Автор: Fu Haian Название: Protein-Protein Interactions / Methods and Applications ISBN: 1588291200 ISBN-13(EAN): 9781588291202 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A collection of highly successful biochemical, biophysical, genetic, and computational techniques for studying protein-protein interactions. These readily reproducible methods demonstrate how to identify protein interaction partners, qualitatively or quantitatively measure protein-protein interactions in vitro or in vivo, monitor protein-protein interactions as they occur in living cells, and determine interaction interfaces. The techniques described utilize a variety of cutting-edge technologies, including surface plasmon resonance (SRP), fluorescence resonance energy transfer (FRET), fluorescence polarization (FP), isothermal titration calorimetry (ITC), circular dichroism (CD), protein fragment complementation assays (PCA), various two-hybrid systems, and proteomics and bioinformatics-based approaches, such as the Scansite program for computational analysis. These powerful tools are essential for deciphering how proteins interact with each other to form biological networks, as well as for unraveling protein-protein interactions in disease to find novel therapeutic targets.
Автор: Schueler-Furman, Ora;London, Nir Название: Modeling Peptide-Protein Interactions : Methods and Protocols ISBN: 1493967967 ISBN-13(EAN): 9781493967964 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume covers an array of techniques available for studying peptide-protein docking and design.
Автор: Mark A. Williams; Tina Daviter Название: Protein-Ligand Interactions ISBN: 1493958739 ISBN-13(EAN): 9781493958733 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In its revised 2nd Edition, this Methods in Molecular Biology (TM) book provides a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins. Offers materials lists, reproducible protocols, notes and more.
Автор: John W. Shriver Название: Protein Structure, Stability, and Interactions ISBN: 1617378550 ISBN-13(EAN): 9781617378553 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Supporting and up-dating previous volumes, this text focuses on theory and practical applications for both established methods and new procedures. The volume presents an overview of many techniques currently used to study protein stability and interactions.
Автор: Michael D. Wendt Название: Protein-Protein Interactions ISBN: 3642439551 ISBN-13(EAN): 9783642439551 Издательство: Springer Рейтинг: Цена: 39182.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Protein-Protein Interactions as Drug Targets.- Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics.- The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer.- Protein-Protein Interaction Targets to Inhibit HIV-1 Infection.- Inhibitors of Protein-Protein Interactions in Paramyxovirus Fusion - a Focus on Respiratory Syncytial Virus.- Rational Design Strategies for Developing Synthetic Inhibitors of Helical Protein Interfaces.- The Discovery of Navitoclax, a Bcl-2 Family Inhibitor.
Автор: Rainer Jaenicke; E. Helmreich Название: Protein-Protein Interactions ISBN: 3642654584 ISBN-13(EAN): 9783642654589 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The present volume contains the proceedings of the 23rd Mos- bach Colloquium on "Protein-Protein Interactions." It includes the paper by Prof. S. LIFSON who unfortunately was unable to attend. Discussions were included whenever possible in order to make the complete proceedings accessible to the future reader. The colloquium was generously supported by the firms who are corporate members of the Gesellschaft fur Biologische Chemie. Dr. W. B. GRATZER and Dr. L. JAENICKE, as weIl as some of the invited speakers, were a tremendous help in preparing the program and we wish to thank them for their helpfuI suggestions and advice. Our appreciation extends to Prof. E. AUHAGEN and Prof. H. GIBIAN, and their secretaries, who shared the burden of organizing the colloquium. In addition, we wish to express our gratitude to Springer-Ver- Iag, and especially to Dr. H. MAYER-KAUPP for editoriaI help and for the rapid publication of this volume. We hope that the reader, Iike the audience in the Mosbach market hall, will gain an impression of the present state of protein research and of the way in which intermolecular interactions hold specific implications for the structure and function of proteins. Regensburg and Wurzburg, autumn 1972 R. JAENICKE E. HELMREICH Contents Introduction. R. JAENICKE (Regensburg) 1 Molecular Forees. S. LIFSON (Rehovot) ................... 3 Structure, Function and Dynamics of a ReguIatory Enzyme: Aspartate Transcarbamylase. H. K. SCHACHMAN (Berkeley) 17 Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 . . . . . . . . . . . . . .
Автор: G. Weber Название: Protein Interactions ISBN: 0412030314 ISBN-13(EAN): 9780412030314 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presents an examination of the physical properties of proteins and their associations with solvents, ligands, and each other. This book offers an overview of basic thermodynamic principles and describes the covalent and noncovalent binding of single and multiple ligands and their effects on protein-protein associations.
Автор: Mark A. Williams; Tina Daviter Название: Protein-Ligand Interactions ISBN: 1627033971 ISBN-13(EAN): 9781627033978 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In its revised 2nd Edition, this Methods in Molecular Biology (TM) book provides a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins. Offers materials lists, reproducible protocols, notes and more.
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