Pharmacogenomics in Drug Discovery and Development, Qing Yan
Автор: Yui-Wing Francis Lam Название: Pharmacogenomics, ISBN: 0123919185 ISBN-13(EAN): 9780123919182 Издательство: Elsevier Science Рейтинг: Цена: 11620.00 р. Наличие на складе: Поставка под заказ.
Описание: Includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. This book contains review questions for an analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward.
Автор: Bertino Joseph S Название: Pharmacogenomics an Introduction and Clinical Perspective ISBN: 0071741690 ISBN-13(EAN): 9780071741699 Издательство: McGraw-Hill Рейтинг: Цена: 13211.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Offers a coverage of all need-to-know topics, from individual molecules to systemic diseases, this book also provides an examination of the latest technologies that are constantly reshaping the field. It also includes general pharmacogenomics and pharmacogenetics concepts, including geneticvariation in signal transduction and targets.
Название: Applying Pharmacogenomics in Therapeutics ISBN: 1466582677 ISBN-13(EAN): 9781466582675 Издательство: Taylor&Francis Рейтинг: Цена: 27562.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Recent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a critical requirement. There is an unprecedented urgency for aspiring and practicing clinicians to become trained on how to interpret data from pharmacogenomic testing in preparation for the future of healthcare--i.e., personalized medicine.
Applying Pharmacogenomics in Therapeutics provides timely coverage of the principles, practice, and potential of pharmacogenomics and personalized medicine. Comprised of chapters contributed by well-established pharmacologists and scientists from US and Chinese academia and industry, this authoritative text:
Demonstrates how to apply the principles of pharmacogenomics and its biotechnologies in patient care
Depicts the use of genetic biomarkers in drug discovery and development, laboratory medicine, and clinical services
Describes the practice of pharmacogenomics in the treatment of cancers, cardiovascular diseases, neurologic and psychiatric disorders, and pulmonary diseases
Discusses the merging of pharmacogenomics and alternative medicine, as well as the integration of pharmacogenomics into pharmacoeconomics
Each chapter begins with the key concepts, followed by in-depth explorations of case reports or critical evaluations of genetic variants/biomarkers, and concludes with questions for self-examination.
Автор: Wu A. Название: Pharmacogenomic testing in current clinical practice ISBN: 1607612828 ISBN-13(EAN): 9781607612827 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: While the basic principles of personalized medicine and pharmacogenomics has been covered by numerous texts, there are none to date that focuses on the specific tests themselves that are in current clinical practice and those that are being proposed for implementation in the near future. Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory focuses almost entirely on the specifics of each test that is needed to implement these tests into a clinical laboratory. This volume presents the first compilation of the tests currently in routine clinical use. The chapter authors of this unique and invaluable title comprise a range of renowned authorities and investigators who have conducted the essential clinical trials necessary to justify pharmacogenomic testing today. The book is divided into four parts: Basic Concepts, Specific Pharmacogenomic Targets, Drugs that Cause Delayed Hypersensitivity, and Miscellaneous Drugs. Each author provides a pharmacologic background on the target drug, the need for pharmacogenomic testing, and how results can be translated into clinical decisions. Where appropriate, case studies are given to illustrate typical clinical scenarios. An extensive bibliography is provided so that the reader can refer to the original studies. This well-designed resource will appeal to clinical laboratory directors who are contemplating or assigned the task of establishing a pharmacogenomics laboratory and a wide range of clinicians who must interpret results of testing. Focused and immensely useful, Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory is a timely and outstanding contribution to the literature and will be instrumental in defining this rapidly growing field.
Название: Pharmacogenomics ISBN: 1588294404 ISBN-13(EAN): 9781588294401 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with HaploChIP, SNP genotyping in DNA pools, and PharmGKB, the pharmacogenetics and pharmacogenomics knowledge base. The methodologies for genotyping include denaturing high-performance liquid chromarography, pyrosequencing, kinetic-fluorescence detection, mass spectrometry, and TaqMan assay for insertion/deletions.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
