Cell Fusion in Health and Disease, Thomas Dittmar; Kurt S. Z?nker
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Автор: Dittmar Название: Cell fusion in health and disease ISBN: 9400707622 ISBN-13(EAN): 9789400707627 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Although cell fusion is an omnipresent process in life, to date considerably less is still known about the mechanisms and the molecules being involved in this biological phenomenon in higher organisms. In Cell Fusion in Health and Disease Vol 1 & Vol 2 leading experts will present up-to-date overviews about cell fusion in physiological and patho-physiological processes, which further covers the current knowledge about cell fusion-mediating molecules. Volume 1 deals with Cell Fusion in Health and will cover aspects of cell fusion in fertilization, placentation, in C. elegans, in skeletal muscle development and tissue repair, and the use of cell fusion for cellular reprogramming and cancer vaccine development. Volume 2 focuses on Cell Fusion in Disease with a particular emphasis on the role of cell fusion in cancer development and progression. Thus, Cell Fusion in Health and Disease Vol 1 & Vol 2 represents a state-of-the-art work for researchers, physicians or professionals being interested in the biological phenomenon of cell fusion and beyond.
Автор: Thomas Dittmar; Kurt S. Z?nker Название: Cell Fusion in Health and Disease ISBN: 9400735715 ISBN-13(EAN): 9789400735712 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This 2-volume set covers the processes of cell fusion in health and disease, including fertilization, placentation, and cell fusion in cellular reprogramming and cancer vaccine development, and on the role of cell fusion in cancer development and progression.
Автор: Seino Название: Pancreatic Beta Cell in Health and Disease ISBN: 4431998373 ISBN-13(EAN): 9784431998372 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This book provides a comprehensive review of the beta cell in health and disease.
Автор: Plichta Название: Munros Statistical methods health care 6E ISBN: 1451187947 ISBN-13(EAN): 9781451187946 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 13556.00 р. Наличие на складе: Поставка под заказ.
Описание: This text provides students with a solid foundation for understanding data analysis and specific statistical techniques. Focusing on the most current and frequently used statistical methods in today's health care literature, the book covers essential material for a variety of program levels including in-depth courses beyond the basic statistics course. Well-organized, clear text discussions and great learning tools help students overcome the complexities and fully comprehend the concepts of this often intimidating area of study.
Автор: Pitt, Geoffrey S. Название: Ion Channels in Health and Disease ISBN: 0128020024 ISBN-13(EAN): 9780128020029 Издательство: Elsevier Science Рейтинг: Цена: 13473.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Ion Channels in Health and Disease provides key insight to allow researchers to generate discoveries across disease states. A single resource that integrates disparate areas of biology and disease ion channel biology, this publication includes cross-referencing for disease, channels, and tissues. Offers a broad view of research of interest to early and experienced researchers across biological and biomedical research.
Автор: Stefan Jentsch; Bernhard Haendler Название: The Ubiquitin System in Health and Disease ISBN: 3540851062 ISBN-13(EAN): 9783540851066 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The ubiquitin system plays an essential role in numerous cellular processes by controlling protein stability and function. An understanding of the mechanisms governing these processes is likely to allow the identification of novel targets for pharmacological intervention. This work covers the developments in this field.
Автор: Peter Quinn; Xiaoyuan Wang Название: Lipids in Health and Disease ISBN: 1402088302 ISBN-13(EAN): 9781402088308 Издательство: Springer Рейтинг: Цена: 41787.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Offers an account of the properties of the classes of lipids that are located in the membranes of various cells. This title presents a balanced perspective of what is known about the function of these lipids in healthy cells and tissues and what consequences follow malfunctions in their synthesis and metabolism.
Автор: Christian Rommel; Bart Vanhaesebroeck; Peter K. Vo Название: Phosphoinositide 3-kinase in Health and Disease ISBN: 3642265227 ISBN-13(EAN): 9783642265228 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: PI3K is at the forefront of drug development with the first clinical trials of PI3K pathway inhibitors in progress. This book offers an overview of some key discoveries in the PI3K area and their impact, and includes thoughts on the current state of the field.
Автор: Gael Cristofari Название: Human Retrotransposons in Health and Disease ISBN: 3319483439 ISBN-13(EAN): 9783319483436 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Retrotransposons and the Mammalian Germline.- L1 regulation in Mouse and Human Germ Cells.- Retrotransposon Contribution to Genomic Plasticity.- The Mobilization of Processed Transcripts in Germline and Somatic Tissues.- Neuronal Genome Plasticity: Retrotransposons, Environment and Disease.- Activity of Retrotransposons in Stem Cells and Differentiated Cells.- Environment, Cellular Signaling and L1 activity.- Retrotransposon-derived Regulatory Regions and Transcripts in Stemness.- Roles of Endogenous Retrovirus-encoded Syncytins in Human Placentation.- Alu-Alu Recombinations in Genetic Diseases.- Retrotransposon-driven Transcription and Cancer.- LINE-1 retrotransposons as Neoplastic Biomarkers.- Contribution of Retrotransposable Elements to Aging.
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