Plant ABC Transporters, Markus Geisler

Автор: Anthony M. George
Название: ABC Transporters - 40 Years on
ISBN: 3319234757 ISBN-13(EAN): 9783319234755
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This book provides new structural, biochemical, and clinical information on ABC transporters. The authors explore and describe the state of the art of research, knowledge, and prospects for the future for this important family of proteins. The first ABC transporter was discovered in 1973 and was named P-glycoprotein. It elicits resistance to cytotoxic drugs, chiefly in human tumours, within which chemotherapy failure is observed in about 50% of cases. Together with its complex pharmacology, and even a suspected role in Alzheimer’s disease, this ABC transporter still eludes a clinical solution to its multidrug resistance property. ABC transporters are integral membrane active proteins and they belong to one of the largest protein families across all species. Their myriad roles encompass the import or export of a diverse range of allocrites, including ion, nutrients, peptides, polysaccharides, lipids, and xenobiotics. They are of major medical importance with many members elaborating multidrug resistance in bacteria, fungi, yeast, parasites, and humans. Other ABC transporters are involved in a number of inherited diseases, including cystic fibrosis, macular degeneration, gout, and several other metabolic disorders

Автор: Kirk L. Hamilton; Daniel C Devor
Название: Ion Channels and Transporters of Epithelia in Health and Disease
ISBN: 1493933647 ISBN-13(EAN): 9781493933648
Издательство: Springer
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Цена: 34937.00 р.
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Описание: This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters.

Автор: Markus Geisler; Kees Venema
Название: Transporters and Pumps in Plant Signaling
ISBN: 3642265480 ISBN-13(EAN): 9783642265488
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Plants must adapt to changing environmental conditions. This volume highlights the role of transporters and pumps in the regulation of movement, long-range transport and compartmentalization of water, solutes, nutrients and classical signaling molecules.

Автор: Gordon L. Amidon; Wolfgang Sad?e
Название: Membrane Transporters as Drug Targets
ISBN: 147578631X ISBN-13(EAN): 9781475786316
Издательство: Springer
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Цена: 25155.00 р.
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Описание: Because progress in the field of transporters has been extraordinary, this volume will focus on recent advances in our understanding of the structure, function, physiology, and molecular biology of membrane transporters. There will be an emphasis on transporters as molecular targets for drug delivery and disposition in the body.

Автор: Mobasheri
Название: Facilitative Glucose Transporters in Articular Chondrocytes
ISBN: 3540788980 ISBN-13(EAN): 9783540788980
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Articular cartilage is a highly specialized avascular connective tissue. This multidisciplinary article reviews the molecular and morphological aspects of GLUT expression and function in chondrocytes and their mesenchymal and embryonic stem cell precursors.

Автор: Susan Napier; Matilda Bingham
Название: Transporters as Targets for Drugs
ISBN: 3642099696 ISBN-13(EAN): 9783642099694
Издательство: Springer
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Цена: 34799.00 р.
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Описание: In each volume of Transporters as Targets for Drugs an overview chapter introduces the newcomer to the topic covered. The series covers hot topics of frontier research summarized by reputed scientists in the field.