Cell-Mediated Effects of Immunoglobulins, Wolf H. Fridman
Автор: Lefranc/Lefranc Название: THE IMMUNOGLOBULIN FACTSBOOK ISBN: 012441351X ISBN-13(EAN): 9780124413511 Издательство: Elsevier Science Рейтинг: Цена: 13980.00 р. Наличие на складе: Поставка под заказ.
Описание: This is a reference for all functional and ORF immunoglobulin genes. It includes information on immunoglobulin structural and biological properties, chain synthesis, gene chromosomal localization, organization of the IGH, IGK and IGL loci, and the immunoglobulin heavy, kappa and lambda loci.
Описание: In multicellular organisms, communication between cells involves secretion of proteins that bind to receptors on neighboring cells. While this has been well documented, another mode of intercellular communication has recently become the subject of increasing interest: the release of exosomes. In cancer, tumor exosomes are involved in various aspects of pathogenesis, including proliferation, immunosuppression, and metastasis. Given the ability of exosomes to export unneeded endogenous molecules from cells, these structures hold great potential as anticancer therapeutic agents. They are also being studied as prognostic markers for cancer.
Автор: Zhang Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 1607617684 ISBN-13(EAN): 9781607617686 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.
Описание: This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment. To understand the function of this response in cancer cells, he has provided a systems biology experimental framework to study quantitative and dynamical aspects of autophagy in single cancer cells using live-cell imaging and quantitative fluorescence microscopy. This framework can provide new insights on function of autophagic response in cancer cells.
Автор: Shurin Michael R., Smolkin Yuri S. Название: Immune Mediated Diseases: From Theory to Therapy ISBN: 0387720049 ISBN-13(EAN): 9780387720043 Издательство: Springer Рейтинг: Цена: 36197.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The goal of the International Immune-Mediated Diseases: From Theory to Therapy (IMD) Congress is to bring the best world immunologists and clinicians to Moscow to participate in plenary sessions, symposia and educational workshops designed to expose basic and clinical immunologist as well as practicing clinicians to the newest developments in the field. First IMD Congress consisted of 8 Plenary Sessions, 40 Symposia and 25 Workshops. The meeting attracted almost 2000 participants and speakers from 15 countries. After this great success of the First IMD Congress, the Organizing Committee decided to convene the meeting every other year and the Second International IMD Congress was planned for September 2007. Special attention will be given to innovative therapeutic modalities, allergy and asthma, immunodeficiency, tumor and transplant immunology, immunotherapy and vaccines, HIV and infectious diseases, autoimmune diseases, inflammation, immunomonitoring and immunodiagnostics.This volume includes contributions from the speakers of the Second IMD Congress (September 10-15, 2007; Moscow, Russia) who are eager to share some of the academic and clinical enthusiasm that defines the IMD meetings.
Автор: M. D. Cooper; T. Takai; J.V. Ravetch Название: Activating and Inhibitory Immunoglobulin-like Receptors ISBN: 4431679596 ISBN-13(EAN): 9784431679592 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is the first attempt to summarize and highlight all known aspects of immunoglobulin-like receptors, providing a topical overview of the roles and characteristic features of the immunoglobulin-like receptors and related molecules in the immune system.
Описание: The first part of the book contains state-of-the-art overviews on the biological role of FcR. The latest information on FcR heterogeneity, FcR physiology, FcR-ligand recognition, their crucial coordinating role in immunity, interactions with other immunoreceptors, and the role of FcR in immunoglobulin transport and catabolism are discussed.
Автор: Michael R Shurin; Yuri S. Smolkin Название: Immune Mediated Diseases ISBN: 1441924604 ISBN-13(EAN): 9781441924605 Издательство: Springer Рейтинг: Цена: 36197.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume includes contributions from the speakers of the Second IMD Congress (September 10-15, 2007; The goal of the International Immune-Mediated Diseases: From Theory to Therapy (IMD) Congress is to bring the world`s best immunologists and clinicians to Moscow.
Автор: Swathi Arur Название: Signaling-Mediated Control of Cell Division ISBN: 3319448196 ISBN-13(EAN): 9783319448190 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1. Role of chromatin modifications in germline stem cell differentiationPooja Flora, Maitreyi Upadhyay, Alicia McCarthy, Prashanth Rangan Prashanth Rangan prangan@albany.edu 2. Regulation of the balance between proliferation and differentiation in germline stem cells.Ramya Singh and David HansenDavid Donald Hansen dhansen@ucalgary.ca 3. Control of germ line stem cell lineages by diet and physiologyKaitlyn Laws and Daniela Drummond-BarbosaDaniela Barbosa dbarbosa@jhu.edu 4. Signal-mediated regulation of meiotic prophase I during oogenesisKenneth Trimmer and Swathi ArurSwathi Arur sarur@mdanderson.org 5. Prophase I: preparing chromosomes for segregation in the developing oocyteRachel Harney, Benjamin Alleva, Sarit SmolikovSarit Smolikov saritsmol@gmail.com 6. Translational control of germ cell decisionsKumari Pushpa, Amaresh Chaturbedi, Ganga Anil Kumar and Kuppuswamy SubramaniamK Subramaniam subbu@iitm.ac.in 7. Prostagladin signaling from oocyte to spermHieu Dinh Hoang and Michael MillerMichael Miller mamiller@uab.edu 8. Cell fate maintenance and reprogramming during the oocyte-to-embryotransition'Christina Fassnacht and Rafal CioskRafal Ciosk rafal.ciosk@fmi.ch 9. Maternal to zygotic transitions across evolutionRueyling Lin rueyling.lin@utsouthwestern.edu 10 Cell cycle regulation in oocytesKubiak JZ and Borsuk EUniversity of Rennes, FranceJacek Kubiak. jacek.kubiak@univ-rennes1.fr 11 Oocyte activation and fertilization: crucial sperm and oocyte factorsMarc Yeste, Celine Jones, Siti N. Amdani, Kevin CowardUniversity of OxfordMarc Yeste. marc.yeste@obs-gyn.ox.ac.uk
