Modeling Peptide-Protein Interactions : Methods and Protocols, Schueler-Furman, Ora;London, Nir
Автор: Chris Van Der Walle Название: Peptide and Protein Delivery, ISBN: 0123849357 ISBN-13(EAN): 9780123849359 Издательство: Elsevier Science Рейтинг: Цена: 20379.00 р. Наличие на складе: Поставка под заказ.
Описание: The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. This title addresses the routes for delivery of therapeutics. It covers cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery.
Описание: This thesis focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of “affinity guided covalent conjugation.” This newly established methodology provides complementary resolution to protein labeling, imaging and trafficking. By systematically investigating the coordination interaction between protein and quantum dots using various engineered protein ligands, this thesis proposes a general rule for protein self-assembly on the surface of quantum dots and reports a revolutionized nanobelt protein in accordance with this rule. It is an extraordinary example of interdisciplinary research, providing answers to real-life biological problems from a chemistry perspective.
Описание: The Synthesis of biopolymers and their conjugates is of ever increasing importance in bioorganic chemistry and chemical biology. As the need for such systems becomes ever more widespread, their synthesis is necessarily practiced in a broader spectrum of laboratories beyond the specialized ones that have traditionally concentrated in the area.
Автор: Fields Gregg B. Название: Peptide Characterization and Application Protocols ISBN: 1588295508 ISBN-13(EAN): 9781588295507 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Peptide Characterization and Application Protocols is dedicated entirely to the characterization of peptides and their applications for the study of biochemical systems and the contributing authors are all leaders in the field of peptide research. Part I, Characterization, presents the most recent advances in select analytical techniques, including high-performance liquid chromatography (HPLC) for purification and evaluation of peptides and mass spectrometry (MS) for the analysis of standard and modified peptides. Innovative methods of synthesis and characterization of membrane peptides are also presented. Part II, Application, presents a variety of specific applications for synthetic peptides. The collected protocols demonstrate the systematic manner in which peptides can be constructed, analyzed, and applied to attack contemporary problems in biochemistry, and this book will be an indispensable aid in the pursuit of new directions in peptide research.
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