Автор: Lo Benny K. C. Название: Antibody Engineering / Methods and Protocols ISBN: 1588290921 ISBN-13(EAN): 9781588290922 Издательство: Springer Рейтинг: Цена: 24456.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A core collection of diverse cutting-edge techniques for the generation, expression, optimization, and characterization of recombinant antibodies. Readily reproducible protocols for lead generation range from the cloning of human immunoglobulin genes to the selection and generation of human recombinant antibodies by humanization approaches, molecular display technologies and transgenic animals. Procedures are also described on restructuring antibody leads into monovalent, multivalent, and bispecific binding fragments for a wide variety of in vivo applications. State-of-the-art technologies are described for the characterization of antigen-binding affinity and specificity with novel applications in radioimmunotargeting, cancer immunotherapy, drug abuse, and proteomics.
Автор: Proetzel Название: Antibody Methods and Protocols ISBN: 1617799300 ISBN-13(EAN): 9781617799303 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The rapidly growing field of antibody research is the result of many advancing technologies allowing current developments to take advantage of molecular engineering to create tailor-made antibodies. Antibody Methods and Protocols attempts to provide insight into the generation of antibodies using in vitro and in vivo approaches, as well as technical aspects for screening, analysis, and modification of antibodies and antibody fragments. The detailed volume is focused on basic protocols for isolating antibodies and, at the same time, it selects a range of specific areas with the aim of providing guides for the overall process of antibody isolation and characterization as well as protocols for enhancing classical antibodies and antibody fragments. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Antibody Methods and Protocols provides a broad and useful background to support ongoing efforts by novices and experts alike and encourages the development of new imaginative approaches to this vital area of study.
Автор: Robert Aitken (Ed.) Название: Antibody Phage Display ISBN: 1603273018 ISBN-13(EAN): 9781603273015 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Поставка под заказ.
Описание: Phage display technology has revolutionized approaches to the analysis of biomedical problems, impacting the fields of immunology, cell biology, biotechnology, pharmacology, and drug discovery. This title provides a resource that guides readers in the design and execution of experiments based around antibody phage display.
Автор: Howard Название: Basic Methods in Antibody Production & Charact. ISBN: 0849394457 ISBN-13(EAN): 9780849394454 Издательство: Taylor&Francis Цена: 10258.00 р. Наличие на складе: Поставка под заказ.
Описание: Written for researchers and professionals in the fields of biomedical research, immunology, biochemistry, molecular biology, pathology, and biotechnology, Basic Methods in Antibody Production and Characterization uses a cookbook approach to presenting the methods for the production, characterization, and use of antiboes. Antibodies described include polyclonal and monoclonal and those made by the phage display. Basic Methods in Antibody Production and Characterization focuses on specific aspects of antibodies and takes readers on a step-by-step process from antigen preparation to immunizations, adjuvants, screening, purification, storage, and applications.Introductory material accompanies each chapter, giving readers a better understanding of the methods and applications. Ample references arm researchers with many applications pertaining to the particular technology.
Автор: Antony S. Dimitrov (Ed.) Название: Therapeutic Antibodies ISBN: 1934115924 ISBN-13(EAN): 9781934115923 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Поставка под заказ.
Описание: Presents a set of protocols for the discovery and development of therapeutic antibodies, featuring sections focusing on recombinant antigens, antibody libraries, antibody discovery, antibody engineering and antibody preclinical development. This work is suitable for those investigating and participating in this therapeutic market segment.
Автор: McCafferty, John; Hoogenboom, Hennie; Chiswell, Da Название: Antibody Engineering A Practical Approach (Hardback) ISBN: 0199635927 ISBN-13(EAN): 9780199635924 Издательство: Oxford Academ Рейтинг: Цена: 13939.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recombinant DNA techniques have revolutionized the isolation and production of antibodies in recent years, and rapid changes have been made. The time is now ripe to assemble in a Practical Approach volume the protocols which allow the researcher to isolate a new antibody, analyse its properties, format the right antibody molecule or fragment, and produce it in usable quantitites.
Автор: Mohamed Al-Rubeai Название: Antibody Expression and Production ISBN: 9400736134 ISBN-13(EAN): 9789400736139 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers generation, optimization, characterization, production and applications of antibodies, offering theoretical background and describing methods for expression of antibody in microbial and animal cell cultures and transgenic animals and plants.
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