Описание: The second part focuses on the elucidation of key target proteins that could be exploited for cancer prevention, an the role of phytochemicals in cancer prevention, updates on basic research related to phytochemicals action critical for cancer prevention, and updates on translational knowledge on cancer prevention by phytochemicals.
Автор: Siddik Название: Checkpoint Controls and Targets in Cancer Therapy ISBN: 1617796352 ISBN-13(EAN): 9781617796357 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Checkpoint regulation is critical in understanding cancer development and cancer therapy. This book builds upon existing concepts of checkpoints and aims to expand our understanding of the inner workings of the critical checkpoint machinery.
Автор: Champney W. Scott Название: New Antibiotic Targets ISBN: 1588299155 ISBN-13(EAN): 9781588299154 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. This volume features drug targets including peptide deformylase, ribosome formation, lipopolysaccharide and fatty acid biosynthesis and signal transduction pathways.
Автор: Klaus, von der Helm; Bruce D. Korant; John C. Cher Название: Proteases as Targets for Therapy ISBN: 3642630235 ISBN-13(EAN): 9783642630231 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Chatterjee Название: Molecular Targets and Strategies in Cancer Prevention ISBN: 3319312529 ISBN-13(EAN): 9783319312521 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book focuses on the understanding of molecular pathways by which normal cell progress to the definable stage of cancer. The chapters explore microbiota and chronic inflammation, multiple myeloma chemoprevention, microRNAs, cancer regulation, liquid biopsies, and angiogenesis. Recent advances of molecular risk assessment, tumor microenvironment, microneoplasia, malignant gene expressions are highlighted to provide a means and design of future cancer prevention strategies and challenges thereupon. The volume also explores various receptor drugs that are in development process with the emphasis of inhibitors used to prevent malignant gene expression. The book bridges the gap between basic science and clinical application of current knowledge of cancer and emphasizes that tumor progression and cancer metastasis are not random - treatments and cure are logical and eventual.
Expertly authored and drawing from a wealth of international perspectives, Molecular Targets and Strategies in Cancer Prevention is invaluable reading for clinicians and researchers in the fields of oncology and molecular biology.
This unique book deals with both inflammation and cancer in a single source of publication. They are seldom grouped together although it has been known that both diseases are closely associated, particularly in the gastrointestinal tract and liver. As the book touches on two such major areas of diseases in humans, it should be of interest to a wider audience of researchers and readers. It is noted that the book combines the effort of both basic scientists and clinicians from different countries with extensive experiences in molecular biology and clinical practice to unveil the most updated picture of the pathogenesis and therapeutic strategies in the treatment of inflammation and cancer in the digestive tract. In this regard, potential pathogenic modulators and also therapeutic options are widely discussed. These types of information would definitely broaden our knowledge in better understanding these diseases.
Автор: Susan Napier; Matilda Bingham Название: Transporters as Targets for Drugs ISBN: 3642099696 ISBN-13(EAN): 9783642099694 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In each volume of Transporters as Targets for Drugs an overview chapter introduces the newcomer to the topic covered. The series covers hot topics of frontier research summarized by reputed scientists in the field.
Автор: Timothy G. Geary; Aaron Maule Название: Neuropeptide Systems as Targets for Parasite and Pest Control ISBN: 1489998608 ISBN-13(EAN): 9781489998606 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume presents a comprehensive review of recent research on neuropeptides in arthropods and helminths. Readers will find an overview of the biology of neuropeptidergic function, and an understanding of the molecular biology of the genes that encode precursors and receptors in these organisms.
Автор: Ryan J. Sullivan Название: BRAF Targets in Melanoma ISBN: 1493921428 ISBN-13(EAN): 9781493921423 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume contains a collection of writings from the leaders in the fields of Molecular Biology and Melanoma Research which will begin to tell the ever-expanding story of the most recent findings, discoveries, and potential of BRAF-directed targets in melanoma. Recent research has shown that BRAF inhibitors are effective for a short period of time, but there is little hope that this drugs as single agents will lead to durable benefit in a majority of patients. Among scientists and researchers who work in drug discovery, there is a lot of interest in the development of molecularly targeted cancer agents. Namely, the identification of a molecular target, the selection of molecules which effectively inhibit this target. What is starkly different about the development of this class of compounds, however, is that the mechanism of action of these agents are not as straightforward as was once previously assumed and the mechanisms of resistance that tumor cells employ to evade complete destruction are unlike any that have been described before. These discoveries in addition to utilization of modern molecular biology techniques have led to a series of hypotheses regarding which other types of molecules could be used in combination with BRAF-inhibitors in hopes of revolutionizing the potential of therapeutics in melanoma.
Автор: Ryutaro Utsumi Название: Bacterial Signal Transduction: Networks and Drug Targets ISBN: 1441927034 ISBN-13(EAN): 9781441927033 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This fascinating book encourages many microbiologists and students to enter the new world of signal transduction in microbiology. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been unearthed.
Автор: Iqbal S. Grewal Название: Therapeutic Targets of the TNF Superfamily ISBN: 1441927999 ISBN-13(EAN): 9781441927996 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For two decades, TNF superfamily has been the most investigated area of basic medical research. This book offers a state-of-the-art account of that research, including the role of TNF superfamily members to fight cancer and autoimmune disease.
Автор: Champney Название: New Antibiotic Targets ISBN: 1617378437 ISBN-13(EAN): 9781617378430 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. The book identifies additional novel cellular targets for these new therapies. It will assist in the treatment of infectious diseases.
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