Описание: Presents information on proteins dependent upon Vitamin B6, PQQ or other quinones for function. This work contains sections focusing on the mechanisms of folding and addressing the molecular physiology and pathology of these families of proteins, which are of biomedical interest.
Описание: Since the first international meeting on Vitamin B6 involvement in catalysis took place in 1962, there have been periodic meetings every three or four years.
Автор: Peter K. Vogt; Stephen I. Reed Название: Cyclin Dependent Kinase (CDK) Inhibitors ISBN: 3642719430 ISBN-13(EAN): 9783642719431 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: More than 10 years ago, the discovery of cyclin-dependent ki- nases (Cdks) ushered in a new era in the understanding of cell proliferation and its control.
Автор: Hochstrasser, Mark Название: Hochstrasser-Ubiquitin-Dependent Protein Degradation V619 ISBN: 0128186674 ISBN-13(EAN): 9780128186671 Издательство: Elsevier Science Рейтинг: Цена: 26275.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Ubiquitination and Protein Stability - Part B, Volume 619, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors. Topics of note include chapters on Assays of SUMO protease function in mammalian cells, In vitro analysis of proteasome-associated USP14 activity for substrate degradation and deubiquitylation, Methods to study proteasome regulatory particle assembly, Native mass spectrometry approaches to study the proteasome, Single-molecule methods to study the ubiquitin-proteasome system, Assays for the function of ubiquitin in the mammalian endocytic pathway, and much more.
Provides the authority and expertise of leading contributors from an international board of authors
Presents the latest release in this series on enzymology
Автор: Gerhard Gross Название: Stem Cell-dependent Therapies ISBN: 3110298260 ISBN-13(EAN): 9783110298260 Издательство: Walter de Gruyter Цена: 31603.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Multipotent mesenchymal stem cells (MSCs) are a heterogeneous population of cells which reside in a variety of tissues. They differentiate into several mesodermal lineages, secrete a multitude of trophic factors and contribute to tissue homeostasis. MSCs are able to exert immunosuppressive activities by interfering with inflammatory cytokine production and with T- and B-cell proliferation. These immunomodulating properties make MSCs promising candidates for the treatment of chronic inflammatory and autoimmune disorders. There are, however, certain caveats involved including inappropriate migration of cells in the body, immune rejection, tumor formation, or graft versus host disease (GvHD). This book investigates the current state of the MSC-dependent therapy of chronic inflammatory disorders and autoimmune diseases. Among the covered topics are GvHD, chronic kidney, liver and lung disease, ischemic heart and inflammatory bowel disease, diabetes, osteoarthritis, various rheumatic and neurological disorders and, lastly, tumors and solid organ transplantations. This book also questions the immunoprivileged status of MSCs, discusses the therapeutic role of MSCs in experimental animal disease models and their translation to the corresponding human disorders, envisions a role for MSCs in tumor interventions and, lastly, describes a systems biology approach for stem cells and inflammation.
Автор: James D. Johnson, Michael J. Bround, Tobias Albrecht Название: Ca2+-dependent Signal Transduction ISBN: 161504664X ISBN-13(EAN): 9781615046645 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 9286.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Provides a review of the general principles of Ca2+ signal transduction and examples of some of the major Ca2+-dependent cellular processes. This volume also reviews the main sources of Ca2+ and the molecular effectors of Ca2+ signals, and provides some examples from the literature that illustrate how Ca2+ signalling works.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
