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Cancer Biomarkers in Body Fluids, Dakubo


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Цена: 25155.00р.
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Автор: Dakubo
Название:  Cancer Biomarkers in Body Fluids
ISBN: 9783319015798
Издательство: Springer
Классификация:


ISBN-10: 3319015796
Обложка/Формат: Hardback
Страницы: 299
Вес: 0.64 кг.
Дата издания: 2016
Язык: English
Издание: 1st ed. 2016
Иллюстрации: 30 tables, color; 44 illustrations, color; 2 illustrations, black and white; xvi, 299 p. 46 illus., 44 illus. in color.
Размер: 234 x 156 x 19
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Подзаголовок: Principles
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The molecular and genetic signatures of cancer are represented in the peripheral circulation and other body fluids, giving rise to the “liquid biopsy” concept. This new paradigm of molecular profiling of cancer cells offers several advantages over traditional tissue biopsy. It is convenient, noninvasive, conforms to current clinical practice, enables real time disease monitoring and the study of tumor evolution, can easily be sampled multiple times, and this sample is more representative of the heterogeneous cancer cells than biopsy sampling. Indeed, all aspects of cancer molecular genetic information, stemming from DNA (both nuclear and mitochondria), RNA (coding and noncoding), peptides and proteins, metabolites and lipids are present in body fluids as free, cell surface bound or enclosed in membrane vesicles, and are being harnessed for disease management. Additionally, circulating tumor, and tumor stem cells provide prognostic information, and also enable the study of the intricate molecular processes associated with metastasis and drug resistance. This treatise deals with the general principles of the molecular pathology of cancer, and its associated imprints in circulation. The transitional process from discovery, prototype development, translational research, to product development can be complex and costly. The critical path to biomarker development and qualification for successful use in drug development is detailed herein as well.This book is of interest to Cancer Researchers, Oncologists, Clinicians, Surgeons, Medical Students, Nurses, Diagnostic Laboratories, and Pharmaceutical Industries.??
Дополнительное описание: PART ONE: SYNOPSIS OF CANCER BIOMARKERS Chapter 1: An Overview of Cancer Biomarkers Chapter 2: Bodily Fluids and Cancer Biomarkers PART TWO: CANCER BIOMARKERS IN CIRCULATION Chapter 3: Circulating Nonspecific Cancer Nucleic Acids Chapter 4: Circulating Ca



Cancer Biomarkers. 2007

Автор: Harndan
Название: Cancer Biomarkers. 2007
ISBN: 0471745162 ISBN-13(EAN): 9780471745167
Издательство: Wiley
Рейтинг:
Цена: 21376.00 р.
Наличие на складе: Поставка под заказ.

Описание: Tools, techniques, and progress in cancer biomarkers discovery The completion of a number of gene sequencing projects, recent advances in genomic and proteomic technologies, and the availability of powerful bioinformatics tools have led to promising new avenues and approaches in the search for cancer biomarkers.

Biomarkers in Oncology

Автор: Lenz H. G.
Название: Biomarkers in Oncology
ISBN: 1441997547 ISBN-13(EAN): 9781441997548
Издательство: Springer
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Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This integrated book covers the entire spectrum of cancer biomarkers in development and clinical use. Predictive and prognostic markers are explored in the context of colon cancer, breast cancer, lung cancer, prostate cancer, and GIST. International experts provide insight into toxicity markers and surrogate markers. Attention is also given to biomarker assay development, validation, and strategies. A powerful tool for determining decisions on therapy, selecting drug regimens, monitoring the efficacy of treatment, and performing individualized surveillance, biomarkers represent the forefront of cancer research and treatment. As these technologies become increasingly available for clinical use, this book will be an essential resource for oncologists and translational researchers.

Cancer Biomarkers in Body Fluids

Автор: Gabriel D. Dakubo
Название: Cancer Biomarkers in Body Fluids
ISBN: 3319483595 ISBN-13(EAN): 9783319483597
Издательство: Springer
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Цена: 32142.00 р.
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Описание: This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry.

Handbook of Therapeutic Biomarkers in Cancer

Название: Handbook of Therapeutic Biomarkers in Cancer
ISBN: 9814364657 ISBN-13(EAN): 9789814364652
Издательство: Taylor&Francis
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Цена: 21437.00 р.
Наличие на складе: Поставка под заказ.

Описание: In this volume, a team of internationally recognized experts provide an in-depth description of therapeutic biomarkers across a broad area of cancer research and oncology. With a wealth of information to specific therapies, each chapter focuses on a class of targeted chemotherapy agents. The book describes established and evolving diagnostic tests for therapeutic biomarkers that predict benefit, response, resistance, or drug side effects from specific therapeutic interventions. This volume is an essential handbook for health professionals and scientists researching current applicable biomarkers in oncology.

Biomarkers in Breast Cancer

Автор: Giampietro Gasparini; Daniel F. Hayes
Название: Biomarkers in Breast Cancer
ISBN: 1617374369 ISBN-13(EAN): 9781617374364
Издательство: Springer
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Цена: 34799.00 р.
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Описание: Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators.

The Handbook of biomarkers

Автор: Jain K.K.
Название: The Handbook of biomarkers
ISBN: 160761684X ISBN-13(EAN): 9781607616849
Издательство: Springer
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Цена: 26122.00 р.
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Описание: This handbook describes many different types of biomarkers and their discovery. It also presents the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials.


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