Название: WHO Classification of Tumours Pathology & Genetics of Tumours of the Soft Tissue & Bone ISBN: 9283224132 ISBN-13(EAN): 9789283224136 Издательство: WHO Press Рейтинг: Цена: 8000.00 р. Наличие на складе: Есть (4 шт.) Описание: This book is an authoritative, concise reference, prepared by 147 authors from 28 countries. It contains more than 800 colour photographs, numerous MRIs,
ultrasound images, CT scans, charts and approximately 2000 references. Diagnostic criteria, pathological features and associated genetic alterations are described in a strictly
disease-oriented manner.
Sections on all recognized neoplasms and their variants include new ICD-O codes, incidence, age and sex dis
ribution, location, clinical signs and symptoms, pathology, genetics and predictive factors.
Автор: Giese Matthias Название: Molecular Vaccines ISBN: 3709114187 ISBN-13(EAN): 9783709114186 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This up-to-date review of molecular vaccines has authoritative guidance on each stage of vaccine development, from the bench to the pharmacy cabinet. It covers all the relevant scientific principles and introduces innovative research in oncology and elsewhere.
Описание: In Cellular Cardiomyoplasty: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to study cellular cardiomyoplasty, only adult stem cells or adult progenitor cells are included.
Автор: Giese Matthias Название: Molecular Vaccines ISBN: 331900977X ISBN-13(EAN): 9783319009773 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines all aspects of global molecular vaccine research and development. It describes the development of new vaccines from bench to preclinical to clinical studies and launch to the market under EMA and FDA guidelines.
Автор: D. Hunter Best; Jeffrey J. Swensen Название: Molecular Genetics and Personalized Medicine ISBN: 1627039236 ISBN-13(EAN): 9781627039239 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews developments in molecular genetics, showing how they have been adopted in clinical practice. The authors simplify complex genetic concepts and focus on patient related issues. The aim is to help shorten the time from lab bench to bedside.
Автор: Carol A. Wise; Jonathan J. Rios Название: Molecular Genetics of Pediatric Orthopaedic Disorders ISBN: 1493921681 ISBN-13(EAN): 9781493921683 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the past two decades we have seen a surge forward in understanding the genetics and biochemistry underlying many pediatric orthopaedic disorders. A few projects have even progressed into the realm of clinical trials that are primarily aimed at controlling progressive disease. Meanwhile, genomic technology development has outpaced expectations and is enabling gene discovery for disorders that were previously intractable with traditional genetic methods. Included in this latter category are common disorders that display multigenic inheritance, sporadic disorders, and very rare conditions that are difficult to ascertain. Simultaneously, the study of pediatric orthopaedic disorders has been continuously refined and updated, highlighting a number of likely genetic conditions that are as yet unsolved. Molecular Genetics of Pediatric Orthopaedic Disorders updates researchers and clinicians of new developments of pediatric orthopaedic genetics. The chapters inform the audience on the revolution in new genomic methods and the impact this is having on potential study designs and the potential to discover genetic causes of many unsolved orthopaedic conditions. Recent examples have been included of pediatric orthopaedic conditions, both rare and common, that are being solved with these new methods. The book also educates pediatric orthopedic clinicians and geneticists on our understanding of the biology of “classic” genetic diseases that were derived from prior genetic studies. Chapters include biobanks and strategies for studying very rare disorders, genes and pathways causing primordial dwarfism, and notch signaling in congenital scoliosis, and more.
Автор: Jen-Tsan Ashley Chi Название: Molecular Genetics of Dysregulated pH Homeostasis ISBN: 1493916823 ISBN-13(EAN): 9781493916825 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Most biological reactions and functions occur within a narrow range of pH. Any changes in the pH have great impacts on the biological functional at every level, including protein folding, enzymatic activities and proliferation and cell death. Therefore, maintain the pH homeostasis at the local or systemic level is one of the highest priorities for all multicellular organisms. Many redundant mechanisms are in place to maintain the pH homeostasis, a topic that is well covered in the scientific literature and medical textbooks. However, when the pH homeostasis is disrupted in various physiological adaptations and pathological situations, resulting acidity may trigger significant pathophysiological events and modulate disease outcomes. Therefore, understanding how various cells sense and react to acidity have broad impact in a wide variety of human diseases, including cancer, stroke, myocardial infarction and diabetes, renal and infectious diseases. In this book, many investigators have summarized the molecular genetics on the detailed mechanisms by which different mammalian cells sense and response acidity. These chapters cover the acidity with broad impact in biological understanding and human diseases and review various sensing mechanism and cellular responses to pH alterations in both physiological (taste, pain) and pathological settings (ischemia and cancers). Furthermore, these authors present a broad spectrum of investigative approaches to cellular response to acidosis in a in wide variety of human diseases.
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