Автор: Serguei V. Kozlov (Ed.) Название: Inflammation and Cancer ISBN: 1603275290 ISBN-13(EAN): 9781603275293 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Addresses various aspects of experimental cancer biology, focused on inflammation-mediated tumorigenesis, while promoting improvisations on a per-case basis. This title describes experimental strategies aimed at investigating the molecular cross-talks between components of cell signaling chains and their ramifications in diagnostic development.
Описание: This volume represents a collection of contributions from the 6th International Conference on Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Related Diseases held in Boston from September 12-15, 1999.
Автор: Bharat B. Aggarwal; Bokyung Sung; Subash Chandra G Название: Inflammation and Cancer ISBN: 3034808364 ISBN-13(EAN): 9783034808361 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Автор: Angus G. Dalgleish; Burkhard Haefner Название: The Link Between Inflammation and Cancer ISBN: 1441938818 ISBN-13(EAN): 9781441938817 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Inflammation and Cancer.- Chronic Inflammation and Pathogenesis of GI and Pancreatic Cancers.- Cytokines, NF-?B, Microenvironment, Intestinal Inflammation and Cancer.- Regulation if NF-?B Transcriptional Activity.- The Role of Immune Cells in the Tumor Microenvironment.- Tumor-Microenvironment Interactions.- CD95L/FasL and TRAIL in Tumour Surveillance and Cancer Therapy.- Infection & Neoplastic Growth 101.- Cytokines as Mediators and Targets for Cancer Cachexia.- Targeting NF-?B in Anticancer Adjunctive Chemotherapy.
Автор: Andrew J. Dannenberg; Nathan A. Berger Название: Obesity, Inflammation and Cancer ISBN: 1461468183 ISBN-13(EAN): 9781461468189 Издательство: Springer Рейтинг: Цена: 30039.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Offering cutting edge research on inflammation, obesity and carcinogenesis, this book covers obesity and insulin resistance, changes in chromatin structure, interactions between adipocytes and macrophages and links of dietary fat to inflammation and cancer.
Описание: Inflammation and cancer are two major disorders that cause huge concerns in our society. However, what one may not know is that both diseases are closely associated and, in particular, both occur in the gastrointestinal tract and liver. This book describes the mechanics of how inflammation can progress to cancer in these organs.
Автор: C. Gasche; M. Gassull; J.M. Herrer?as Guti?rrez; E Название: Intestinal Inflammation and Colorectal Cancer ISBN: 1402068255 ISBN-13(EAN): 9781402068256 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Falk Symposium 158 held in Seville, Spain, March 23-24 2007
Автор: Kozlov Название: Inflammation and Cancer ISBN: 1617379239 ISBN-13(EAN): 9781617379239 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, expert researchers deliver a systematic guide to techniques addressing various aspects of experimental cancer biology. The book selectively focuses on inflammation-mediated tumorigenesis, while promoting improvisations on a per-case basis.
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 10 offer a valuable guide to both cellular processes, while encouraging researchers to explore their potentially important connections. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis.
This is the tenth volume of the multivolume series that discusses, in detail, almost all aspects of the autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. Volume 10 of the Autophagy series discusses the role of a novel binuclear palladacycle complex that inhibits melanoma growth through apoptosis and autophagy.
Presents the most advanced information regarding the role of the autophagic system in life and death
Contains a direct focus on the role of a novel binuclear palladacycle complex that inhibits melanoma growth
Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation
States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities
Edited work with chapters authored by leaders in the field from around the globe--the broadest, most expert coverage available
Автор: Kozlov Название: Inflammation and Cancer ISBN: 1617379050 ISBN-13(EAN): 9781617379055 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: One out of seven newly diagnosed malignancies worldwide result from infection and chronic inflammation in conjunction with cancer. This book is a guide for fighting the 2,200 inflammation-related oncogenesis fatalities that occur every day.
Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to both cellular processes while inciting researchers to explore their potentially important connections. "Volume 8 Autophagy and Human Diseases," concentrates on the role of Autophagy in human diseases, including tumorigenesis. The diseases discussed include melanoma, liver cancer, pancreatic cancer, and neurodegenerative disorders. Loss of autophagy in the central nervous system causes neurodegeneration (Alzheimers disease, Huntington s disease, Parkin s disease, and Amyotrophic Lateral Sclerosis). Melanoma is one of the most serious diseases in humans. Autophagy plays a key role in the anticancer response to Chemotherapy. However, autophagy can increase or decrease the effectiveness of chemotherapy. The reasons for these contradictory effects are explained. Autophagy also plays a role in idiopathic inflammatory diseases, infection, and immunity. An explanation is given how autophagy is closely linked to control of innate and adaptive immune responses in host defense in part by regulating cytokine production. The role of autophagy in cutaneous malignant melanoma is discussed in detail and expression of Beclin 1 and LC3 autophagic genes in melanoma is included to explain the molecular mechanisms underlying this very serious disease, which tends to metastasize to the brain. The effect of the treatment of this disease using Terfenadine through the induction of autophagy and apoptosis is also included. Autophagy and apoptosis are two main mechanisms involved in programmed cell death.
Considering that autophagy is associated with numerous biological processes including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer s, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases, there is a great need to understanding its role. Cell homeostasis is achieved by balancing biosynthesis and cellular turnover. In spite of the increasing importance of autophagy in various pathophysiological situations (conditions) mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases (e.g., autoimmune disease) remains poorly understood.
Volumes in the Series
Volume 1: Molecular Mechanisms. Elucidates autophagy s association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer s, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn s Disease, Gaucher Disease, Huntington s Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis. Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and exec
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