Immunotherapy in Transplantation: Principles and Practice, Kaplan

Автор: Nicholas Torpey
Название: Renal transplantation
ISBN: 0199215669 ISBN-13(EAN): 9780199215669
Издательство: Oxford Academ
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Описание: A comprehensive guide to all aspects of renal transplantation, this handbook follows the admission of a renal failure patient, covering eligibility for transplant, guidelines for the transplant process and potential complications. It includes comprehensive background information, including immunology, tissue typing and donor management.

Автор: Dranoff
Название: Cancer Immunology and Immunotherapy
ISBN: 3642141358 ISBN-13(EAN): 9783642141355
Издательство: Springer
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Цена: 28734.00 р.
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Описание: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.

Автор: Ludewig Burkhard, Hoffmann Matthias W.
Название: Adoptive Immunotherapy / Methods and Protocols
ISBN: 1588294064 ISBN-13(EAN): 9781588294067
Издательство: Springer
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Цена: 24456.00 р.
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Описание: An authoritative collection of optimal techniques for producing and characterizing the immunologically active cells and effector molecules now gaining wide use in the clinical treatment of patients. Taking advantage of the latest technologies, the authors present readily reproducible experimental protocols for the study of dendritic cells, T cells, monoclonal antibodies, and bone marrow transplantation. The emphasis is on preclinicical and clinical applications and on the progress of selected approaches in clinical trials. Additional chapters cover the molecular definition of target antigens, mathematical modeling approaches to immunotherapy, and the utilization of regulatory T cells. The protocols make it possible to study the adoptive transfer of tailored antigen-specific immune cells and to improve the clinical application of adoptive immunotherapy.

Автор: George C. Prendergast
Название: Cancer Immunotherapy,
ISBN: 0123942969 ISBN-13(EAN): 9780123942968
Издательство: Elsevier Science
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Цена: 16169.00 р.
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Описание: There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles.

Автор: Mckay, D B
Название: Kidney transplantation
ISBN: 144191689X ISBN-13(EAN): 9781441916891
Издательство: Springer
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Цена: 11878.00 р.
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Описание:

Kidney Transplantation: A Guide to the Care of Transplant Recipients is an easy to read, up to date, clinical resource written by experts in the field of kidney transplantation. The book explains how donors and recipients are selected for transplantation, how the surgical procedure is performed, and how the experts recognize and treat rejection.

Автор: Hamilton David
Название: A History of Organ Transplantation
ISBN: 0822944138 ISBN-13(EAN): 9780822944133
Издательство: Mare Nostrum (Eurospan)
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Цена: 10672.00 р.
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Описание: Foreword by Clyde Barker and Thomas E. Starzl A History of Organ Transplantation is a comprehensive and ambitious exploration of transplant surgery - which, surprisingly, is one of the longest continuous medical endeavors in history. Moreover, no other medical enterprise has had so many multiple interactions with other fields, including biology, ethics, law, government, and technology. Exploring the medical, scientific, and surgical events that led to modern transplant techniques, Hamilton argues that progress in successful transplantation required a unique combination of multiple methods, bold surgical empiricism, and major immunological insights in order for surgeons to develop an understanding of the body's most complex and mysterious mechanisms.  Surgical progress was nonlinear, sometimes reverting and sometimes significantly advancing through luck, serendipity, or helpful accidents of nature.       The first book of its kind, A History of Organ Transplantation examines the evolution of surgical tissue replacement from classical times to the medieval period to the present day. This well-executed volume will be useful to undergraduates, graduate students, scholars, surgeons, and the general public. Both Western and non-Western experiences as well as folk practices are included.

Автор: Andrea A. Zachary (Editor), Mary S. Leffell
Название: Transplantation Immunology: Methods and Protocols (Methods in Molecular Biology)
ISBN: 1627034927 ISBN-13(EAN): 9781627034920
Издательство: Springer
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Цена: 23757.00 р.
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Описание: PART I: Overview Chapters1. Alloreactivity

Sidonia B.G. Eckle, Jamie Rossjohn, and James McCluskey

2. Antibodies in Transplantation: The Effects of HLA and Non-HLA Antibody
Binding and Mechanisms of Injury

Nicole M. Valenzuela and Elaine F. Reed

3. Cell Mediated Rejection

Kathryn J Wood, Masaaki Zaitsu and Ryoichi Goto

4. Transplantation Tolerance

Colin Brinkman, Bryna Burrell, Joseph Scalea, and Jonathan Bromberg

5. Composite Tissue Transplantation

Gerald Brandacher

6. Transplantation of the Sensitized Patient: Histocompatibility Testing

Robert A. Montgomery, Mary S. Leffell, and Andrea A. Zachary

7. Thoracic Organ Transplantation: Laboratory Methods

Jignesh K. Patel and Jon A. Kobashigawa

PART II: Methods Chapters

8. HLA Typing by Sequence Specific Primers

Mike Bunce, Biofortuna and Ben Passey, Biofortuna

9. Human Leukocyte Antigen (HLA) Typing By DNA Sequencing

Ana Lazaro, Bin Tu, Ruyan Yang, Yi Xiao, Kanthi Kariyawasam, Jennifer Ng, Carolyn and Katovich Hurley

10. Next-Generation HLA Sequencing using the 454 GS FLX System

Elizabeth A. Trachtenberg and Cherie L. Holcomb

11. Chimerism Testing by Quantitative PCR Using Indel Markers

Ketevan Gendzekhadze, Laima Gaidulis, and David Senitzer

12. Gene-specific PCR Typing of Killer Cell Immunoglobulin-like Receptors (KIR)

Raja Rajalingam and Elham Ashouri

13. Complement-dependent Cytotoxicity Crossmatch

Jeremy Ryan Peсa, Donna Fitzpatrick, and Susan L. Saidman

14. Lymphocyte Crossmatching by Flow Cytometry

Robert A. Bray

15. Solid Phase Assay Measuring C4d Deposition to Determine Complement Fixation by HLA Specific Antibodies

John D Smith and Marlene L Rose

16. C1q Assay for the Detection of Complement Fixing Antibody to HLA Antigens

Ge Chen and Dolly B. Tyan

17. Tetramer Staining for the Detection of HLA-specific B cells

Donna P. Lucas, Mary S. Leffell, and Andrea A. Zachary

18. A Flow Cytometric Crossmatch Test Using Endothelial Precursor Cells Isolated from Peripheral Blood

Annette M. Jackson, Donna P. Lucas, Jessica L. Badders

19. The Detection of Antibodies to the Angiotensin II-Type 1 Receptor in Transplantation

Duska Dragun

20. Detection of Antibodies to Self-antigens (K-alpha 1 Tubulin, Collagen I, II, IV and V Myosin and Vimentin) by Enzyme-Linked Immunosorbent Assay (ELISA)

Nayan J. Sarma, Venkataswarup Tiriveedhi, and T. Mohanakumar

21. Cylex ImmuKnow Cell Function Assay

Adriana Zeevi and John Lunz

22. Detection of Intracellular Cytokines

Nancy L. Reinsmoen and Chih-Hung Lai

23. Tolerogenic Dendritic Cells and Induction of T Suppresson Cells in Transplant Recipients

George Vlad and Nicole Suciu-Foca

24. Discovery and Customized Validation of Antibody Targets by Protein Arrays and Indirect ELISA

Tara K. Sigdel, and Minnie. M. Sarwal

25. RNA Purification and Expression Analysis using Microarrays and RNA Deep Sequencing

Steven R. Head, Tony Mondala, Terri Gelbart, and Phillip Ordoukhanian

Автор: Barrett
Название: Clinical Practice Of Stem Cell Transplantation
ISBN: 1899066705 ISBN-13(EAN): 9781899066704
Издательство: Informa
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Цена: 28595.00 р.
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Описание: Featuring contributions from over 50 internationally recognized authorities, this text encompasses all types of bone marrow and peripheral blood cell transplantation. It describes malignant and non-malignant disorders, infections and complications of treatment. The text is illustrated in colour throughout and tables, checklists and flow charts summarize diagnostic criteria and treatment protocols.

Автор: Stock
Название: Hepatocyte Transplantation
ISBN: 1493965042 ISBN-13(EAN): 9781493965045
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume features up-to-date protocols for the isolation, preservation, and validation of various cell sources comprising large and small animal models, examining the impact of cell transplantation on acute and chronic liver diseases. Hepatocyte Transplantation: Methods and Protocols guides readers through laboratory protocols for the generation of humanized livers for the assessment of biological actions in vivo and techniques to monitor cell engraftment after cell transplantation in vivo are described and procedures for computational analyses of hepatocyte transplantation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and practical, Hepatocyte Transplantation: Methods and Protocols is an essential resource for researchers and clinicians to assess the biological as well as the therapeutic potential of hepatocyte transplantation.

Автор: Neuberger
Название: Liver Transplantation: Clinical Assessment and Management
ISBN: 1118277384 ISBN-13(EAN): 9781118277386
Издательство: Wiley
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Цена: 14256.00 р.
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Описание: Liver Transplantation: Clinical Assessment and Management is the perfect tool for all gastroenterologists, hepatologists and transplant surgeons managing patients with liver disease awaiting and undergoing transplantation.  Led by James N

Автор: Yotnda
Название: Immunotherapy of Cancer
ISBN: 1607617854 ISBN-13(EAN): 9781607617853
Издательство: Springer
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Цена: 23058.00 р.
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Описание: This book describes detailed procedures for trainees and experts in the area of basic, clinical science who wish to undertake their own cutting-edge immunotherapy studies. It includes coverage of pre-clinical models for cancer immunotherapy.