New Concepts in Viral Heart Disease, H.P. Schulthei?

Автор: Merten
Название: Viral Vectors for Gene Therapy
ISBN: 161779094X ISBN-13(EAN): 9781617790942
Издательство: Springer
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Цена: 22359.00 р.
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Описание: The huge potential for gene therapy to cure a wide range of diseases has led to high expectations and a great increase in research efforts in this area, particularly in the study of delivery via viral vectors, widely considered to be more efficient than DNA transfection.  In Viral Vectors for Gene Therapy: Methods and Protocols, experts in the field present a collection of their knowledge and experience featuring methodologies that involve virus production, transferring protocols, and evaluating the efficacy of gene products. While thoroughly covering the most popular viral vector systems of adenovirus, retrovirus, and adeno-associated virus, this detailed volume also explores less common viral vector systems such as baculovirus, herpes virus, and measles virus, the growing interest in which is creating a considerable demand for large scale manufacturing and purification procedures.  Written in the highly successful Methods in Molecular Biology™ series format, many chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and vital tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Viral Vectors for Gene Therapy: Methods and Protocols provides basic principles accessible to scientists from a wide variety of backgrounds for the development of gene therapy viral products that are safe and effective.

Автор: Heinz-Peter Schultheiss; Joachim-Friedrich Kapp; G
Название: Chronic Viral and Inflammatory Cardiomyopathy
ISBN: 3642421431 ISBN-13(EAN): 9783642421433
Издательство: Springer
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Цена: 23058.00 р.
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Описание: Overview on Chronic Viral Cardiomyopathy/Chronic Myocarditis.-Unsolved Medical Issues and New Targets for Further Research in Viral Myocarditis and Dilated Cardiomyopathy.- Frontiers in Viral Diagnostics.- Is Virus Persistence a Determinant for Disease Progression?- Parvovirus B19 - The Causative Agent of Dilated Cardiomyopathy or an Harmless Passenger of the Human Myocard?- Parvovirus B19: A New Emerging Pathogenic Agent of Inflammatory Cardiomyopathy.- Role of Hepatitis C Virus in Cardiomyopathies.-Recent Insights into the Role of Host Innate and Acquired Immunity Responses.- The Significance of Autoimmunity in Myocarditis.- The Roles of Immunity and Autoimmunity in Chronic Heart Failure.- Clinical Implications of Anti-Cardiac Immunity in Dilated Cardiomyopathy.- Inflammation and Cardiac Remodeling During Viral Myocarditis.- Is There a Virus Specific Matrix Destruction in the Course of Disease in Dilated Cardiomyopathy?- New Non-Invasive Approaches for the Diagnosis of Cardiomyopathy: MRI.-New Therapeutics Targets in Chronic Viral Cardiomyopathy.-Anti-Viral Treatment in Patients with Virus-Induced Cardiomyopathy.- Immunosuppressive Treatment of Chronic Non-Viral Myocarditis.-Immunoabsorption in Dilated Cardiomyopathy

Автор: Wolfgang B. Fischer
Название: Viral Membrane Proteins: Structure, Function, and Drug Design
ISBN: 1441934537 ISBN-13(EAN): 9781441934536
Издательство: Springer
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Цена: 27950.00 р.
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Описание: The range of information covered includes signal proteins, ion channels, and fusion proteins.This book has a place in the libraries of researchers and scientists in a wide array of fields, including protein chemistry, molecular biophysics, pharmaceutical science and research, bioanotechnology, molecular biology, and biochemistry.

Автор: Carlos E. Catalano
Название: Viral Genome Packaging: Genetics, Structure, and Mechanism
ISBN: 1441934324 ISBN-13(EAN): 9781441934321
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Viral Genome Packaging focuses on the process of genome "packaging" within a pre-formed viral procapsid. The chapters of this book concentrate on the biochemistry, enzymology and structural aspects of the genome packaging machinery. The biochemical, biophysical and structural aspects of genome packaging are examined in detail.