Genome Editing, Turksen

Автор: Yamamoto, Takashi
Название: Targeted Genome Editing Using Site-Specific Nucleases
ISBN: 443155226X ISBN-13(EAN): 9784431552260
Издательство: Springer
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Цена: 22359 р.
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Описание: This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which have received much attention in recent years as breakthrough technologies. Genome editing with engineered nucleases allows us to precisely change the target genome of living cells and is a powerful way to control functional genes. It is feasible in almost all organisms ranging from bacteria to plants and animals, as well as in cultured cells such as ES and iPS cells. Various genome modifications have proven successful, including gene knockout and knock-in experiments with targeting vectors and chromosomal editing. Genome editing technologies hold great promise for the future, for example in biomedical research, clinical medicine, and generation of crops and livestock with desirable traits. A wide range of readers will find this book interesting, and with its focus on applications in a variety of organisms and cells, the book will be valuable for life scientists in all fields.

Автор: Nasheuer
Название: Genome Stability and Human Diseases
ISBN: 9048134706 ISBN-13(EAN): 9789048134700
Издательство: Springer
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Цена: 28734 р.
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Описание: This comprehensive overview discusses cancer cell biology in relation to Genome stability and Cell cycle regulation. Chapters are devoted to genome stability and anti-cancer drug targets, chromatin factors, DNA repair, apoptosis and other key areas of research.

Автор: Nasheuer
Название: Genome Stability and Human Diseases
ISBN: 9400731256 ISBN-13(EAN): 9789400731257
Издательство: Springer
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Цена: 28732 р.
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Описание: This comprehensive overview discusses cancer cell biology in relation to Genome stability and Cell cycle regulation. Chapters are devoted to genome stability and anti-cancer drug targets, chromatin factors, DNA repair, apoptosis and other key areas of research.

Автор: Hirohisa Hirai; Hiroo Imai; Yasuhiro Go
Название: Post-Genome Biology of Primates
ISBN: 4431547223 ISBN-13(EAN): 9784431547228
Издательство: Springer
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Цена: 23508 р.
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Описание: Today, researchers in primatology and anthropology have access to a wealth of genome information, opening new insights into primate studies. This book recounts the current state of knowledge, and offers directions for the future of primate genome studies.

Автор: Dirk-Henner Lankenau
Название: Genome Integrity
ISBN: 3642072267 ISBN-13(EAN): 9783642072260
Издательство: Springer
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Цена: 52967 р.
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Описание: This is the first book to give a full overview on genome integrity in different species. From microorganisms to humans, this volume provides an interdisciplinary overview of how genome integrity is maintained. Written by an international panel of experts, the book addresses the connection between genome integrity and human disease.

Автор: DePamphilis M.L.., Bell S.D.
Название: Genome duplication
ISBN: 0415442060 ISBN-13(EAN): 9780415442060
Издательство: Taylor&Francis
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Цена: 12341 р.
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Описание: Using model organisms from the three domains of life (Bacteria, Archaea, and Eukarya), this title explains the principle molecular mechanisms of DNA replication and shows how the process is linked to cell division. It is suitable for undergraduate and graduate students.

Автор: Dan Graur
Название: Molecular and Genome Evolution
ISBN: 1605354694 ISBN-13(EAN): 9781605354699
Издательство: Oxford Academ
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Цена: 34530 р.
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Описание: This book describes the driving forces behind the evolutionary process at the molecular and genome levels, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes.

Автор: Dirk-Henner Lankenau; Jean-Nicolas Volff
Название: Transposons and the Dynamic Genome
ISBN: 3642020046 ISBN-13(EAN): 9783642020049
Издательство: Springer
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Цена: 26122 р.
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Описание: Transposable elements and their kind make up the bulk of genomic DNA, approaching 50 percent of the genome. By contrast, the classic genes represent as little as 1.8 percent of genomic DNA, in case of the human genome. This book gives an overview on mobile DNA and how such contradiction to the obligatory stability of genomes can be understood.