Oxidation and inflammation, a molecular link between non-communicable diseases.- Oxidative stress and DNA damage in obesity-related tumorigenesis.- High density lipoproteins and ischemia reperfusion injury: The therapeutic potential of HDL to modulate cell survival pathways.- The DING family of phosphate binding proteins in inflammatory diseases.- Inflammation, infection, cancer and all that...The role of paraoxonases.- Autophagy is an inflammation-related defensive mechanism against disease.- Delta-5 and Delta-6 Desaturases: crucial enzymes in polyunsaturated fatty acid-related pathways with pleiotropic influences in health and disease.- Systemic inflammation, intestine and paraoxonase-1.- Serotonin modulation of macrophage polarization: inflammation and beyond.- Energy metabolism and metabolic sensors in stem cells: The metabostem crossroads of aging and cancer.- Molecular promiscuity of plant polyphenols in the management of age-related diseases: far beyond their antioxidant properties.- Postprandial Inflammation: Targeting glucose and lipids.- Dynamic interplay between metabolic syndrome and immunity.- The axis AGE-RAGE-soluble RAGE and oxidative stress in chronic kidney disease.- The chemokine (C-C motif) ligand 2 in neuroinflammation and neurodegeneration.
Автор: Lane Название: Central Nervous System Diseases and Inflammation ISBN: 0387738932 ISBN-13(EAN): 9780387738932 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Focusing on inflammatory CNS disease, this book explores how chemokines affect disease. It contains four sections which revolve around areas of interest within the field of neuroimmunology, virology, pharmacology and disease.
Автор: Steven M. Dubinett Название: Inflammation and Lung Cancer ISBN: 149392723X ISBN-13(EAN): 9781493927234 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In recent years there have been various discoveries connecting inflammation and lung cancer and clearly there is growing interest in this area of cancer research. The link between unresolved inflammation and cancer has been well established with estimates that 15% of cancer deaths are inflammation?related. Evidence for this link includes the following: a) some inflammatory diseases are associated with increased risk of cancer development; b) inflammatory mediators are present surrounding and within most tumors; c) overexpression of inflammatory cytokines increases cancer development and progression in murine studies; d) inhibition of inflammatory mediators decreases cancer development and progression; and e) the use of non?steroidal anti?inflammatory drugs (NSAIDs) has been found to decrease cancer incidence and delay progression. The volume will present aspects of the inflammatory tumor microenvironment (TME), its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of micro?RNAs (miRNAs) and an increase in a stem cell phenotype. The book will also cover the mechanisms of inflammatory mediators. Chronic overexpression of inflammatory mediators in the TME, as seen in smokers and patients with non?small cell lung cancer (NSCLC), can also lead to increased tumor initiation, progression, invasion and metastasis. The volume will provide a comprehensive perspective of the latest findings and summaries of progress made regarding inflammation and its connection to lung cancer.
Автор: Bharat B. Aggarwal; Bokyung Sung; Subash Chandra G Название: Inflammation and Cancer ISBN: 3034808364 ISBN-13(EAN): 9783034808361 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
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