Khalil Ahmed; Olaf-Georg Issinger; Ryszard Szyszka Protein Kinase CK2 Cellular Function in Normal and Disease States 9783319145433

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Автор: Khalil Ahmed; Olaf-Georg Issinger; Ryszard Szyszka
Название: Protein Kinase CK2 Cellular Function in Normal and Disease States
ISBN: 9783319145433
Издательство: Springer
Классификация:

Онкология

Биохимия

Белки

Клеточная биология (цитология)

ISBN-10: 3319145436
Обложка/Формат: Hardcover
Страницы: 378
Вес: 0.82 кг.
Дата издания: 25.03.2015
Серия: Advances in Biochemistry in Health and Disease
Язык: English
Издание: 2015 ed.
Иллюстрации: 17 tables, black and white; 60 illustrations, color; 31 illustrations, black and white; xxiii, 378 p. 91 illus., 60 illus. in color.
Размер: 234 x 156 x 24
Читательская аудитория: Professional & vocational
Основная тема: Cancer Research
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: Protein kinase CK2 (formerly casein kinase II or 2) is known to play a critical role in the control of cell growth and cell death and is thus intimately involved in the development of cancer. More specifically, CK2 has been found to be elevated in all cancers examined. While CK2 levels are known to be high in proliferating normal cells, CK2 has also been found to be a potent suppressor of apoptosis and is a link to the cancer cell phenotype, which is characterized by deregulation of both cell proliferation and cell death. Indeed, it would appear that CK2 impacts many of the hallmarks of cancer and it has now gained considerable attention as a potential target for cancer therapy. Protein Kinase CK2 and Cellular Function in Normal and Disease States increases knowledge of the role of CK2 in the development of cellular dysfunction and emphasizes that this protein may serve as a target of drug development for improved cancer therapy. In addition, it is a handy tool that provides cancer researchers, graduate students, and all scientists involved in CK2 research with one main source for the latest advances in CK2 research.
Дополнительное описание: 1. CK2 Suppression of Apoptosis.- 2. Structural Determinants of CK2 Regulation.- 3. Targeting Protein Kinase: CK2 Suppresses Pro-Survival Signaling Pathways and Growth of Gliobastoma.- 4. The Roles of CK2 in Drosophila Neurogenesis.- 5. Targeting the CK2

Protein Kinase CK2 Cellular Function in Normal and Disease States, Khalil Ahmed; Olaf-Georg Issinger; Ryszard Szyszka