications of the Amyloid Precursor Protein: Ectodomain Phosphorylation and Sulfation, Jochen Walter and Christian Haass. Posttranslational Modifications of the Amyloid Precursor Protein: Glycosylation, Chen Liu, Tomasz Rozmyslowicz, Magda Stwora-Wojczyk, Boguslaw Wojczyk, and Steven L. Spitalnik. Using an Amyloid Precursor Protein (APP) Reporter to Characterize a-Secretase, Susan Boseman Roberts. Inhibition of a-Secretase by Zinc Metalloproteinase Inhibitors, S. Parvathy, Anthony J. Turner, and Nigel M. Hooper. Development of Neoepitope Antibodies Against the b-Secretase Cleavage Site in the Amyloid Precursor Protein Carol W. Gray and Eric H. Karran. b-Secretase: Tissue Culture Studies of Sequence Specificity, Inhibitors, and Candidate Enzymes, Martin Citron. Using g-Secretase Inhibitors to Distiguish the Generation of the Ab Peptides Terminating at Val-40 and Ala-42, Paolo A. Paganetti and Matthia Staufenbiel. Designing Animal Models of Alzheimer's Disease with Amyloid Precursor Protein (APP) Transgenes, Jeanne F. Loring. Phosphorylation of Amyloid Precursor Protein (APP) Family Proteins, Toshiharu Suzuki, Kanae Ando, Ko-ichi Iijima, Shinobu Oguchi, and Shizu Takeda. Determining the Transmembrane Topology of the Presenilins, Gopal Thinakaran and Andrew Doan. Normal Proteolytic Processing of the Presenilins, Henrike Hartmann and Bruce A. Yankner. Apoptotic Proteolytic Cleavage of the Presenilins by Caspases, Tae-Wan Kim. The Phosphorylation of Presenilin Proteins, Jochen Walter. Interaction of the Presenilins with the Amyloid Precursor Protein (APP), Andreas Weidemann, Krzysztof Paliga, Ulrike DГјrrwang, Friedrich Reinhard, Dai Zhang, Rupert Sandbrink, GeneviГЁve Evin, Colin L. Masters, and Konrad Beyreuther. Distribution of Presenilins and Amyloid Precursor Protein (APP) in Detergent-Insoluble Membrane Domains, Edward T. Parkin, Anthony J. Turner and Nigel M. Hooper. Characterization and Use of Monoclonal Antibodies to Tau and Paired Helical Filament Tau, Peter Davies. Tau Phosphorylation Both In Vitro and in Cells. C. Hugh Reynolds, Graham M. Gibb, and Simon Lovestone. Transglutaminase-Catalyzed Formation of Alzheimer-Like Insoluble Complexes from Recombinant Tau, Brian J. Balin and Denah M. Appelt. Index.
Автор: Robert Aitken (Ed.) Название: Antibody Phage Display ISBN: 1603273018 ISBN-13(EAN): 9781603273015 Издательство: Springer Рейтинг: Цена: 18479 р. Наличие на складе: Поставка под заказ.
Описание: Phage display technology has revolutionized approaches to the analysis of biomedical problems, impacting the fields of immunology, cell biology, biotechnology, pharmacology, and drug discovery. This title provides a resource that guides readers in the design and execution of experiments based around antibody phage display.
Описание: Describes an integrated protein biochip system including protein localization, biocomputing and signaling pathways. This book discusses a fresh micro array tube with incorporation of nuclear and cytoplasmic protein purification and biocomputing technologies, intended for setting-up signaling pathways and making new discoveries.