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Pharmacokinetics in Drug Development, Bonate


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Цена: 25155.00р.
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При оформлении заказа до: 2025-07-28
Ориентировочная дата поставки: Август-начало Сентября
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Автор: Bonate
Название:  Pharmacokinetics in Drug Development
ISBN: 9783319390512
Издательство: Springer
Классификация:



ISBN-10: 3319390511
Обложка/Формат: Hardback
Страницы: 330
Вес: 0.68 кг.
Дата издания: 2016
Язык: English
Издание: 1st ed. 2016
Иллюстрации: 23 illustrations, color; 9 illustrations, black and white; xii, 330 p. 32 illus., 23 illus. in color.
Размер: 234 x 156 x 21
Читательская аудитория: General (us: trade)
Основная тема: Biomedicine
Подзаголовок: Problems and Challenges in Oncology, Volume 4
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: In this volume, the specific challenges and problems facing the evaluation of new oncology agents are explored with regards to pharmacokinetic, pharmacodynamic modeling and clinical pharmacology development strategies. This book delivers, with an emphasis on the oncology therapeutic area, the goals set in the first three volumes: namely – to provide clinical pharmacologists practical insights for the application of pharmacology, pharmacokinetics and pharmacodynamics for new drug development strategies. Pharmacokinetic-pharmacodynamic concepts for tyrosine kinases, the evaluation of cardiac repolarization prolongation through QTc interval effects, efficacy- and safety-response analyses to support new drug approvals, clinical and preclinical tumor growth modeling, and flat- vs weight-based dose selection are showcased from an oncology clinical pharmacologist’s point-of-view. Oncology development strategies are surveyed for new FDA-approvals to identify patterns in expectations at time of first approval. The special considerations necessary to address combination drug development, metronomics, biosimilars and breakthrough therapies are also presented.
Дополнительное описание: Overview of Oncology Drug Development.- A Global Perspective on First-In-Man Dose Selection: Oncology and Beyond.- Controversies in Oncology: Size-Based vs. Fixed Dosing.- Clinical QTc Assessment in Oncology.- Expediting Drug Development: Breakthrough The



Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

Автор: Alexander Vinks; Hartmut Derendorf; Johan Mouton (
Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics
ISBN: 0387756124 ISBN-13(EAN): 9780387756127
Издательство: Springer
Рейтинг:
Цена: 23757.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Introduction to Pharmacokinetics and Pharmacodynamics: The Quantitative Basis of Drug Therapy

Автор: Tozer
Название: Introduction to Pharmacokinetics and Pharmacodynamics: The Quantitative Basis of Drug Therapy
ISBN: 0781751497 ISBN-13(EAN): 9780781751490
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 7379.00 р.
Наличие на складе: Поставка под заказ.

Описание: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.

Handbook of clinical pharmacokinetics

Автор: Bauer
Название: Handbook of clinical pharmacokinetics
ISBN: 007142542X ISBN-13(EAN): 9780071425421
Издательство: McGraw-Hill
Рейтинг:
Цена: 6347.00 р.
Наличие на складе: Поставка под заказ.

Описание: Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. It also features calculation methods, algorithms for choosing the best calculation method, and case studies.

Pharmacokinetics in Drug Development / Clinical Study Design and Analysis (Volume 1)

Автор: Bonate Peter, Howard Danny
Название: Pharmacokinetics in Drug Development / Clinical Study Design and Analysis (Volume 1)
ISBN: 0971176744 ISBN-13(EAN): 9780971176744
Издательство: Springer
Рейтинг:
Цена: 30745.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.

Pharmacokinetics in Drug Development / Regulatory and Development Paradigms (Volume 2)

Автор: Bonate Peter, Howard Danny
Название: Pharmacokinetics in Drug Development / Regulatory and Development Paradigms (Volume 2)
ISBN: 0971176736 ISBN-13(EAN): 9780971176737
Издательство: Springer
Цена: 22354.00 р.
Наличие на складе: Поставка под заказ.

Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.

Pharmacokinetics in Drug Discovery and Development

Автор: Schoenwald
Название: Pharmacokinetics in Drug Discovery and Development
ISBN: 1566769736 ISBN-13(EAN): 9781566769730
Издательство: Taylor&Francis
Рейтинг:
Цена: 29093.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: From basic principles to industrial and regulatory applications to clinical and research applications, this book reviews the subspecialties in the field of pharmacokinetics. It covers topics such as PK/PD approaches, clinical pharmacokinetic monitoring, population pharmacokinetics, and linear systems approaches.


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