Cellular Function and Metabolism, Yoshio Yazaki; Seibu Mochizuki
Автор: Khalil Ahmed; Olaf-Georg Issinger; Ryszard Szyszka Название: Protein Kinase CK2 Cellular Function in Normal and Disease States ISBN: 3319145436 ISBN-13(EAN): 9783319145433 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Protein kinase CK2 (formerly casein kinase II or 2) is known to play a critical role in the control of cell growth and cell death and is thus intimately involved in the development of cancer. More specifically, CK2 has been found to be elevated in all cancers examined. While CK2 levels are known to be high in proliferating normal cells, CK2 has also been found to be a potent suppressor of apoptosis and is a link to the cancer cell phenotype, which is characterized by deregulation of both cell proliferation and cell death. Indeed, it would appear that CK2 impacts many of the hallmarks of cancer and it has now gained considerable attention as a potential target for cancer therapy. Protein Kinase CK2 and Cellular Function in Normal and Disease States increases knowledge of the role of CK2 in the development of cellular dysfunction and emphasizes that this protein may serve as a target of drug development for improved cancer therapy. In addition, it is a handy tool that provides cancer researchers, graduate students, and all scientists involved in CK2 research with one main source for the latest advances in CK2 research.
Автор: Marks, Friedrich Muller-decker, Karin Klingmuller, Название: Cellular signal processing ISBN: 0815342152 ISBN-13(EAN): 9780815342151 Издательство: Taylor&Francis Рейтинг: Цена: 7656.00 р. Наличие на складе: Поставка под заказ.
Описание: Offers a view of cell signaling that is based on the concept of protein interactions acting as sophisticated data processing networks that govern intracellular and extracellular communication. This title covers important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling.
From the Lab to Clinical Settings--Advances in Quantitative, Noninvasive Optical Diagnostics
Noninvasive fluorescence imaging techniques, novel fluorescent labels, and natural biomarkers are revolutionizing our knowledge of cellular processes, signaling and metabolic pathways, the underlying mechanisms for health problems, and the identification of new therapeutic targets for drug discoveries. Natural Biomarkers for Cellular Metabolism: Biology, Techniques, and Applications delves into the current state of knowledge on intrinsic fluorescent biomarkers and highlights recent developments in using these biomarkers for the metabolic mapping and clinical diagnosis of healthy and diseased cells and tissues.
Autofluorescent Biomarkers for Biomedical Diagnostics
The book's first section introduces the fundamentals of cellular energy metabolism as well as natural biomarkers within the context of their biological functions. The second section outlines the theoretical and technical background of quantitative, noninvasive, autofluorescence microscopy and spectroscopy methods, including experimental design, calibration, pitfalls, and remedies of data acquisition and analysis. The last two sections highlight advances in biomedical and biochemical applications, such as monitoring stem cell differentiation in engineered tissues and diagnosing cancer and ophthalmic diseases quantitatively and noninvasively.
Tailored to Interdisciplinary Researchers
Covering cell biology, imaging techniques, and clinical diagnostics, this book provides readers with a complete guide to studying cellular/tissue metabolism under healthy, diseased, and environment-induced stress conditions using natural biomarkers. The book is designed for graduate and advanced undergraduate students, biophysics instructors, medical researchers, and those in pharmaceutical R&D.
Автор: James Bassingthwaighte; Carl A. Goresky; John H. L Название: Whole Organ Approaches to Cellular Metabolism ISBN: 1461274494 ISBN-13(EAN): 9781461274490 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Today, research priorities have turned more to cell-cell interactions, toward understanding the utility of the gap junctional connections between endothelial cells and neighboring smooth muscle cells, neuronal twigs, and the parenchymal cells of organs.
Автор: Brehon Laurent Название: Chromatin Dynamics in Cellular Function ISBN: 3642070248 ISBN-13(EAN): 9783642070242 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume includes timely reviews of several aspects of chromatin biology written by scientists at the forefront of this rapidly moving field. Topics covered include the structure and function of protein modules within chromatin-remodeling proteins, newly characterized histone modifications (methylation, ubiquitylation) and their functional consequences, transcription and histone dynamics, roles of chromatin remodeling factors in DNA replication and repair, and current models of nucleosome-remodeling mechanisms.
Описание: Peroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism.
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