Basic Pharmacokinetics and Pharmacodynamics, Rosenbaum Sara E.
Старое издание
Автор: Alexander Vinks; Hartmut Derendorf; Johan Mouton ( Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics ISBN: 0387756124 ISBN-13(EAN): 9780387756127 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.
Описание: The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. www.springeronline.com
Автор: Nightingale Charles H Название: Antimicrobial Pharmacodynamics ISBN: 0824729250 ISBN-13(EAN): 9780824729257 Издательство: Taylor&Francis Рейтинг: Цена: 33686.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Antimicrobial Pharmacodynamics in Theory and Clinical Practice
Автор: Bauer Название: Handbook of clinical pharmacokinetics ISBN: 007142542X ISBN-13(EAN): 9780071425421 Издательство: McGraw-Hill Рейтинг: Цена: 6347.00 р. Наличие на складе: Поставка под заказ.
Описание: Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. It also features calculation methods, algorithms for choosing the best calculation method, and case studies.
Автор: Wolfgang Название: HB of Basic Pharmacokinetics.2004 ISBN: 1582120544 ISBN-13(EAN): 9781582120546 Издательство: McGraw-Hill Рейтинг: Цена: 6004.00 р. Наличие на складе: Поставка под заказ.
Описание: The classic textbook of principles and techniques for practitioners, researchers, and undergraduate and graduate students involved in various applications of pharmacokinetics. Spanning 38 detailed chapters and an appendix providing pharmacokinetic data profiles on more than 420 drugs, this book includes information that is both current and accurate. Presented in a manner that fosters clinical application, readers will gain an understanding of the more precise equations for determining pharmacokinetic values.
Автор: Boroujerdi, Mehdi|| Название: Pharmacokinetics and Toxicokinetics ISBN: 1482221349 ISBN-13(EAN): 9781482221343 Издательство: Taylor&Francis Рейтинг: Цена: 26030.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Pharmacokinetics and Toxicokinetics provides an overview of pharmacokinetics and toxicokinetics in a comprehensible, interrelated, and applied manner. It integrates the principles held in common by both fields through a logical and systematic approach.
The book presents mathematical descriptions of physiological processes employed in different approaches to PK/TK modeling. It focuses on emphasizing general principles and concepts, rather than isolated observations. Above all, the book is an effort to blend the pharmaceutical and toxicological aspects of both fields.
The systematic compilation of mathematical concepts and methodologies allows readers to decide on relevant concepts and approaches for their research, scientific or regulatory decisions, or for offering advance courses and seminars. This is an invaluable resource for scientists in the pharmaceutical sciences, clinical sciences, and environmental health sciences, as well as those involved in drug discovery and development.
Описание: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.
Автор: Mager Название: Systems Pharmacology and Pharmacodynamics ISBN: 3319445324 ISBN-13(EAN): 9783319445328 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: While systems biology and pharmacodynamics have evolved in parallel, there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline that is the interface between these two methods. This book is the first to cover the expertise from systems biology and pharmacodynamics researchers, describing how systems pharmacology may be developed and refined further to show practical applications in drug development. There is a growing awareness that pharmaceutical companies should reduce the high attrition in the pipeline due to insufficient efficacy or toxicity found in proof-of-concept and/or Phase II studies. Systems Pharmacology and Pharmacodynamics discusses the framework for integrating information obtained from understanding physiological/pathological pathways (normal body function system vs. perturbed system due to disease) and pharmacological targets in order to predict clinical efficacy and adverse events through iterations between mathematical modeling and experimentation.
Автор: Shargel Leon Название: Applied Biopharmaceutics & Pharmacokinetics, 7 ed. ISBN: 0071830936 ISBN-13(EAN): 9780071830935 Издательство: McGraw-Hill Рейтинг: Цена: 10294.00 р. Наличие на складе: Поставка под заказ.
Описание: The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics-now fully updated
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