Oxidative Neural Injury, Sigrid C. Veasey

Автор: Jakob
Название: Oxidative Stress and Redox Regulation
ISBN: 9400757867 ISBN-13(EAN): 9789400757868
Издательство: Springer
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Цена: 25155.00 р.
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Описание: In this book examines how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.

Автор: J. Lunec
Название: Measuring in vivo Oxidative Damage: A Practical Approach
ISBN: 0471818488 ISBN-13(EAN): 9780471818489
Издательство: Wiley
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Цена: 44344.00 р.
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Описание: Oxygen free radicals have been implicated in a number of disease processes. This book provides a comprehensive guide for methodology in the analysis of biological samples. It is designed to help the clinical scientist evaluate the best method for their particular problem.

Автор: Armstrong Donald
Название: Oxidative Stress Biomarkers and Antioxidant Protocols
ISBN: 0896038505 ISBN-13(EAN): 9780896038509
Издательство: Springer
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Цена: 21661.00 р.
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Описание: Donald Armstrong updates and expands his highly praised Free Radical and Antioxidant Protocols (Humana, 1998) with a collection of new and valuable methods for evaluating the pertubations in cell function resulting from increased oxidative stress. Presented in a user-friendly, step-by-step format, these readily reproducible techniques cover both free radical-derived and antioxidant biomarkers. The methodologies demonstrated include ELISA, HPLC, infrared spectroscopy, gas chromatography-mass spectroscopy, immunoblotting, electroelution fractionation, isoelectric focusing, voltametry, and electron paramagnetic resonance imaging. Special emphasis is given to the separation of complex mixtures of plant antioxidants, soft drug design to protect from toxic oxidative metabolites, in vitro oxidation conditions, and correcting for random measurement error to improve statistical interpretation. A soon-to-be-published companion volume, Oxidants and Antioxidants: Ultrastructural and Molecular Biology Protocols (0-89603-851-3), contains state-of-the-art molecular and ultrastructural methods that expand the total number of protocols to 109 assays.

Автор: S.H. Parvez; Peter Riederer
Название: Oxidative Stress and Neuroprotection
ISBN: 3709117364 ISBN-13(EAN): 9783709117361
Издательство: Springer
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Цена: 30745.00 р.
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Описание: This book deals with basic and clinical aspects of monoamine oxidase (MAO) subtypes A and B highlighting its importance in neurological and psychiatric diseases. Consequently the therapeutic actions of MAO-A and -B inhibitors in Parkinson’s disease (PK) and depression are the focus of several chapters. As MAO is the basis of the development of the "oxidative stress hypothesis" of PD, several chapters are devoted to iron and iron-induced oxidative stress in various experimental studies and clinical conditions. Based on these findings, new compounds have been developed which not only block MAO, but are in addition, either inhibitors of acetylcholine esterase or have iron chelating properties. The aspect of "preclinical" and "clinical" neuro protection as well as MAO neuroprotection are additional topics covered in this book. MAO, iron and neuroprotection are seen in the framework of general anti Parkinson’s therapy with chapters on levodopa, dopaminergic receptor agonists and clinical issues.

Автор: Natan Gadoth; Hans Hilmar G?bel
Название: Oxidative Stress and Free Radical Damage in Neurology
ISBN: 1617797162 ISBN-13(EAN): 9781617797163
Издательство: Springer
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Цена: 28732.00 р.
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Описание: This book focuses on clinical and research issues regarding the interplay of free radicals and the human nervous system. Its comprehensive coverage extends to numerous antioxidants and their possible therapeutic role in neurological disorders.