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Proteases and Their Receptors in Inflammation, Nathalie Vergnolle; Michel Chignard


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Автор: Nathalie Vergnolle; Michel Chignard
Название:  Proteases and Their Receptors in Inflammation
ISBN: 9783034803427
Издательство: Springer
Классификация:


ISBN-10: 3034803427
Обложка/Формат: Paperback
Страницы: 300
Вес: 0.50 кг.
Дата издания: 2011
Серия: Progress in Inflammation Research
Язык: English
Иллюстрации: Biography
Размер: 234 x 156 x 17
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:

Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest. In inflamed tissues, proteases can have a microbial and/or host origin and are involved not only in tissue remodeling, but also in specific signaling to resident or inflammatory cells, thereby contributing to the innate immune response.

This volume presents all advances in our knowledge of the role proteases and their inhibitors play in various diseases associated with inflammatory response. Mechanisms involved in protease signaling to cells are presented, and the different types of proteases that are present at inflammatory sites and their effects on the course of inflammation are discussed. Finally, the evidence for considering proteases and their receptors as potential molecular targets for therapeutic interventions in the treatment of inflammatory diseases is discussed in the context of specific organ inflammatory pathologies (the lung, gastrointestinal tract, skin, joints, etc.).




Immune Receptors

Автор: Rast
Название: Immune Receptors
ISBN: 1617791385 ISBN-13(EAN): 9781617791383
Издательство: Springer
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Цена: 20263.00 р.
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Описание: Immunology has made significant progress in the past decade, driven forward by rapidly advancing technology and a renewed interest in the vast realm of innate immunity. The receptors that mediate these functions are at the front lines of both protective and regulative roles of the immune system.  In Immune Receptors: Methods and Protocols, expert researchers present a variety of experimental approaches to the characterization of immune receptors and the cell biology that mediates their functions.  These include imaging techniques that aim to understand receptor localization and trafficking, techniques to measure receptor-ligand interactions, strategies to identify novel ligands and methods to analyze downstream receptor signaling, as well as strategies for genomic and proteomic characterization of receptor repertoires. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immune Receptors: Methods and Protocols offers technical descriptions and protocols that will be useful both to investigators who are interested in carrying out these procedures and to those who seek a deeper understanding of the bench science that lies behind the immunology literature.

Central Nervous System Diseases and Inflammation

Автор: Lane
Название: Central Nervous System Diseases and Inflammation
ISBN: 0387738932 ISBN-13(EAN): 9780387738932
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Focusing on inflammatory CNS disease, this book explores how chemokines affect disease. It contains four sections which revolve around areas of interest within the field of neuroimmunology, virology, pharmacology and disease.


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