The Molecular Basis of Viral Replication, R. Bercoff
Автор: Merten Название: Viral Vectors for Gene Therapy ISBN: 161779094X ISBN-13(EAN): 9781617790942 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The huge potential for gene therapy to cure a wide range of diseases has led to high expectations and a great increase in research efforts in this area, particularly in the study of delivery via viral vectors, widely considered to be more efficient than DNA transfection. In Viral Vectors for Gene Therapy: Methods and Protocols, experts in the field present a collection of their knowledge and experience featuring methodologies that involve virus production, transferring protocols, and evaluating the efficacy of gene products. While thoroughly covering the most popular viral vector systems of adenovirus, retrovirus, and adeno-associated virus, this detailed volume also explores less common viral vector systems such as baculovirus, herpes virus, and measles virus, the growing interest in which is creating a considerable demand for large scale manufacturing and purification procedures. Written in the highly successful Methods in Molecular Biology™ series format, many chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and vital tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Viral Vectors for Gene Therapy: Methods and Protocols provides basic principles accessible to scientists from a wide variety of backgrounds for the development of gene therapy viral products that are safe and effective.
Описание: The articles in this volume provide a comprehensive overview of our current understanding of the roles played by cellular factors in the early steps of retroviral replication.
Автор: Monika Glinkowska; Lidia Boss; Grzegorz Wegrzyn Название: DNA Replication Control in Microbial Cell Factories ISBN: 3319105329 ISBN-13(EAN): 9783319105321 Издательство: Springer Рейтинг: Цена: 9141.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction.- Coordinating duplication of genetic material with cell growth - current views and old questions.- Structural organization of cellular processes and the regulation of cell cycle.- The link between metabolism and DNA replication.- Transcriptional activation - the unsolved problem.- Activity of DnaA is inhibited by components of translation machinery.- Nucleoid-associated proteins modulate activity of the DnaA initiator.- Interaction of DnaA with acidic components of fluid cellular membrane regulates its nucleotide-bound status and binding to oriC.- Influence of DNA replication on cell structure and function.- Conclusions.
Автор: Laura Kaguni Название: DNA Replication Across Taxa,39 ISBN: 0128047356 ISBN-13(EAN): 9780128047354 Издательство: Elsevier Science Рейтинг: Цена: 18528.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
DNA Replication Across Taxa, the latest volume in The Enzymes series summarizes the most important discoveries associated with DNA replication.
Описание: There are three major types of human retroviruses, namely HIV, HTLV, and endogenous human retroviruses. This book presents the various findings on the replication of these human retroviruses. It is suitable for students, researchers and medical professionals.
Название: Dna replication ISBN: 1493925954 ISBN-13(EAN): 9781493925957 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: DNA Replication
Название: Initiation of dna replication in eukaryotes ISBN: 3319246941 ISBN-13(EAN): 9783319246949 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: ГЇВїВЅ Every time a cell divides, a copy of its genomic DNA has to be faithfully copied to generate new genomic DNA for the daughter cells. The Initiation of DNA Replication in Eukaryotes will focus on how DNA replication is initiated in eukaryotic cells.
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