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Handbook of Therapeutic Biomarkers in Cancer, 



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Название:  Handbook of Therapeutic Biomarkers in Cancer   (Шерри Янг: Руководство по терапевтическим биомаркерам рака)
Издательство: Taylor&Francis
Классификация:
Медицинский диагностика
Онкология

ISBN: 9814364657
ISBN-13(EAN): 9789814364652
ISBN: 981-436465-7
ISBN-13(EAN): 978-981-436465-2
Обложка/Формат: Hardback
Страницы: 518
Вес: 0.861 кг.
Дата издания: 20.06.2013
Серия: Medicine
Язык: ENG
Иллюстрации: 20 pages of color scattered through book; 20 illustrations, color; 18 illustrations, black and white
Размер: 229 x 152
Читательская аудитория: Postgraduate, research & scholarly
Ключевые слова: Oncology, MEDICAL / Oncology,MEDICAL / Pathology,SCIENCE / Life Sciences / Cell Biology
Рейтинг:
Поставляется из: Англии
Описание: In this volume, a team of internationally recognized experts provide an in-depth description of therapeutic biomarkers across a broad area of cancer research and oncology. With a wealth of information to specific therapies, each chapter focuses on a class of targeted chemotherapy agents. The book describes established and evolving diagnostic tests for therapeutic biomarkers that predict benefit, response, resistance, or drug side effects from specific therapeutic interventions. This volume is an essential handbook for health professionals and scientists researching current applicable biomarkers in oncology.
Дополнительное описание:




Cancer Biomarkers in Body Fluids

Автор: Dakubo
Название: Cancer Biomarkers in Body Fluids
ISBN: 3319015796 ISBN-13(EAN): 9783319015798
Издательство: Springer
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Цена: 17476 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The molecular and genetic signatures of cancer are represented in the peripheral circulation and other body fluids, giving rise to the “liquid biopsy” concept. This new paradigm of molecular profiling of cancer cells offers several advantages over traditional tissue biopsy. It is convenient, noninvasive, conforms to current clinical practice, enables real time disease monitoring and the study of tumor evolution, can easily be sampled multiple times, and this sample is more representative of the heterogeneous cancer cells than biopsy sampling. Indeed, all aspects of cancer molecular genetic information, stemming from DNA (both nuclear and mitochondria), RNA (coding and noncoding), peptides and proteins, metabolites and lipids are present in body fluids as free, cell surface bound or enclosed in membrane vesicles, and are being harnessed for disease management. Additionally, circulating tumor, and tumor stem cells provide prognostic information, and also enable the study of the intricate molecular processes associated with metastasis and drug resistance. This treatise deals with the general principles of the molecular pathology of cancer, and its associated imprints in circulation. The transitional process from discovery, prototype development, translational research, to product development can be complex and costly. The critical path to biomarker development and qualification for successful use in drug development is detailed herein as well.This book is of interest to Cancer Researchers, Oncologists, Clinicians, Surgeons, Medical Students, Nurses, Diagnostic Laboratories, and Pharmaceutical Industries.??

Oxidative Stress Biomarkers and Antioxidant Protocols

Автор: Armstrong Donald
Название: Oxidative Stress Biomarkers and Antioxidant Protocols
ISBN: 0896038505 ISBN-13(EAN): 9780896038509
Издательство: Springer
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Цена: 14492 р.
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Описание: Donald Armstrong updates and expands his highly praised Free Radical and Antioxidant Protocols (Humana, 1998) with a collection of new and valuable methods for evaluating the pertubations in cell function resulting from increased oxidative stress. Presented in a user-friendly, step-by-step format, these readily reproducible techniques cover both free radical-derived and antioxidant biomarkers. The methodologies demonstrated include ELISA, HPLC, infrared spectroscopy, gas chromatography-mass spectroscopy, immunoblotting, electroelution fractionation, isoelectric focusing, voltametry, and electron paramagnetic resonance imaging. Special emphasis is given to the separation of complex mixtures of plant antioxidants, soft drug design to protect from toxic oxidative metabolites, in vitro oxidation conditions, and correcting for random measurement error to improve statistical interpretation. A soon-to-be-published companion volume, Oxidants and Antioxidants: Ultrastructural and Molecular Biology Protocols (0-89603-851-3), contains state-of-the-art molecular and ultrastructural methods that expand the total number of protocols to 109 assays.

Cancer Biomarkers

Название: Cancer Biomarkers
ISBN: 1578087619 ISBN-13(EAN): 9781578087617
Издательство: Taylor&Francis
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Цена: 12540 р.
Наличие на складе: Поставка под заказ.

Описание: This unique synthesis of chapters from top experts in their fields, targets the very important and upcoming area of cancer biomarkers and the need for better and more rigorous design and clinical trial. The book covers several aspects of cancer molecular markers from innovation, screening, controversies and future directions. The primary target audience for the book includes PhD and MD students, researchers, biologists, medical doctors and professionals who are interested in mechanistic studies on cancer diagnosis and translational benefits from personalized cancer treatment using the new era of biomarkers.

The Handbook of biomarkers

Автор: Jain K.K.
Название: The Handbook of biomarkers
ISBN: 160761684X ISBN-13(EAN): 9781607616849
Издательство: Springer
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Цена: 17476 р.
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Описание: This handbook describes many different types of biomarkers and their discovery. It also presents the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials.

Biomarkers of Disease

Автор: Edited by Andrew K. Trull
Название: Biomarkers of Disease
ISBN: 0521811023 ISBN-13(EAN): 9780521811026
Издательство: Cambridge Academ
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Цена: 23002 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This publication takes a critical, evidence-based look at the efficacy of diagnostic tests which are increasingly being used to evaluate organ damage and dysfunction. The use of biomarkers is growing, with a steady stream of products being brought out by the pharmaceutical industry. Some of these assist in diagnosis, others provide a means of monitoring the state of progression of disease and the effectiveness of therapeutic options. However, in many cases the evidence which supports the use of these methods as opposed to traditional biochemical tests has not yet been demonstrated, and it is intended that this volume will help clarify the strengths and weaknesses of using these biomarkers across a wide range of applications and in the various organs of the body. This approach will provide pathologists, clinical biochemists and medical laboratory scientists with an invaluable overview of the diverse applications of biomarkers in medicine.

Biomarkers of disease

Название: Biomarkers of disease
ISBN: 0521088607 ISBN-13(EAN): 9780521088602
Издательство: Cambridge Academ
Рейтинг:
Цена: 5412 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This publication takes a critical, evidence-based look at the efficacy of diagnostic tests which are increasingly being used to evaluate organ damage and dysfunction. The use of biomarkers is growing, with a steady stream of products being brought out by the pharmaceutical industry. Some of these assist in diagnosis, others provide a means of monitoring the state of progression of disease and the effectiveness of therapeutic options. However, in many cases the evidence which supports the use of these methods as opposed to traditional biochemical tests has not yet been demonstrated, and it is intended that this volume will help clarify the strengths and weaknesses of using these biomarkers across a wide range of applications and in the various organs of the body. This approach will provide pathologists, clinical biochemists and medical laboratory scientists with an invaluable overview of the diverse applications of biomarkers in medicine.

Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma

Автор: Murphy
Название: Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma
ISBN: 1607614324 ISBN-13(EAN): 9781607614326
Издательство: Springer
Рейтинг:
Цена: 21412 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book describes both the technologies used in the discovery of melanoma biomarkers and the clinical application of these biomarkers for diagnosis and staging of disease, determination of prognosis, treatment planning, monitoring of response to therapy, identification of novel therapeutic targets and drug development. A broad range of biomarkers (DNA/chromosomal, mRNA, microRNA, mitochondrial DNA, epigenetic and protein) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably play a greater role in the management of patients with this disease. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma is an essential resource for oncologists, dermatologists, dermatopathologists, general pathologists with an interest in melanoma, and melanoma researchers.

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

Автор: Ritsner
Название: The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes
ISBN: 9048182093 ISBN-13(EAN): 9789048182091
Издательство: Springer
Рейтинг:
Цена: 13106 р.
Наличие на складе: Поставка под заказ.

Описание: This four-volume handbook offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The contributors are internationally and nationally recognized experts from 16 countries.

Название: Handbook Of Biomarkers & Personaliz
ISBN: 1498762581 ISBN-13(EAN): 9781498762588
Издательство: Taylor&Francis
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Цена: 22990 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Providesperspective, covers recent developments in technologies that have enabled the expanded use of biomarkers, discusses biomarker characterization and validation, and applications throughout the discovery-development continuum, including Companion Diagnostic ( CDX) development.

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

Название: The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes
ISBN: 904818133X ISBN-13(EAN): 9789048181339
Издательство: Springer
Рейтинг:
Цена: 13106 р.
Наличие на складе: Поставка под заказ.

Описание: Organized into four interconnected volumes, this handbook offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry.

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

Автор: Ritsner Michael S. (Ed.)
Название: The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes
ISBN: 904812297X ISBN-13(EAN): 9789048122974
Издательство: Springer
Рейтинг:
Цена: 15427 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer's disease, epilepsy, alcoholism, substance abuse and others are one of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances.

This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: "Neuropsychological Endophenotypes and Biomarkers" (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), "Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers", "Metabolic and Peripheral Biomarkers" and "Molecular Genetic and Genomic Markers". The contributors are internationally and nationally recognized researchers and experts from 16 countries.

This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

Автор: Michael S. Ritsner (Ed.)
Название: The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes
ISBN: 1402098308 ISBN-13(EAN): 9781402098307
Издательство: Springer
Рейтинг:
Цена: 15728 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer's disease, epilepsy, alcoholism, substance abuse and others are one of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances.

This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: "Neuropsychological Endophenotypes and Biomarkers" (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), "Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers", "Metabolic and Peripheral Biomarkers" and "Molecular Genetic and Genomic Markers". The contributors are internationally and nationally recognized researchers and experts from 16 countries.

This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of p ychiatry, neurology, psychology and mental health.


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