Medicinal Chemistry of Anticancer Drugs,, Carmen Avendano

Автор: Carmen Avendano
Название: Medicinal Chemistry of Anticancer Drugs
ISBN: 0444626492 ISBN-13(EAN): 9780444626493
Издательство: Elsevier Science
Цена: 23244.00 р.
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Описание: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. . Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. . Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design.

Автор: Carmen Avendano
Название: Medicinal Chemistry of Anticancer Drugs
ISBN: 0444626492 ISBN-13(EAN): 9780444626493
Издательство: Elsevier Science
Рейтинг:
Цена: 23244.00 р.
Наличие на складе: Поставка под заказ.

Описание: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. . Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. . Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design.

Автор: Bathaie S.
Название: Mechanism of the Anticancer Effect of Phytochemicals
ISBN: 0128038764 ISBN-13(EAN): 9780128038765
Издательство: Elsevier Science
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Цена: 18528.00 р.
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Описание: Volume 37 will provide details on the major chemical constituents of medicinal plants and their mechanism of action as the anticancer compounds. This special issue, in addition to the previous volume (volume 36 of The Enzyme series was on Natural Products and Cancer Signaling Targets: Isoprenoids, Polyphenols and Flavonoids), will highlight the significant advance made in the field in elucidating mechanisms of anticancer effect of the major phytochemicals.

Автор: Jaouen
Название: Medicinal Organometallic Chemistry
ISBN: 3642131840 ISBN-13(EAN): 9783642131844
Издательство: Springer
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Цена: 49631.00 р.
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Описание: Contents: Gerard Jaouen, Nils Metzler-Nolte : Introduction ; Stephane GIBAUD and Gerard JAOUEN: Arsenic - based drugs: from Fowler`s solution to modern anticancer chemotherapy; Megan Hogan and Matthias Tacke : Titanocenes - Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer;

Автор: Muriel, Le Roux
Название: Anticancer Drugs: Navelbine(R) and Taxotere(R)
ISBN: 1785481452 ISBN-13(EAN): 9781785481451
Издательство: Elsevier Science
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Цена: 16001.00 р.
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Описание: Among the many forms of cancer treatment, chemotherapy remains an important part of the arsenal in which Navelbine and Taxotere play a major role.These medicines result from molecules discovered by French researchers of the Institut de Chimie des Substances Naturelles (ICSN) of the CNRS, directed by Pierre Potier. By recounting this history, the authors of this book attempt to illustrate how the work of themselves and others, united in a community, has helped obtain these results. After having explained the strategy of the French policy makers to promote the French chemistry of natural substances, the authors explore how the academic efforts in this field have evolved, and the alignment between science and its applications has become increasingly present. The contributions of the CNRS to the industry, and vice versa, offer an alternative image of public research relationships and industrial research, where CNRS researchers are able to extend the limits of freedom and creativity. It is to account for this complexity that the authors here have chosen to write this history together, which is in a sense exemplary.Due to an association between history and chemistry, this book explains these discoveries by placing them in their specific politic, economic and scientific contexts.

Автор: Teicher
Название: Anticancer Drug Development Guide. 2ed.2004
ISBN: 1588292282 ISBN-13(EAN): 9781588292285
Издательство: Springer
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Цена: 34799.00 р.
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Описание: This thoroughly updated and expanded second edition of Beverly Teicher's widely used classic survey provides a step-by-step guide to anticancer drug development from initial design through FDA approval. The authors have included new material on the use of high throughput screening in industry, on specialized in vitro/in vivo procedures employed by the National Cancer Institute (NCI) in preclinical drug evaluations, and on nonclinical testing to support both human clinical trials, as well as trials of biologic oncology products. The chapters on phase I, II, and III clinical trials and on novel phase II clinical trial designs for targeted therapies have been significantly updated, along with those on cancer drug development in Europe, working with the NCI, and the FDA's role in cancer drug development and setting requirements for approval.

Автор: Missailidis
Название: Anticancer Therapeutics
ISBN: 0470723033 ISBN-13(EAN): 9780470723036
Издательство: Wiley
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Цена: 24386.00 р.
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Описание: Written by the winner of the 2008 Mike Price Fellowship The need to re-address known anti-cancer agents and discover new ones are of paramount importance. Anticancer Therapeutics provides a comprehensive overview of the wealth of information currently available on this important and fast-moving subject.

Автор: L. Harivardhan Reddy; Patrick Couvreur
Название: Macromolecular Anticancer Therapeutics
ISBN: 1441905065 ISBN-13(EAN): 9781441905062
Издательство: Springer
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Цена: 36570.00 р.
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Описание: Cancer treatment using Macromolecular therapeutics has considerably improved the survival benefit for the patients. This book assembles various types and aspects of macromolecular anticancer therapeutics for cancer therapy and conveys the importance of this interdisciplinary field.

Автор: Patric
Название: An Introduction to Medicinal Chemistry.2ed IE
ISBN: 0198505337 ISBN-13(EAN): 9780198505334
Издательство: Oxford Academ
Цена: 2693.00 р.
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Описание: This lively, highly illustrated text provides undergraduate and postgraduate students with an accessible introduction to medicinal chemistry. It covers basic principles and background, and then describes the general tactics and strategies involved in developing an effective drug. Through the use of numerous examples it highlights both the difficulties faced by the medicinal chemist and the great potential of rational drug design. The second edition has five new chapters and is updated to include recent advances in the field. Updated throughout with the latest descoveries Five new chapters covering the molecular structure of receptors and the mechanisms of signal transduction combinatorial synthesis the role of computers in drug design adrenergics drug discovery and drug development