Описание: This book provides a complete guide on tools and techniques for modeling of supercritical and subcritical fluid extraction (SSFE) processes and phenomena. It provides details for SSFE from managing the experiments to modeling and optimization. It includes the fundamentals of SSFE as well as the necessary experimental techniques to validate the models. The optimization section includes the use of process simulators, conventional optimization techniques and state-of-the-art genetic algorithm methods. Numerous practical examples and case studies on the application of the modeling and optimization techniques on the SSFE processes are also provided. Detailed thermodynamic modeling with and without co-solvent and non equilibrium system modeling is another feature of the book.
The book consists of seven chapters. Chapter 1 presents an overview of the field of supercritical and subcritical fluid extraction (SSFE) and their importance to food, cosmetic and pharmaceutical industries. Chapter 2 describes the concepts and methodologies for modeling, simulation as well as optimization. It presents conservation laws related to SFE traditional first principle modeling and optimization techniques, statistical modeling as well as advanced artificial intelligence (AI) techniques like genetic algorithm, fuzzy logic and artificial neural network (ANN). The characteristics and physical properties of palm oil as the most referred solute in the book, and descriptions of some existing palm oil industrial processes are presented in Chapter 3. In Chapter 4, the first principle methodology is applied for modeling of properties of palm oil components, mixtures and for the supercritical fluid extraction of palm oil components. Modeling applications involving advanced techniques such as AI, ANN and fuzzy logics and ANFIS are discussed in Chapter 5. Next, Chapter 6 describes experimental design concepts and procedures as well as statistical optimization techniques involving SSFE processes. Finally, optimisation of SSFE using first principle modeling and other advanced techniques are presented in Chapter 7.
Enzymes are currently used in various industries, most commonly in food, detergents, and pharmaceuticals production. Lipases are hydrolytic enzymes that demonstrate great potential as an alternative to conventional catalysts in a number of industrial applications. A complete understanding of enzymes, and their proteins structure and environmental behavior, can greatly aid in the further development of industrial applications. Supercritical Fluids Technology in Lipase Catalized Processes provides basic information about enzymes, their sources, reaction kinetics, and main industrial applications. The book focuses in lipases. their main sources, structure, and features, with an emphasis on their specificity and interfacial activity, and presents proven techniques for isolating, extracting, and purifying.
Comprised of six compact chapters, this comprehensive guide introduces:
Immobilization techniques and immobilized lipases that allow repeated use (which is essential from an economic point of view)
Different bioreactor configurations using immobilized lipases
The latest information on the available technologies in lipolytic reactions
The advantages of nonaqueous media in biochemical synthesis over aqueous and solvent-free systems
Material on the use of lipases in nonaqueous media to overcome the drawbacks usually encountered with the use of conventional chemical catalysts
The use of supercritical fluids (SCFs) as a green alternative reaction medium
Factors affecting the physical properties of lipases in this medium and, hence, their activity and stability
A case study using supercritical carbon dioxide (SC-CO2) for biodiesel production
Novel, cutting-edge technology, using immobilized enzymes to reduce the overall production cost
Supercritical Fluids Technology in Lipase Catalized Processes outlines the main industrial applications of common enzymes and discusses relevant challenges and innovations emerging in the field.
Автор: Yashwant Pathak; Vijaykumar Sutariya; Anjali A. Hi Название: Nano-Biomaterials For Ophthalmic Drug Delivery ISBN: 3319293443 ISBN-13(EAN): 9783319293448 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This consolidated reference book addresses the various aspects of nano biomaterials used in ophthalmic drug delivery, including their characterization, interactions with ophthalmic system and applications in treatments of the ophthalmic diseases and disorders. In the last decade, a significant growth in polymer sciences, nanotechnology and biotechnology has resulted in the development of new nano- and bioengineered nano-bio-materials. These are extensively explored as drug delivery carriers as well as for implantable devices and scaffolds. At the interface between nanomaterials and biological systems, the organic and synthetic worlds merge into a new science concerned with the safe use of nanotechnology and nano material design for biological applications. For this field to evolve, there is a need to understand the dynamic forces and molecular components that shape these interactions. While it is impossible to describe with certainty all the bio physicochemical interactions at play at the interface, we are at a point where the pockets of assembled knowledge are providing a conceptual framework to guide this exploration, and review the impact on future product development. The book is intended as a valuable resource for academics and pharmaceutical scientists working in the field of polymers, polymers materials for drug delivery, drug delivery systems and ophthalmic drug delivery systems, in addition to medical and health care professionals in these areas.
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