Analysis of Pharmaceuticals by Capillary Electrophoresis, Kevin D. Altria; Kevin D. Altria

Автор: Wim Kok
Название: Capillary Electrophoresis: Instrumentation and Operation
ISBN: 3322831353 ISBN-13(EAN): 9783322831354
Издательство: Springer
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Описание: Die Kapillarelektrophorese kann als routinemд ige Analysenmethode in der Praxis eingesetzt werden. Der Autor dieser englischsprachigen Monographie beschreibt alle technischen und praktischen Aspekte, die dabei berьcksichtigt werden mьssen. Aber er geht auch auf neue wissenschaftliche Entwicklungen ein, die noch erforscht werden und sich bis jetzt nicht fьr die Routine eignen. Das Buch spricht - im Gegensatz zu dem Titel von Engelhardt - fortgeschrittenere Leser an.

Автор: Christoph Heller; Kevin D. Altria
Название: Analysis of Nucleic Acids by Capillary Electrophoresis
ISBN: 3322910172 ISBN-13(EAN): 9783322910172
Издательство: Springer
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Описание: During the last decade, capillary electrophoresis has been developed into a very powerful analytical technique, which has many advantages over conventional slab gel techniques. The improvement is comparable to the one occuring earlier in the field of chromatography, with the introduction of the high performance technology. How important this technique has be- come, is reflected by the shear volume of papers published each month; as well as a dozen of books already published on this subject. One of the most important conferences in the field, the "International Symposium on High Performance Capillary Electrophoresis" attracts now nearly thousand people every year. As capillary electrophoresis can be applied to many different analytical problems, a spe- cialization is unavoidable. This evolution is also reflected in the development of instrumen- tation: whereas the first devices were designed for all possible applications, new instruments are now built, that are specialized for one particular task, e.g. DNA analysis. I very much welcome the decision of the series editor and the publisher, to edit a series ofspecialized books, covering all aspects of capillary electrophoresis. Having worked on the electrophoretic separation of DNA for many years, I am convinced that there are so many different aspects on this issue that they deserve a whole book on their own. Therefore, I was happy to agree when being asked to edit this book.

Автор: Kevin D. Altria; Aran Paulus; Antje Klockow-Beck
Название: Analysis of Carbohydrates by Capillary Electrophoresis
ISBN: 3322850226 ISBN-13(EAN): 9783322850225
Издательство: Springer
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Описание: Carbohydrates are ubiquitous. They come as monomers, oligomers and polymers with a startling variety of chemical, physical and material properties. They affect almost every as- pect of human live. For example they are an essential part of our nutrition. Cellulose, a car- bohydrate polymer, acts as a central material in civilization: as building material for housing and as paper for written communication. Scientifically, the interest in carbohydrates ranges from structural elucidation of simple carbohydrates to fundamental biochemical processes such as photosynthesis and glycolysis. Always, a deeper understanding of a particular aspect of carbohydrate chemistry was accompanied by new methods of measuring and characteri- zing this class of molecules. During the last decades a better understanding of the roles of carbohydrates in biochemi- cal pathways developed. It turned out, that carbohydrates attached to proteins in glycoprote- ins are involved in a number of molecular recognition and targeting processes. This lead to a new research field: Glycobiology. However, unlike for proteins or nucleic acids, there is at this time no consistent theory how chemical composition and structure controls function and inherent information. In order to develop the database, on which new theories and scientific hypothesis are founded, analytical methods to separate compounds with an enormous struc- tural diversity and only minor differences in chemical or physical properties has to be deve- loped, preferably using only minute quantities.