Targeted Genome Editing Using Site-Specific Nucleases, Yamamoto, Takashi
Автор: Turksen Название: Genome Editing ISBN: 3319341464 ISBN-13(EAN): 9783319341460 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in mouse zygotes, and generation of reporter stem cells; the text contextualizes these methods in treatment of cardiovascular disease, diabetes mellitus, retinitis pigmentosa, and others. The final chapters round out the book with a discussion of controversies and future directions.
Genome Editing is an essential, of-the-moment contribution to this rapidly growing field. Drawing from a wealth of international perspectives, it presents novel techniques and applications for the engineering of the human genome. This book is essential reading for all clinicians and researchers in stem cells, regenerative medicine, genomics, biochemical and biomedical engineering- especially those interested in learning more about genome editing and applying it in a targeted, specific way.
Автор: Nasheuer Название: Genome Stability and Human Diseases ISBN: 9400731256 ISBN-13(EAN): 9789400731257 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive overview discusses cancer cell biology in relation to Genome stability and Cell cycle regulation. Chapters are devoted to genome stability and anti-cancer drug targets, chromatin factors, DNA repair, apoptosis and other key areas of research.
Автор: Nasheuer Название: Genome Stability and Human Diseases ISBN: 9048134706 ISBN-13(EAN): 9789048134700 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive overview discusses cancer cell biology in relation to Genome stability and Cell cycle regulation. Chapters are devoted to genome stability and anti-cancer drug targets, chromatin factors, DNA repair, apoptosis and other key areas of research.
Автор: Mathilde Causse; Jim Giovannoni; Mondher Bouzayen; Название: The Tomato Genome ISBN: 3662533871 ISBN-13(EAN): 9783662533871 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes the strategy used for sequencing, assembling and annotating the tomato genome and presents the main characteristics of this sequence with a special focus on repeated sequences and the ancestral polyploidy events. It also includes the chloroplast and mitochondrial genomes. Tomato (Solanum lycopersicum) is a major crop plant as well as a model for fruit development, and the availability of the genome sequence has completely changed the paradigm of the species’ genetics and genomics. The book describes the numerous genetic and genomic resources available, the identified genes and quantitative trait locus (QTL) identified, as well as the strong synteny across Solanaceae species. Lastly, it discusses the consequences of the availability of a high-quality genome sequence of the cultivated species for the research community. It is a valuable resource for students and researchers interested in the genetics and genomics of tomato and Solanaceae.
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