Environmental Epigenomics in Health and Disease, Randy L. Jirtle; Frederick L. Tyson

Автор: Andrew E. Teschendorff
Название: Computational and Statistical Epigenomics
ISBN: 9401799261 ISBN-13(EAN): 9789401799263
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This book introduces the reader to modern computational and statistical tools for translational epigenomics research. Over the last decade, epigenomics has emerged as a key area of molecular biology, epidemiology and genome medicine. Epigenomics not only offers us a deeper understanding of fundamental cellular biology, but also provides us with the basis for an improved understanding and management of complex diseases. From novel biomarkers for risk prediction, early detection, diagnosis and prognosis of common diseases, to novel therapeutic strategies, epigenomics is set to play a key role in the personalized medicine of the future. In this book we introduce the reader to some of the most important computational and statistical methods for analyzing epigenomic data, with a special focus on DNA methylation. Topics include normalization, correction for cellular heterogeneity, batch effects, clustering, supervised analysis and integrative methods for systems epigenomics. This book will be of interest to students and researchers in bioinformatics, biostatistics, biologists and clinicians alike. Dr. Andrew E. Teschendorff is Head of the Computational Systems Genomics Lab at the CAS-MPG Partner Institute for Computational Biology, Shanghai, China, as well as an Honorary Research Fellow at the UCL Cancer Institute, University College London, UK.

Автор: Donnelly
Название: Environmental Health in Central and Eastern Europe
ISBN: 9048172101 ISBN-13(EAN): 9789048172108
Издательство: Springer
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Цена: 23058.00 р.
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Описание: This book presents the latest research in quantifying complex mixtures in the environment and analyzing their potential impact on human health.

Автор: Appasani
Название: Epigenomics
ISBN: 1107697832 ISBN-13(EAN): 9781107697836
Издательство: Cambridge Academ
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Цена: 10138.00 р.
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Описание: Leading experts from academia and both the biotechnology and pharmaceutical industries introduce the emerging field of epigenomics, covering a wide range of topics and methods such as basic chromatin biology, imprinting at genome-wide level, and the role of epigenomics in disease biology and epidemiology.