Описание: Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to design clinical trials according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.
Описание: Providing practical information and tools that engineers can use to maximize the profitability and reliability of their fluid catalytic cracking (FCC) operations, this book focuses on the developments, the shift to using FCC to process lower quality crudes, and on troubleshooting.
Описание: Advances in Industrial Mixing is a companion volume and update to the Handbook of Industrial Mixing. The second volume fills in gaps for a number of industries that were not covered in the first edition. Significant changes in five of the fundamental areas are covered in entirely updated or new chapters.
Автор: Green, Donald W. Perry, Robert H. Название: Perry`s chemical engineers` handbook ISBN: 0071422943 ISBN-13(EAN): 9780071422949 Издательство: McGraw-Hill Рейтинг: Цена: 26596.00 р. Наличие на складе: Поставка под заказ.
Описание: Covers various aspects of chemical engineering - from the fundamentals to details on computer applications and control. This title features 2,400 pages and 700 illustrations.
Автор: Matsui Shigeyuki Название: Design and Analysis of Clinical Trials for Predictive Medicine ISBN: 1466558156 ISBN-13(EAN): 9781466558151 Издательство: Taylor&Francis Рейтинг: Цена: 17609.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Design and Analysis of Clinical Trials for Predictive Medicine provides statistical guidance on conducting clinical trials for predictive medicine. It covers statistical topics relevant to the main clinical research phases for developing molecular diagnostics and therapeutics--from identifying molecular biomarkers using DNA microarrays to confirming their clinical utility in randomized clinical trials.
The foundation of modern clinical trials was laid many years before modern developments in biotechnology and genomics. Drug development in many diseases is now shifting to molecularly targeted treatment. Confronted with such a major break in the evolution toward personalized or predictive medicine, the methodologies for design and analysis of clinical trials is now evolving.
This book is one of the first attempts to contribute to this evolution by laying a foundation for the use of appropriate statistical designs and methods in future clinical trials for predictive medicine. It is a useful resource for clinical biostatisticians, researchers focusing on predictive medicine, clinical investigators, translational scientists, and graduate biostatistics students.
Автор: Donald M. Mattox Название: Handbook of Physical Vapor Deposition (PVD) Processing, ISBN: 0815520379 ISBN-13(EAN): 9780815520375 Издательство: Elsevier Science Рейтинг: Цена: 38908.00 р. Наличие на складе: Поставка под заказ.
Описание: Explains various aspects of physical vapor deposition (PVD) process technology from the characterizing and preparing the substrate material, through deposition processing and film characterization, to post-deposition processing.
Автор: Rointan F. Bunshah Название: Handbook of Hard Coatings, ISBN: 0815514387 ISBN-13(EAN): 9780815514381 Издательство: Elsevier Science Рейтинг: Цена: 28002.00 р. Наличие на складе: Поставка под заказ.
Описание: A guide to fabrication, characterization and applications in the field of hard coatings and wear-resistant surfaces. It offers an explanation of commercially oriented deposition technology, from traditional vacuum-based thin-film techniques such as evaporation, sputter deposition, and chemical vapor deposition, to various thermal spraying methods.
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