Activating and Inhibitory Immunoglobulin-like Receptors, M. D. Cooper; T. Takai; J.V. Ravetch
Автор: Lefranc/Lefranc Название: THE IMMUNOGLOBULIN FACTSBOOK ISBN: 012441351X ISBN-13(EAN): 9780124413511 Издательство: Elsevier Science Рейтинг: Цена: 13980.00 р. Наличие на складе: Поставка под заказ.
Описание: This is a reference for all functional and ORF immunoglobulin genes. It includes information on immunoglobulin structural and biological properties, chain synthesis, gene chromosomal localization, organization of the IGH, IGK and IGL loci, and the immunoglobulin heavy, kappa and lambda loci.
Автор: Rast Название: Immune Receptors ISBN: 1617791385 ISBN-13(EAN): 9781617791383 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Immunology has made significant progress in the past decade, driven forward by rapidly advancing technology and a renewed interest in the vast realm of innate immunity. The receptors that mediate these functions are at the front lines of both protective and regulative roles of the immune system. In Immune Receptors: Methods and Protocols, expert researchers present a variety of experimental approaches to the characterization of immune receptors and the cell biology that mediates their functions. These include imaging techniques that aim to understand receptor localization and trafficking, techniques to measure receptor-ligand interactions, strategies to identify novel ligands and methods to analyze downstream receptor signaling, as well as strategies for genomic and proteomic characterization of receptor repertoires. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immune Receptors: Methods and Protocols offers technical descriptions and protocols that will be useful both to investigators who are interested in carrying out these procedures and to those who seek a deeper understanding of the bench science that lies behind the immunology literature.
Автор: Vivier Eric, Colonna Marco Название: Immunobiology of Natural Killer Cell Receptors ISBN: 3540260838 ISBN-13(EAN): 9783540260837 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in direct innate immune reactions against viruses, bacteria, parasites and other triggers of pathology, such as malignant transformation, all of which cause stress in affected cells. Importantly, NK cells also link the innate and adaptive immune responses, contributing to the initiation of adaptive immune responses and executing adaptive responses using the CD16 FcgRIIIA immunoglobulin Fc receptor. Such responses are mediated through two major effector functions, the direct cytolysis of target cells and the production of cytokines and chemokines. The authors focus here on the nature of recognition events by NK cells and address how these events are integrated to trigger these distinct and graded effector functions.
Автор: Tammy Kielian Название: Toll-like Receptors: Roles in Infection and Neuropathology ISBN: 3642269117 ISBN-13(EAN): 9783642269110 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book highlights traditional roles for TLRs in infectious diseases of the CNS. It also discusses recently emerging roles for TLRs in non-infectious neurodegenerative diseases and the challenges faced in these models with identifying endogenous ligands.
Автор: Wolf H. Fridman Название: Cell-Mediated Effects of Immunoglobulins ISBN: 1461285011 ISBN-13(EAN): 9781461285014 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Shedding light on the relationship between violence and contemporary society, this volume explores the distinctive but little-known theories of violence in the work of Georges Bataille and Jean Baudrillard, applying these to a range of violent events - events often labelled `inexplicable` - in order to show how even the most extreme of acts can be seen as socially meaningful.
Автор: Santosh Nigam; Gert Kunkel; Stephen M. Prescott Название: Platelet-Activating Factor and Related Lipid Mediators 2 ISBN: 1489901817 ISBN-13(EAN): 9781489901811 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Fifth International Conference held in Berlin, Germany, September 12,-16, 1995
Описание: The first part of the book contains state-of-the-art overviews on the biological role of FcR. The latest information on FcR heterogeneity, FcR physiology, FcR-ligand recognition, their crucial coordinating role in immunity, interactions with other immunoreceptors, and the role of FcR in immunoglobulin transport and catabolism are discussed.
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